The pathologist and the residual tumor (R) classification. Hermanek, P & Wittekind, C Pathology, Research and Practice, 190(2):115–123, February, 1994.
The pathologist and the residual tumor (R) classification [link]Paper  abstract   bibtex   
The R classification, adopted in 1987 by the UICC, denotes absence or presence of residual tumor after treatment. Residual tumor may be localized in the area of the primary tumor and/or as distant metastases. R0 corresponds to resection for cure or complete remission. R1 to microscopic residual tumor, R2 to macroscopic residual tumor. The R classification takes into account clinical and pathological findings. A reliable classification requires the pathological examination of resection margins. The R classification has considerable clinical significance, particularly being a strong predictor of prognosis. General and specific procedures for performing pathological R classification on resection specimens of different organs will be described. New methods in R classification comprise imprint cytology, cytolocial examination of ascites, examination of bone marrow biopsy. The importance of these methods will have to be established in the future.
@article{hermanek_pathologist_1994,
	title = {The pathologist and the residual tumor ({R}) classification},
	volume = {190},
	issn = {0344-0338},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/8058567},
	abstract = {The R classification, adopted in 1987 by the UICC, denotes absence or presence of residual tumor after treatment. Residual tumor may be localized in the area of the primary tumor and/or as distant metastases. R0 corresponds to resection for cure or complete remission. R1 to microscopic residual tumor, R2 to macroscopic residual tumor. The R classification takes into account clinical and pathological findings. A reliable classification requires the pathological examination of resection margins. The R classification has considerable clinical significance, particularly being a strong predictor of prognosis. General and specific procedures for performing pathological R classification on resection specimens of different organs will be described. New methods in R classification comprise imprint cytology, cytolocial examination of ascites, examination of bone marrow biopsy. The importance of these methods will have to be established in the future.},
	number = {2},
	urldate = {2009-10-23},
	journal = {Pathology, Research and Practice},
	author = {Hermanek, P and Wittekind, C},
	month = feb,
	year = {1994},
	pmid = {8058567},
	keywords = {Humans, Neoplasms, Pathology, Postoperative Period},
	pages = {115--123},
}

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