Comparative analysis of the nucleosome structure of cell nuclei by small-angle neutron scattering. Isaev-Ivanov, V., Lebedev, D., Lauter, H., Pantina, R., Kuklin, A., Islamov, A., & Filatov, M. Physics of the Solid State, 52(5):1063-1073, 2010. cited By 4
Comparative analysis of the nucleosome structure of cell nuclei by small-angle neutron scattering [link]Paper  doi  abstract   bibtex   
The nucleosome structure in native nuclei of normal (chicken erythrocyte and rat leukocyte nuclei) and anomalously proliferating (the human cervical adenocarcinoma cell line HeLa and the Chinese hamster fibroblast cell line A238) cells has been investigated using small-angle neutron scattering. The experimental results obtained allow one to make the inference that the parameters of the nucleosome structure for the chicken erythrocyte and rat leukocyte nuclei (on average over the nucleus) are close to the universally accepted values and that the distance distribution function is bimodal. The bimodality of the distance distribution function reflects a narrow distribution of distances between nucleosomes (on average over the nucleus) at the fibril level of the chromatin organization. The histone core of the nucleosome structure in the nuclei of the HeLa and A238 cells (on average over the nucleus) is considerably less compact than that in the chicken erythrocyte and rat leukocyte nuclei, and the distance distribution function does not exhibit indications of the bimodality. © 2010 Pleiades Publishing, Ltd.
@ARTICLE{Isaev-Ivanov20101063,
author={Isaev-Ivanov, V.V. and Lebedev, D.V. and Lauter, H. and Pantina, R.A. and Kuklin, A.I. and Islamov, A.K. and Filatov, M.V.},
title={Comparative analysis of the nucleosome structure of cell nuclei by small-angle neutron scattering},
journal={Physics of the Solid State},
year={2010},
volume={52},
number={5},
pages={1063-1073},
doi={10.1134/S1063783410050379},
note={cited By 4},
url={https://www.scopus.com/inward/record.uri?eid=2-s2.0-77952334920&doi=10.1134%2fS1063783410050379&partnerID=40&md5=b7266c4aa86093bcd4dc258952790714},
affiliation={Konstantinov Petersburg Nuclear Physics Institute, Russian Academy of Sciences, ul. Orlova Roshcha 1, Gatchina, Leningradskaya oblast 188300, Russian Federation; Research and Educational Center Biophysics of the St. Petersburg State Polytechnical University, Konstantinov Petersburg Nuclear Physics Institute of the Russian Academy of Sciences, St. Petersburg 195251, Russian Federation; Institut Laue-Langevin, BP 156, Grenoble 38042, France; Joint Institute for Nuclear Research, ul. Joliot-Curie 6, Dubna, Moscow oblast 141980, Russian Federation},
abstract={The nucleosome structure in native nuclei of normal (chicken erythrocyte and rat leukocyte nuclei) and anomalously proliferating (the human cervical adenocarcinoma cell line HeLa and the Chinese hamster fibroblast cell line A238) cells has been investigated using small-angle neutron scattering. The experimental results obtained allow one to make the inference that the parameters of the nucleosome structure for the chicken erythrocyte and rat leukocyte nuclei (on average over the nucleus) are close to the universally accepted values and that the distance distribution function is bimodal. The bimodality of the distance distribution function reflects a narrow distribution of distances between nucleosomes (on average over the nucleus) at the fibril level of the chromatin organization. The histone core of the nucleosome structure in the nuclei of the HeLa and A238 cells (on average over the nucleus) is considerably less compact than that in the chicken erythrocyte and rat leukocyte nuclei, and the distance distribution function does not exhibit indications of the bimodality. © 2010 Pleiades Publishing, Ltd.},
correspondence_address1={Filatov, M. V.; Konstantinov Petersburg Nuclear Physics Institute, Russian Academy of Sciences, ul. Orlova Roshcha 1, Gatchina, Leningradskaya oblast 188300, Russian Federation; email: filatov@omrb.pnpi.spb.ru},
issn={10637834},
language={English},
abbrev_source_title={Phys. Solid State},
document_type={Article},
source={Scopus},
}

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