MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction.

MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction. Hirsch, S., Guo, J., Reiter, R., Papazoglou, S., Kroencke, T., Braun, J., & Sack, I. Magn Reson Med, Feb, 2013.

Paper doi abstract bibtex

PURPOSE: Viscoelastic properties of the liver are sensitive to fibrosis. This study proposes several modifications to existing magnetic resonance elastography (MRE) techniques to improve the accuracy of abdominal MRE. METHODS: The proposed method comprises the following steps: (i) wave generation by a nonmagnetic, piezoelectric driver suitable for integration into the patient table, (ii) fast single-shot 3D wave-field acquisition at four drive frequencies between 30 and 60 Hz, and (iii) single-step postprocessing by a novel multifrequency dual parameter inversion of the wave equation. The method is tested in phantoms, healthy volunteers, and patients with portal hypertension and ascites. RESULTS: Spatial maps of magnitude and phase of the complex shear modulus were acquired within 6-8 min. These maps are not subject to bias from inversion-related artifacts known from classic MRE. The spatially averaged modulus for healthy liver was 1.44?�?0.23 kPa with ??=?0.492?�?0.064. Both parameters were significantly higher in the spleen (2.29?�?0.97 kPa, P?=?0.015 and 0.749?�?0.144, P?=?6.58�10(-5) , respectively). CONCLUSION: The proposed method provides abdominal images of viscoelasticity in a short time with spatial resolution comparable to conventional MR images and improved quality without being compromised by ascites. The new setup allows for the integration of abdominal MRE into the clinical workflow. Magn Reson Med, 2013. � 2013 Wiley Periodicals, Inc.

@article{ Hirsch2013b,
  author = {Hirsch, Sebastian and Guo, Jing and Reiter, Rolf and Papazoglou,
	Sebastian and Kroencke, Thomas and Braun, Juergen and Sack, Ingolf},
  title = {MR Elastography of the Liver and the Spleen Using a Piezoelectric
	Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual
	Parameter Reconstruction.},
  journal = {Magn Reson Med},
  year = {2013},
  month = {Feb},
  abstract = {PURPOSE: Viscoelastic properties of the liver are sensitive to fibrosis.
	This study proposes several modifications to existing magnetic resonance
	elastography (MRE) techniques to improve the accuracy of abdominal
	MRE. METHODS: The proposed method comprises the following steps:
	(i) wave generation by a nonmagnetic, piezoelectric driver suitable
	for integration into the patient table, (ii) fast single-shot 3D
	wave-field acquisition at four drive frequencies between 30 and 60
	Hz, and (iii) single-step postprocessing by a novel multifrequency
	dual parameter inversion of the wave equation. The method is tested
	in phantoms, healthy volunteers, and patients with portal hypertension
	and ascites. RESULTS: Spatial maps of magnitude and phase of the
	complex shear modulus were acquired within 6-8 min. These maps are
	not subject to bias from inversion-related artifacts known from classic
	MRE. The spatially averaged modulus for healthy liver was 1.44?�?0.23
	kPa with ??=?0.492?�?0.064. Both parameters were significantly higher
	in the spleen (2.29?�?0.97 kPa, P?=?0.015 and 0.749?�?0.144, P?=?6.58�10(-5)
	, respectively). CONCLUSION: The proposed method provides abdominal
	images of viscoelasticity in a short time with spatial resolution
	comparable to conventional MR images and improved quality without
	being compromised by ascites. The new setup allows for the integration
	of abdominal MRE into the clinical workflow. Magn Reson Med, 2013.
	� 2013 Wiley Periodicals, Inc.},
  doi = {10.1002/mrm.24674},
  institution = {Department of Radiology, Charit�-Universit�tsmedizin Berlin, Campus
	Charit� Mitte, Berlin, Germany.},
  language = {eng},
  medline-pst = {aheadofprint},
  owner = {Heiko},
  pmid = {23413115},
  timestamp = {2013.07.26},
  url = {http://dx.doi.org/10.1002/mrm.24674}
}

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[.24674]\" \n\t class=\"bibbase_icon\"\n\t style=\"width: 24px; height: 24px; border: 0px; vertical-align: text-top\" ><span class=\"bibbase_icon_text\">Paper</span></a> \n \n \n <a href=\"javascript:showBib('Hirsch2013b')\">\n <img src=\"http://www.bibbase.org/img/filetypes/bib.png\" \n\t alt=\"MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction. [bib]\" \n\t class=\"bibbase_icon\"\n\t style=\"width: 24px; height: 24px; border: 0px; vertical-align: text-top\"><span class=\"bibbase_icon_text\">Bibtex</span></a>\n \n   \n\n \n \n  \n \n \n\n \n <a class=\"bibbase_abstract_link\" href=\"javascript:showAbstract('Hirsch2013b')\">Abstract</a>\n \n \n</span>\n\n\n\n\n\n\n\n</div>\n","downloads":0,"abstract":"PURPOSE: Viscoelastic properties of the liver are sensitive to fibrosis. This study proposes several modifications to existing magnetic resonance elastography (MRE) techniques to improve the accuracy of abdominal MRE. METHODS: The proposed method comprises the following steps: (i) wave generation by a nonmagnetic, piezoelectric driver suitable for integration into the patient table, (ii) fast single-shot 3D wave-field acquisition at four drive frequencies between 30 and 60 Hz, and (iii) single-step postprocessing by a novel multifrequency dual parameter inversion of the wave equation. The method is tested in phantoms, healthy volunteers, and patients with portal hypertension and ascites. RESULTS: Spatial maps of magnitude and phase of the complex shear modulus were acquired within 6-8 min. These maps are not subject to bias from inversion-related artifacts known from classic MRE. The spatially averaged modulus for healthy liver was 1.44?�?0.23 kPa with ??=?0.492?�?0.064. Both parameters were significantly higher in the spleen (2.29?�?0.97 kPa, P?=?0.015 and 0.749?�?0.144, P?=?6.58�10(-5) , respectively). CONCLUSION: The proposed method provides abdominal images of viscoelasticity in a short time with spatial resolution comparable to conventional MR images and improved quality without being compromised by ascites. The new setup allows for the integration of abdominal MRE into the clinical workflow. Magn Reson Med, 2013. � 2013 Wiley Periodicals, Inc.","author":["Hirsch, Sebastian","Guo, Jing","Reiter, Rolf","Papazoglou, Sebastian","Kroencke, Thomas","Braun, Juergen","Sack, Ingolf"],"author_short":["Hirsch, S.","Guo, J.","Reiter, R.","Papazoglou, S.","Kroencke, T.","Braun, J.","Sack, I."],"bibtex":"@article{ Hirsch2013b,\n author = {Hirsch, Sebastian and Guo, Jing and Reiter, Rolf and Papazoglou,\r\n\tSebastian and Kroencke, Thomas and Braun, Juergen and Sack, Ingolf},\n title = {MR Elastography of the Liver and the Spleen Using a Piezoelectric\r\n\tDriver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual\r\n\tParameter Reconstruction.},\n journal = {Magn Reson Med},\n year = {2013},\n month = {Feb},\n abstract = {PURPOSE: Viscoelastic properties of the liver are sensitive to fibrosis.\r\n\tThis study proposes several modifications to existing magnetic resonance\r\n\telastography (MRE) techniques to improve the accuracy of abdominal\r\n\tMRE. METHODS: The proposed method comprises the following steps:\r\n\t(i) wave generation by a nonmagnetic, piezoelectric driver suitable\r\n\tfor integration into the patient table, (ii) fast single-shot 3D\r\n\twave-field acquisition at four drive frequencies between 30 and 60\r\n\tHz, and (iii) single-step postprocessing by a novel multifrequency\r\n\tdual parameter inversion of the wave equation. The method is tested\r\n\tin phantoms, healthy volunteers, and patients with portal hypertension\r\n\tand ascites. RESULTS: Spatial maps of magnitude and phase of the\r\n\tcomplex shear modulus were acquired within 6-8 min. These maps are\r\n\tnot subject to bias from inversion-related artifacts known from classic\r\n\tMRE. The spatially averaged modulus for healthy liver was 1.44?�?0.23\r\n\tkPa with ??=?0.492?�?0.064. Both parameters were significantly higher\r\n\tin the spleen (2.29?�?0.97 kPa, P?=?0.015 and 0.749?�?0.144, P?=?6.58�10(-5)\r\n\t, respectively). CONCLUSION: The proposed method provides abdominal\r\n\timages of viscoelasticity in a short time with spatial resolution\r\n\tcomparable to conventional MR images and improved quality without\r\n\tbeing compromised by ascites. The new setup allows for the integration\r\n\tof abdominal MRE into the clinical workflow. Magn Reson Med, 2013.\r\n\t� 2013 Wiley Periodicals, Inc.},\n doi = {10.1002/mrm.24674},\n institution = {Department of Radiology, Charit�-Universit�tsmedizin Berlin, Campus\r\n\tCharit� Mitte, Berlin, Germany.},\n language = {eng},\n medline-pst = {aheadofprint},\n owner = {Heiko},\n pmid = {23413115},\n timestamp = {2013.07.26},\n url = {http://dx.doi.org/10.1002/mrm.24674}\n}","bibtype":"article","doi":"10.1002/mrm.24674","id":"Hirsch2013b","institution":"Department of Radiology, Charit�-Universit�tsmedizin Berlin, Campus Charit� Mitte, Berlin, Germany.","journal":"Magn Reson Med","key":"Hirsch2013b","language":"eng","medline-pst":"aheadofprint","month":"Feb","owner":"Heiko","pmid":"23413115","timestamp":"2013.07.26","title":"MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction.","type":"article","url":"http://dx.doi.org/10.1002/mrm.24674","year":"2013","role":"author","urls":{"Paper":"http://dx.doi.org/10.1002/mrm.24674"},"bibbaseid":"hirsch-guo-reiter-papazoglou-kroencke-braun-sack-mrelastographyoftheliverandthespleenusingapiezoelectricdriversingleshotwavefieldacquisitionandmultifrequencydualparameterreconstruction-2013"},"bibtype":"article","biburl":"http://home.arcor.de/teambushido/Literatur.bib","downloads":0,"title":"MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction.","year":2013,"dataSources":["z828pEjP7GR5ew7B7"]}