Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields

Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields. Ivancsits, S., Diem, E., Jahn, O., & Rüdiger, H. W. Mechanisms of Ageing and Development, 2003.
doi abstract bibtex

Several studies indicating a decline of DNA repair efficiency with age raise the question, if senescence per se leads to a higher susceptibility to DNA damage upon environmental exposures. Cultured fibroblasts of six healthy donors of different age exposed to intermittent ELF-EMF (50 Hz sinus, 1 mT) for 1-24 h exhibited different basal DNA strand break levels correlating with age. The cells revealed a maximum response at 15-19 h of exposure. This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks. © 2003 Elsevier Science Ireland Ltd. All rights reserved.

@article{Ivancsits2003,
abstract = {Several studies indicating a decline of DNA repair efficiency with age raise the question, if senescence per se leads to a higher susceptibility to DNA damage upon environmental exposures. Cultured fibroblasts of six healthy donors of different age exposed to intermittent ELF-EMF (50 Hz sinus, 1 mT) for 1-24 h exhibited different basal DNA strand break levels correlating with age. The cells revealed a maximum response at 15-19 h of exposure. This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks. {\textcopyright} 2003 Elsevier Science Ireland Ltd. All rights reserved.},
author = {Ivancsits, Sabine and Diem, Elisabeth and Jahn, Oswald and R{\"{u}}diger, Hugo W.},
doi = {10.1016/S0047-6374(03)00125-8},
issn = {00476374},
journal = {Mechanisms of Ageing and Development},
keywords = {Ageing,Comet assay,ELF-EMF exposure,Fibroblasts},
pmid = {12875748},
title = {{Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields}},
year = {2003}
}

Downloads: 0

{"_id":"GkMhnAkYj7hKoSirS","bibbaseid":"ivancsits-diem-jahn-rdiger-agerelatedeffectsoninductionofdnastrandbreaksbyintermittentexposuretoelectromagneticfields-2003","author_short":["Ivancsits, S.","Diem, E.","Jahn, O.","Rüdiger, H. W."],"bibdata":{"bibtype":"article","type":"article","abstract":"Several studies indicating a decline of DNA repair efficiency with age raise the question, if senescence per se leads to a higher susceptibility to DNA damage upon environmental exposures. Cultured fibroblasts of six healthy donors of different age exposed to intermittent ELF-EMF (50 Hz sinus, 1 mT) for 1-24 h exhibited different basal DNA strand break levels correlating with age. The cells revealed a maximum response at 15-19 h of exposure. This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks. © 2003 Elsevier Science Ireland Ltd. All rights reserved.","author":[{"propositions":[],"lastnames":["Ivancsits"],"firstnames":["Sabine"],"suffixes":[]},{"propositions":[],"lastnames":["Diem"],"firstnames":["Elisabeth"],"suffixes":[]},{"propositions":[],"lastnames":["Jahn"],"firstnames":["Oswald"],"suffixes":[]},{"propositions":[],"lastnames":["Rüdiger"],"firstnames":["Hugo","W."],"suffixes":[]}],"doi":"10.1016/S0047-6374(03)00125-8","issn":"00476374","journal":"Mechanisms of Ageing and Development","keywords":"Ageing,Comet assay,ELF-EMF exposure,Fibroblasts","pmid":"12875748","title":"Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields","year":"2003","bibtex":"@article{Ivancsits2003,\nabstract = {Several studies indicating a decline of DNA repair efficiency with age raise the question, if senescence per se leads to a higher susceptibility to DNA damage upon environmental exposures. Cultured fibroblasts of six healthy donors of different age exposed to intermittent ELF-EMF (50 Hz sinus, 1 mT) for 1-24 h exhibited different basal DNA strand break levels correlating with age. The cells revealed a maximum response at 15-19 h of exposure. This response was clearly more pronounced in cells from older donors, which could point to an age-related decrease of DNA repair efficiency of ELF-EMF induced DNA strand breaks. {\\textcopyright} 2003 Elsevier Science Ireland Ltd. All rights reserved.},\nauthor = {Ivancsits, Sabine and Diem, Elisabeth and Jahn, Oswald and R{\\\"{u}}diger, Hugo W.},\ndoi = {10.1016/S0047-6374(03)00125-8},\nissn = {00476374},\njournal = {Mechanisms of Ageing and Development},\nkeywords = {Ageing,Comet assay,ELF-EMF exposure,Fibroblasts},\npmid = {12875748},\ntitle = {{Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields}},\nyear = {2003}\n}\n","author_short":["Ivancsits, S.","Diem, E.","Jahn, O.","Rüdiger, H. W."],"key":"Ivancsits2003","id":"Ivancsits2003","bibbaseid":"ivancsits-diem-jahn-rdiger-agerelatedeffectsoninductionofdnastrandbreaksbyintermittentexposuretoelectromagneticfields-2003","role":"author","urls":{},"keyword":["Ageing","Comet assay","ELF-EMF exposure","Fibroblasts"],"metadata":{"authorlinks":{}},"downloads":0,"html":""},"bibtype":"article","biburl":"https://bibbase.org/network/files/ChjuT9PC4NJ7R6xJc","dataSources":["gpCKn4jBfpcFxtxyi"],"keywords":["ageing","comet assay","elf-emf exposure","fibroblasts"],"search_terms":["age","related","effects","induction","dna","strand","breaks","intermittent","exposure","electromagnetic","fields","ivancsits","diem","jahn","rüdiger"],"title":"Age-related effects on induction of DNA strand breaks by intermittent exposure to electromagnetic fields","year":2003}