Helminths are positively AMPing up gut de-bugging. Horsnell, W. G C & Oudhoff, M. J Cell Host & Microbe, 30(1):1–2, Elsevier, jan, 2022.
Paper doi abstract bibtex In recently published work, Hu, Zhang, and colleagues identify SPRR2A as a novel intestinal antimicrobial protein (AMP) that targets Gram-positive bacteria (Hu et al., 2021). Unexpectedly, the authors show that SPRR2A is induced by helminth-elicited type 2 immunity to restrict pathogenic bacteria translocation across the helminth-infection-damaged epithelium.
@article{Horsnell2022,
abstract = {In recently published work, Hu, Zhang, and colleagues identify SPRR2A as a novel intestinal antimicrobial protein (AMP) that targets Gram-positive bacteria (Hu et al., 2021). Unexpectedly, the authors show that SPRR2A is induced by helminth-elicited type 2 immunity to restrict pathogenic bacteria translocation across the helminth-infection-damaged epithelium.},
author = {Horsnell, William G C and Oudhoff, Menno J},
doi = {10.1016/J.CHOM.2021.12.016},
issn = {1931-3128},
journal = {Cell Host {\&} Microbe},
keywords = {original},
mendeley-tags = {original},
month = {jan},
number = {1},
pages = {1--2},
pmid = {35026130},
publisher = {Elsevier},
title = {{Helminths are positively AMPing up gut de-bugging}},
url = {http://www.cell.com/article/S1931312821005874/fulltext http://www.cell.com/article/S1931312821005874/abstract https://www.cell.com/cell-host-microbe/abstract/S1931-3128(21)00587-4},
volume = {30},
year = {2022}
}
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