Super-Resolution Fluorescence Microscopy

Super-Resolution Fluorescence Microscopy. Huang, B., Bates, M., & Zhuang, X. Annual Review of Biochemistry, 78(1):993--1016, 2009.

Paper doi abstract bibtex

Achieving a spatial resolution that is not limited by the diffraction of light, recent developments of super-resolution fluorescence microscopy techniques allow the observation of many biological structures not resolvable in conventional fluorescence microscopy. New advances in these techniques now give them the ability to image three-dimensional (3D) structures, measure interactions by multicolor colocalization, and record dynamic processes in living cells at the nanometer scale. It is anticipated that super-resolution fluorescence microscopy will become a widely used tool for cell and tissue imaging to provide previously unobserved details of biological structures and processes.

@article{huang_super-resolution_2009,
	title = {Super-{Resolution} {Fluorescence} {Microscopy}},
	volume = {78},
	url = {http://dx.doi.org/10.1146/annurev.biochem.77.061906.092014},
	doi = {10.1146/annurev.biochem.77.061906.092014},
	abstract = {Achieving a spatial resolution that is not limited by the diffraction of light, recent developments of super-resolution fluorescence microscopy techniques allow the observation of many biological structures not resolvable in conventional fluorescence microscopy. New advances in these techniques now give them the ability to image three-dimensional (3D) structures, measure interactions by multicolor colocalization, and record dynamic processes in living cells at the nanometer scale. It is anticipated that super-resolution fluorescence microscopy will become a widely used tool for cell and tissue imaging to provide previously unobserved details of biological structures and processes.},
	number = {1},
	urldate = {2016-03-17TZ},
	journal = {Annual Review of Biochemistry},
	author = {Huang, Bo and Bates, Mark and Zhuang, Xiaowei},
	year = {2009},
	pmid = {19489737},
	keywords = {Fluorescence imaging, diffraction limit, fluorescent protein, live-cell imaging, photoswitchable dye, single molecule},
	pages = {993--1016}
}

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