Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease. Hernán, M. A., Logroscino, G., & García Rodríguez, L. A. Neurology, 66(7):1097--1099, April, 2006. doi abstract bibtex Animal and epidemiologic studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of Parkinson disease (PD). The authors studied 1,258 PD cases and 6,638 controls from the General Practice Research Database. The odds ratios (95% CI) for ever vs never use were 0.93 (0.80 to 1.08) for nonaspirin NSAIDs, 1.29 (1.05 to 1.58) for aspirin, and 1.16 (1.00 to 1.35) for acetaminophen. Nonaspirin NSAID use was associated with a higher risk in women and a lower risk in men.
@article{hernan_nonsteroidal_2006,
title = {Nonsteroidal anti-inflammatory drugs and the incidence of {Parkinson} disease},
volume = {66},
issn = {1526-632X},
doi = {10.1212/01.wnl.0000204446.82823.28},
abstract = {Animal and epidemiologic studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of Parkinson disease (PD). The authors studied 1,258 PD cases and 6,638 controls from the General Practice Research Database. The odds ratios (95\% CI) for ever vs never use were 0.93 (0.80 to 1.08) for nonaspirin NSAIDs, 1.29 (1.05 to 1.58) for aspirin, and 1.16 (1.00 to 1.35) for acetaminophen. Nonaspirin NSAID use was associated with a higher risk in women and a lower risk in men.},
language = {eng},
number = {7},
journal = {Neurology},
author = {Hernán, Miguel A. and Logroscino, Giancarlo and García Rodríguez, Luis A.},
month = apr,
year = {2006},
pmid = {16606925},
keywords = {Acetaminophen, Aged, Anti-Inflammatory Agents, Non-Steroidal, Antiparkinson Agents, Aspirin, Case-Control Studies, Cohort Studies, Databases, Factual, Family Practice, Female, Great Britain, Humans, Male, Parkinson Disease, Sex Characteristics, Tremor, incidence},
pages = {1097--1099}
}
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