@article{hirvonen_aberrant_2022,
	title = {Aberrant long-range temporal correlations in oscillation dynamics characterize adult {Attention} {Deficit} and {Hyperactivity} {Disorder}},
	volume = {in press},
	abstract = {Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by involuntary fluctuations of attention specifically in continuous performance tasks (CPTs), in which attention must be sustained over long period of time. The neuronal basis of aberrant attentional fluctuations in ADHD are poorly understood. Healthy brain activity is characterized by neuronal oscillations that are fundamental for cognition and behavior. Long-range temporal correlations (LRTCs) in the strength of oscillations predict fluctuations and dynamics in behavioral performance in CPTs. 
Methods: We investigated here whether aberrant behavioral fluctuations characteristic to ADHD could originate from aberrant neuronal LRTCs. Brain activity was measured with magnetoencephalography (MEG) from 23 adult participants diagnosed with ADHD, and from 23 healthy controls during rest and during CPTs. 
Results: Adult ADHD was associated with atypical task-dependent modulations of LRTCs of oscillation amplitude fluctuations compared to healthy controls. The aberrant LRCTs originated from frontal and parietal, and sensory cortical areas associated with attentional control. The LRTCs were further correlated with the variability in behavioral LRTCs in CPTs and with the severity of ADHD symptoms. 
Conclusions: These data demonstrate that altered LRTCs in oscillation amplitudes constitute to the aberrant involuntary fluctuations of attention of adults with ADHD.},
	journal = {Biological Psychiatry},
	author = {Hirvonen, Jonni and Simola, Jaana and Morales-Muñoz, Isabel and Cowley, Benjamin Ultan and Palva, J Matias and Palva, Satu},
	year = {2022},
}

{"_id":"jv4tgtJsPFHF3YSj9","bibbaseid":"hirvonen-simola-moralesmuoz-cowley-palva-palva-aberrantlongrangetemporalcorrelationsinoscillationdynamicscharacterizeadultattentiondeficitandhyperactivitydisorder-2022","author_short":["Hirvonen, J.","Simola, J.","Morales-Muñoz, I.","Cowley, B. U.","Palva, J M.","Palva, S."],"bibdata":{"bibtype":"article","type":"article","title":"Aberrant long-range temporal correlations in oscillation dynamics characterize adult Attention Deficit and Hyperactivity Disorder","volume":"in press","abstract":"Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by involuntary fluctuations of attention specifically in continuous performance tasks (CPTs), in which attention must be sustained over long period of time. The neuronal basis of aberrant attentional fluctuations in ADHD are poorly understood. Healthy brain activity is characterized by neuronal oscillations that are fundamental for cognition and behavior. Long-range temporal correlations (LRTCs) in the strength of oscillations predict fluctuations and dynamics in behavioral performance in CPTs. Methods: We investigated here whether aberrant behavioral fluctuations characteristic to ADHD could originate from aberrant neuronal LRTCs. Brain activity was measured with magnetoencephalography (MEG) from 23 adult participants diagnosed with ADHD, and from 23 healthy controls during rest and during CPTs. Results: Adult ADHD was associated with atypical task-dependent modulations of LRTCs of oscillation amplitude fluctuations compared to healthy controls. The aberrant LRCTs originated from frontal and parietal, and sensory cortical areas associated with attentional control. The LRTCs were further correlated with the variability in behavioral LRTCs in CPTs and with the severity of ADHD symptoms. Conclusions: These data demonstrate that altered LRTCs in oscillation amplitudes constitute to the aberrant involuntary fluctuations of attention of adults with ADHD.","journal":"Biological Psychiatry","author":[{"propositions":[],"lastnames":["Hirvonen"],"firstnames":["Jonni"],"suffixes":[]},{"propositions":[],"lastnames":["Simola"],"firstnames":["Jaana"],"suffixes":[]},{"propositions":[],"lastnames":["Morales-Muñoz"],"firstnames":["Isabel"],"suffixes":[]},{"propositions":[],"lastnames":["Cowley"],"firstnames":["Benjamin","Ultan"],"suffixes":[]},{"propositions":[],"lastnames":["Palva"],"firstnames":["J","Matias"],"suffixes":[]},{"propositions":[],"lastnames":["Palva"],"firstnames":["Satu"],"suffixes":[]}],"year":"2022","bibtex":"@article{hirvonen_aberrant_2022,\n\ttitle = {Aberrant long-range temporal correlations in oscillation dynamics characterize adult {Attention} {Deficit} and {Hyperactivity} {Disorder}},\n\tvolume = {in press},\n\tabstract = {Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by involuntary fluctuations of attention specifically in continuous performance tasks (CPTs), in which attention must be sustained over long period of time. The neuronal basis of aberrant attentional fluctuations in ADHD are poorly understood. Healthy brain activity is characterized by neuronal oscillations that are fundamental for cognition and behavior. Long-range temporal correlations (LRTCs) in the strength of oscillations predict fluctuations and dynamics in behavioral performance in CPTs. \nMethods: We investigated here whether aberrant behavioral fluctuations characteristic to ADHD could originate from aberrant neuronal LRTCs. Brain activity was measured with magnetoencephalography (MEG) from 23 adult participants diagnosed with ADHD, and from 23 healthy controls during rest and during CPTs. \nResults: Adult ADHD was associated with atypical task-dependent modulations of LRTCs of oscillation amplitude fluctuations compared to healthy controls. The aberrant LRCTs originated from frontal and parietal, and sensory cortical areas associated with attentional control. The LRTCs were further correlated with the variability in behavioral LRTCs in CPTs and with the severity of ADHD symptoms. \nConclusions: These data demonstrate that altered LRTCs in oscillation amplitudes constitute to the aberrant involuntary fluctuations of attention of adults with ADHD.},\n\tjournal = {Biological Psychiatry},\n\tauthor = {Hirvonen, Jonni and Simola, Jaana and Morales-Muñoz, Isabel and Cowley, Benjamin Ultan and Palva, J Matias and Palva, Satu},\n\tyear = {2022},\n}\n\n","author_short":["Hirvonen, J.","Simola, J.","Morales-Muñoz, I.","Cowley, B. U.","Palva, J M.","Palva, S."],"key":"hirvonen_aberrant_2022","id":"hirvonen_aberrant_2022","bibbaseid":"hirvonen-simola-moralesmuoz-cowley-palva-palva-aberrantlongrangetemporalcorrelationsinoscillationdynamicscharacterizeadultattentiondeficitandhyperactivitydisorder-2022","role":"author","urls":{},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://api.zotero.org/users/19634/collections/TV78LMMA/items?key=zgrPlGGTKEmHxe9fkceMr5cH&format=bibtex&limit=100","dataSources":["AQiMfQvX7ga5gRq8M"],"keywords":[],"search_terms":["aberrant","long","range","temporal","correlations","oscillation","dynamics","characterize","adult","attention","deficit","hyperactivity","disorder","hirvonen","simola","morales-muñoz","cowley","palva","palva"],"title":"Aberrant long-range temporal correlations in oscillation dynamics characterize adult Attention Deficit and Hyperactivity Disorder","year":2022}