Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial. Ho, H. J., Tan, Y., Cook, A. R., Koh, G., Tham, T. Y., Anwar, E., Hui Chiang, G. S., Lwin, M. O., & Chen, M. I. American Journal of Public Health, 109(12):1776–1783, 2019.
Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial [link]Paper  doi  abstract   bibtex   
Objectives. To evaluate the effectiveness of point-of-care informational interventions in general practitioner clinics to improve influenza and pneumococcal vaccination uptake among elderly patients. Methods. We conducted a pragmatic, cluster-randomized crossover trial in 22 private general practitioner clinics in Singapore, from November 2017 to July 2018. We included all patients aged 65 years or older. Clinics were assigned to a 3-month intervention (flyers and posters encouraging vaccination) plus 1-month washout period, and a 4-month control period (usual care). Primary outcomes were differences in vaccination uptake rates between periods. Secondary outcomes were identification of other factors associated with vaccination uptake. Results. A total of 4378 and 4459 patients were included in the intervention and control periods, respectively. Both influenza (5.9% vs 4.8%; P =.047) and pneumococcal (5.7% vs 3.7%; P =.001) vaccination uptake rates were higher during the intervention period compared with the control period. On multilevel logistic regression analysis, follow-up for hypertension, diabetes mellitus, hyperlipidemia, or any combination of the 3 was associated with uptake of both vaccines. Conclusions. Point-of-care informational interventions likely contributed to increased influenza and pneumococcal vaccination uptake. Patients on follow-up for hypertension, diabetes mellitus, hyperlipidemia, or any combination of the 3 were more likely to receive influenza and pneumococcal vaccination and should be actively engaged by physicians. Trial Registration. ClinicalTrials.gov Identifier: NCT03445117.
@article{ho_increasing_2019,
	title = {Increasing {Influenza} and {Pneumococcal} {Vaccination} {Uptake} in {Seniors} {Using} {Point}-of-{Care} {Informational} {Interventions} in {Primary} {Care} in {Singapore}: {A} {Pragmatic}, {Cluster}-{Randomized} {Crossover} {Trial}},
	volume = {109},
	issn = {0090-0036},
	url = {http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=139529086&site=ehost-live},
	doi = {10.2105/AJPH.2019.305328},
	abstract = {Objectives. To evaluate the effectiveness of point-of-care informational interventions in general practitioner clinics to improve influenza and pneumococcal vaccination uptake among elderly patients. Methods. We conducted a pragmatic, cluster-randomized crossover trial in 22 private general practitioner clinics in Singapore, from November 2017 to July 2018. We included all patients aged 65 years or older. Clinics were assigned to a 3-month intervention (flyers and posters encouraging vaccination) plus 1-month washout period, and a 4-month control period (usual care). Primary outcomes were differences in vaccination uptake rates between periods. Secondary outcomes were identification of other factors associated with vaccination uptake. Results. A total of 4378 and 4459 patients were included in the intervention and control periods, respectively. Both influenza (5.9\% vs 4.8\%; P =.047) and pneumococcal (5.7\% vs 3.7\%; P =.001) vaccination uptake rates were higher during the intervention period compared with the control period. On multilevel logistic regression analysis, follow-up for hypertension, diabetes mellitus, hyperlipidemia, or any combination of the 3 was associated with uptake of both vaccines. Conclusions. Point-of-care informational interventions likely contributed to increased influenza and pneumococcal vaccination uptake. Patients on follow-up for hypertension, diabetes mellitus, hyperlipidemia, or any combination of the 3 were more likely to receive influenza and pneumococcal vaccination and should be actively engaged by physicians. Trial Registration. ClinicalTrials.gov Identifier: NCT03445117.},
	number = {12},
	journal = {American Journal of Public Health},
	author = {Ho, Hanley J. and Tan, Yi-Roe and Cook, Alex R. and Koh, Gerald and Tham, Tat Yean and Anwar, Eve and Hui Chiang, Grace Shu and Lwin, May O. and Chen, Mark I.},
	year = {2019},
	keywords = {After Care, Aged, Attitude to Vaccines -- Evaluation, Comorbidity -- Evaluation, Funding Source, Human, Influenza Vaccine -- In Old Age, Logistic Regression, Outcome Assessment, Patient Education, Physicians, Family, Pneumococcal Vaccine -- In Old Age, Point-of-Care Testing, Primary Health Care -- Singapore, Professional Role, Randomized Controlled Trials, Singapore, Vaccination Coverage -- Statistics and Numerical Data},
	pages = {1776--1783},
}

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