Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs. Hernández-Díaz, S. & García-Rodríguez, L. A. The American Journal of Medicine, 110 Suppl 3A:20S--7S, February, 2001.
abstract   bibtex   
The use of conventional nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with upper gastrointestinal bleeding and perforation (UGIB), acute liver injury, acute renal injury, heart failure, and adverse reproductive outcomes. This article summarizes the effects of various factors, such as NSAID dose, duration of treatment, patient age, and ulcer history, on the incidences of these adverse side effects. We used the UK General Practice Research Database to study further the principal safety concern related to NSAIDs, namely, UGIB.
@article{hernandez-diaz_epidemiologic_2001,
	title = {Epidemiologic assessment of the safety of conventional nonsteroidal anti-inflammatory drugs},
	volume = {110 Suppl 3A},
	issn = {0002-9343},
	abstract = {The use of conventional nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with upper gastrointestinal bleeding and perforation (UGIB), acute liver injury, acute renal injury, heart failure, and adverse reproductive outcomes. This article summarizes the effects of various factors, such as NSAID dose, duration of treatment, patient age, and ulcer history, on the incidences of these adverse side effects. We used the UK General Practice Research Database to study further the principal safety concern related to NSAIDs, namely, UGIB.},
	language = {eng},
	journal = {The American Journal of Medicine},
	author = {Hernández-Díaz, S. and García-Rodríguez, L. A.},
	month = feb,
	year = {2001},
	pmid = {11173046},
	keywords = {Acute Disease, Adult, Aged, Anti-Inflammatory Agents, Non-Steroidal, Databases, Factual, Drug-Induced Liver Injury, Family Practice, Female, Gastrointestinal Hemorrhage, Great Britain, Heart Failure, Humans, Kidney Diseases, Liver Diseases, Male, Middle Aged, Reproduction, Risk Factors, Safety, incidence, pharmacoepidemiology, pregnancy},
	pages = {20S--7S}
}
Downloads: 0