Immunological correlates of the HIV-1 replication-competent reservoir size. Ismail, S. D, Riou, C., Joseph, S. B, Archin, N. M, Margolis, D. M, Perelson, A. S, Cassidy, T., Abrahams, M., Moeser, M., Council, O. D, McKinnon, L. R, Osman, F., Abdool Karim, Q., Abdool Karim, S. S, Swanstrom, R., Williamson, C., Garrett, N. J, & Burgers, W. A Clinical Infectious Diseases, 73(8):1528–1531, jun, 2021.
Paper doi abstract bibtex Understanding what shapes the latent HIV-1 reservoir is critical for developing strategies for cure. We measured the frequency of persistent HIV-1 infection after 5 years of suppressive antiretroviral therapy initiated during chronic infection. Pre-treatment CD8 + T-cell activation, nadir CD4 count, and CD4:CD8 ratio predicted reservoir size.
@article{Ismail2021,
abstract = {Understanding what shapes the latent HIV-1 reservoir is critical for developing strategies for cure. We measured the frequency of persistent HIV-1 infection after 5 years of suppressive antiretroviral therapy initiated during chronic infection. Pre-treatment CD8 + T-cell activation, nadir CD4 count, and CD4:CD8 ratio predicted reservoir size.},
author = {Ismail, Sherazaan D and Riou, Catherine and Joseph, Sarah B and Archin, Nancie M and Margolis, David M and Perelson, Alan S and Cassidy, Tyler and Abrahams, Melissa-Rose and Moeser, Matthew and Council, Olivia D and McKinnon, Lyle R and Osman, Farzana and {Abdool Karim}, Quarraisha and {Abdool Karim}, Salim S and Swanstrom, Ronald and Williamson, Carolyn and Garrett, Nigel J and Burgers, Wendy A},
doi = {10.1093/CID/CIAB587},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Ismail et al. - 2021 - Immunological correlates of the HIV-1 replication-competent reservoir size.pdf:pdf},
journal = {Clinical Infectious Diseases},
keywords = {OA,cd4/cd8 ratio procedure,fund{\_}ack,hiv-1 infection,original,t-cell activation,viruses},
mendeley-tags = {OA,fund{\_}ack,original},
month = {jun},
number = {8},
pages = {1528--1531},
pmid = {34181706},
title = {{Immunological correlates of the HIV-1 replication-competent reservoir size}},
url = {https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab587/6310797},
volume = {73},
year = {2021}
}
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