The Long-Term Prognostic Significance of 6-Minute Walk Test Distance in Patients with Chronic Heart Failure. Ingle, L., Cleland, J. G., & Clark, A. L. BioMed Research International, 2014:1–7, 2014.
Paper doi abstract bibtex Background . The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup (\textgreater5 years) is unclear. Methods . 1,667 patients (median [inter-quartile range, IQR]) (age 72 [65–77]; 75% males) with heart failure due to left ventricular systolic impairment undertook a 6-MWT as part of their baseline assessment and were followed up for 5 years. Results . At 5 years’ followup, those patients who died ( n = 959) were older at baseline and had a higher log NT pro-BNP than those who survived to 5 years ( n = 708). 6-MWT distance was lower in those who died [163 (153) m versus 269 (160) m; P \textless 0.0001]. Median 6-MWT distance was 300 (150–376) m, and quartile ranges were \textless46 m, 46–240 m, 241–360 m, and \textgreater360 m. 6-MWT distance was a predictor of all-cause mortality (HR 0.97; 95% CI 0.96-0.97; Chi-square = 184.1; P \textless 0.0001). Independent predictors of all-cause mortality were decreasing 6-MWT distance, increasing age, increasing NYHA classification, increasing log NT pro-BNP, decreasing diastolic blood pressure, decreasing sodium, and increasing urea. Conclusion . The 6-MWT is an important independent predictor of all-cause mortality following long-term followup in patients with CHF.
@article{ingle_long-term_2014-1,
title = {The {Long}-{Term} {Prognostic} {Significance} of 6-{Minute} {Walk} {Test} {Distance} in {Patients} with {Chronic} {Heart} {Failure}},
volume = {2014},
issn = {2314-6133, 2314-6141},
url = {http://www.hindawi.com/journals/bmri/2014/505969/},
doi = {10.1155/2014/505969},
abstract = {Background . The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup ({\textbackslash}textgreater5 years) is unclear. Methods . 1,667 patients (median [inter-quartile range, IQR]) (age 72 [65–77]; 75\% males) with heart failure due to left ventricular systolic impairment undertook a 6-MWT as part of their baseline assessment and were followed up for 5 years. Results . At 5 years’ followup, those patients who died ( n = 959) were older at baseline and had a higher log NT pro-BNP than those who survived to 5 years ( n = 708). 6-MWT distance was lower in those who died [163 (153) m versus 269 (160) m; P {\textbackslash}textless 0.0001]. Median 6-MWT distance was 300 (150–376) m, and quartile ranges were {\textbackslash}textless46 m, 46–240 m, 241–360 m, and {\textbackslash}textgreater360 m. 6-MWT distance was a predictor of all-cause mortality (HR 0.97; 95\% CI 0.96-0.97; Chi-square = 184.1; P {\textbackslash}textless 0.0001). Independent predictors of all-cause mortality were decreasing 6-MWT distance, increasing age, increasing NYHA classification, increasing log NT pro-BNP, decreasing diastolic blood pressure, decreasing sodium, and increasing urea. Conclusion . The 6-MWT is an important independent predictor of all-cause mortality following long-term followup in patients with CHF.},
language = {en},
urldate = {2021-04-28},
journal = {BioMed Research International},
author = {Ingle, Lee and Cleland, John G. and Clark, Andrew L.},
year = {2014},
pages = {1--7},
file = {Ingle et al. - 2014 - The Long-Term Prognostic Significance of 6-Minute .pdf:/Users/neil.hawkins/Zotero/storage/UPUKG258/Ingle et al. - 2014 - The Long-Term Prognostic Significance of 6-Minute .pdf:application/pdf},
}
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At 5 years’ followup, those patients who died ( n = 959) were older at baseline and had a higher log NT pro-BNP than those who survived to 5 years ( n = 708). 6-MWT distance was lower in those who died [163 (153) m versus 269 (160) m; P \\textless 0.0001]. Median 6-MWT distance was 300 (150–376) m, and quartile ranges were \\textless46 m, 46–240 m, 241–360 m, and \\textgreater360 m. 6-MWT distance was a predictor of all-cause mortality (HR 0.97; 95% CI 0.96-0.97; Chi-square = 184.1; P \\textless 0.0001). Independent predictors of all-cause mortality were decreasing 6-MWT distance, increasing age, increasing NYHA classification, increasing log NT pro-BNP, decreasing diastolic blood pressure, decreasing sodium, and increasing urea. Conclusion . The 6-MWT is an important independent predictor of all-cause mortality following long-term followup in patients with CHF.","language":"en","urldate":"2021-04-28","journal":"BioMed Research International","author":[{"propositions":[],"lastnames":["Ingle"],"firstnames":["Lee"],"suffixes":[]},{"propositions":[],"lastnames":["Cleland"],"firstnames":["John","G."],"suffixes":[]},{"propositions":[],"lastnames":["Clark"],"firstnames":["Andrew","L."],"suffixes":[]}],"year":"2014","pages":"1–7","file":"Ingle et al. - 2014 - The Long-Term Prognostic Significance of 6-Minute .pdf:/Users/neil.hawkins/Zotero/storage/UPUKG258/Ingle et al. - 2014 - The Long-Term Prognostic Significance of 6-Minute .pdf:application/pdf","bibtex":"@article{ingle_long-term_2014-1,\n\ttitle = {The {Long}-{Term} {Prognostic} {Significance} of 6-{Minute} {Walk} {Test} {Distance} in {Patients} with {Chronic} {Heart} {Failure}},\n\tvolume = {2014},\n\tissn = {2314-6133, 2314-6141},\n\turl = {http://www.hindawi.com/journals/bmri/2014/505969/},\n\tdoi = {10.1155/2014/505969},\n\tabstract = {Background . The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup ({\\textbackslash}textgreater5 years) is unclear. Methods . 1,667 patients (median [inter-quartile range, IQR]) (age 72 [65–77]; 75\\% males) with heart failure due to left ventricular systolic impairment undertook a 6-MWT as part of their baseline assessment and were followed up for 5 years. Results . At 5 years’ followup, those patients who died ( n = 959) were older at baseline and had a higher log NT pro-BNP than those who survived to 5 years ( n = 708). 6-MWT distance was lower in those who died [163 (153) m versus 269 (160) m; P {\\textbackslash}textless 0.0001]. 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