Functional neuroimaging provides evidence of anomalous cerebral laterality in adults with Klinefelter's syndrome

Functional neuroimaging provides evidence of anomalous cerebral laterality in adults with Klinefelter's syndrome. Itti, E., Gonzalo, I. T.<nbsp>G., Boone, K. B., Geschwind, D. H., Berman, N., Pawlikowska-Haddal, A., Itti, L., Mishkin, F. S., & Swerdloff, R. S. Annals of Neurology, 54(5):669-673, Department of Nuclear Medicine, Harbor-UCLA Medical Center, Research and Education Institute, Torrance, CA., Nov, 2003.
abstract bibtex

This study aimed to characterize cerebral perfusion in men with Klinefelter's syndrome, known to present specific deficits in language, using (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach normalization. While a perfusion asymmetry toward the left hemisphere was found in controls, perfusion was mostly symmetrical in Klinefelter patients in the upper temporal and lower parietal areas. Scores on verbal tests were inversely correlated with perfusion changes, providing neurobiological substrate of anomalous cerebral laterality.

@article{ Itti_etal03an,
  author = {E. Itti and I. T. Gaw Gonzalo and K. B. Boone and D. H. Geschwind
and N. Berman and A. Pawlikowska-Haddal and L. Itti and F. S. Mishkin and
R. S. Swerdloff},
  title = {Functional neuroimaging provides evidence of anomalous cerebral
laterality in adults with Klinefelter's syndrome},
  journal = {Annals of Neurology},
  volume = {54},
  number = {5},
  pages = {669-673},
  month = {Nov},
  year = {2003},
  abstract = {This study aimed to characterize cerebral perfusion in men with
Klinefelter's syndrome, known to present specific deficits in language,
using (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach
normalization. While a perfusion asymmetry toward the left hemisphere was
found in controls, perfusion was mostly symmetrical in Klinefelter patients
in the upper temporal and lower parietal areas. Scores on verbal tests were
inversely correlated with perfusion changes, providing neurobiological
substrate of anomalous cerebral laterality.},
  keywords = {},
  address = {Department of Nuclear Medicine, Harbor-UCLA Medical Center, Research
and Education Institute, Torrance, CA.},
  note = {},
  type = { med },
  file = { http://iLab.usc.edu/publications/doc/Itti_etal03an.pdf },
  if = {2002 impact factor: 8.603}
}

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{"_id":{"_str":"5298a1a19eb585cc260008fc"},"__v":0,"authorIDs":[],"author_short":["Itti, E.","Gonzalo, I.<nbsp>T.<nbsp>G.","Boone, K.<nbsp>B.","Geschwind, D.<nbsp>H.","Berman, N.","Pawlikowska-Haddal, A.","Itti, L.","Mishkin, F.<nbsp>S.","Swerdloff, R.<nbsp>S."],"bibbaseid":"itti-gonzalo-boone-geschwind-berman-pawlikowskahaddal-itti-mishkin-swerdloff-functionalneuroimagingprovidesevidenceofanomalouscerebrallateralityinadultswithklinefelterssyndrome-2003","bibdata":{"html":"<div class=\"bibbase_paper\"> \n\n\n<span class=\"bibbase_paper_titleauthoryear\">\n\t<span class=\"bibbase_paper_title\"><a name=\"Itti_etal03an\"> </a>Functional neuroimaging provides evidence of anomalous cerebral laterality in adults with Klinefelter's syndrome.</span>\n\t<span class=\"bibbase_paper_author\">\nItti, E.; Gonzalo, I. T.<nbsp>G.; Boone, K. B.; Geschwind, D. H.; Berman, N.; Pawlikowska-Haddal, A.; Itti, L.; Mishkin, F. S.; and Swerdloff, R. S.</span>\n\t\n</span>\n\n\n\n<i>Annals of Neurology</i>,\n\n54(5):669-673.\n\nNov 2003.\n\n\n\n\n<br class=\"bibbase_paper_content\"/>\n\n<span class=\"bibbase_paper_content\">\n \n \n \n <a href=\"javascript:showBib('Itti_etal03an')\"\n class=\"bibbase link\">\n \n\t\n\t\n\t\n BibTeX\n <i class=\"fa fa-caret-down\"></i></a>\n \n \n  \n <a class=\"bibbase_abstract_link bibbase link\"\n href=\"javascript:showAbstract('Itti_etal03an')\">\n Abstract\n <i class=\"fa fa-caret-down\"></i></a>\n \n \n \n\n \n \n \n</span>\n\n<div class=\"well well-small bibbase\" id=\"bib_Itti_etal03an\"\n style=\"display:none\">\n <pre>@article{ Itti_etal03an,\n author = {E. Itti and I. T. Gaw Gonzalo and K. B. Boone and D. H. Geschwind\nand N. Berman and A. Pawlikowska-Haddal and L. Itti and F. S. Mishkin and\nR. S. Swerdloff},\n title = {Functional neuroimaging provides evidence of anomalous cerebral\nlaterality in adults with Klinefelter's syndrome},\n journal = {Annals of Neurology},\n volume = {54},\n number = {5},\n pages = {669-673},\n month = {Nov},\n year = {2003},\n abstract = {This study aimed to characterize cerebral perfusion in men with\nKlinefelter's syndrome, known to present specific deficits in language,\nusing (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach\nnormalization. While a perfusion asymmetry toward the left hemisphere was\nfound in controls, perfusion was mostly symmetrical in Klinefelter patients\nin the upper temporal and lower parietal areas. Scores on verbal tests were\ninversely correlated with perfusion changes, providing neurobiological\nsubstrate of anomalous cerebral laterality.},\n keywords = {},\n address = {Department of Nuclear Medicine, Harbor-UCLA Medical Center, Research\nand Education Institute, Torrance, CA.},\n note = {},\n type = { med },\n file = { http://iLab.usc.edu/publications/doc/Itti_etal03an.pdf },\n if = {2002 impact factor: 8.603}\n}</pre>\n</div>\n\n\n<div class=\"well well-small bibbase\" id=\"abstract_Itti_etal03an\"\n style=\"display:none\">\n This study aimed to characterize cerebral perfusion in men with Klinefelter's syndrome, known to present specific deficits in language, using (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach normalization. While a perfusion asymmetry toward the left hemisphere was found in controls, perfusion was mostly symmetrical in Klinefelter patients in the upper temporal and lower parietal areas. Scores on verbal tests were inversely correlated with perfusion changes, providing neurobiological substrate of anomalous cerebral laterality.\n</div>\n\n\n</div>\n","downloads":0,"bibbaseid":"itti-gonzalo-boone-geschwind-berman-pawlikowskahaddal-itti-mishkin-swerdloff-functionalneuroimagingprovidesevidenceofanomalouscerebrallateralityinadultswithklinefelterssyndrome-2003","role":"author","year":"2003","volume":"54","type":"med","title":"Functional neuroimaging provides evidence of anomalous cerebral laterality in adults with Klinefelter's syndrome","pages":"669-673","number":"5","note":"","month":"Nov","keywords":"","key":"Itti_etal03an","journal":"Annals of Neurology","if":"2002 impact factor: 8.603","id":"Itti_etal03an","file":"http://iLab.usc.edu/publications/doc/Itti_etal03an.pdf","bibtype":"article","bibtex":"@article{ Itti_etal03an,\n author = {E. Itti and I. T. Gaw Gonzalo and K. B. Boone and D. H. Geschwind\nand N. Berman and A. Pawlikowska-Haddal and L. Itti and F. S. Mishkin and\nR. S. Swerdloff},\n title = {Functional neuroimaging provides evidence of anomalous cerebral\nlaterality in adults with Klinefelter's syndrome},\n journal = {Annals of Neurology},\n volume = {54},\n number = {5},\n pages = {669-673},\n month = {Nov},\n year = {2003},\n abstract = {This study aimed to characterize cerebral perfusion in men with\nKlinefelter's syndrome, known to present specific deficits in language,\nusing (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach\nnormalization. While a perfusion asymmetry toward the left hemisphere was\nfound in controls, perfusion was mostly symmetrical in Klinefelter patients\nin the upper temporal and lower parietal areas. Scores on verbal tests were\ninversely correlated with perfusion changes, providing neurobiological\nsubstrate of anomalous cerebral laterality.},\n keywords = {},\n address = {Department of Nuclear Medicine, Harbor-UCLA Medical Center, Research\nand Education Institute, Torrance, CA.},\n note = {},\n type = { med },\n file = { http://iLab.usc.edu/publications/doc/Itti_etal03an.pdf },\n if = {2002 impact factor: 8.603}\n}","author_short":["Itti, E.","Gonzalo, I.<nbsp>T.<nbsp>G.","Boone, K.<nbsp>B.","Geschwind, D.<nbsp>H.","Berman, N.","Pawlikowska-Haddal, A.","Itti, L.","Mishkin, F.<nbsp>S.","Swerdloff, R.<nbsp>S."],"author":["Itti, E.","Gonzalo, I. T. Gaw","Boone, K. B.","Geschwind, D. H.","Berman, N.","Pawlikowska-Haddal, A.","Itti, L.","Mishkin, F. S.","Swerdloff, R. S."],"address":"Department of Nuclear Medicine, Harbor-UCLA Medical Center, Research and Education Institute, Torrance, CA.","abstract":"This study aimed to characterize cerebral perfusion in men with Klinefelter's syndrome, known to present specific deficits in language, using (99m)Tc- hexamethylpropylene-amine-oxime scintigraphy and Talairach normalization. While a perfusion asymmetry toward the left hemisphere was found in controls, perfusion was mostly symmetrical in Klinefelter patients in the upper temporal and lower parietal areas. 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