@article{ jacobi_p-anca_2005,
  title = {P-{ANCA} cranial pachymeningitis: a case report},
  volume = {24},
  issn = {0770-3198},
  shorttitle = {P-{ANCA} cranial pachymeningitis},
  doi = {10.1007/s10067-004-1022-4},
  abstract = {Pachymeningitis is an inflammatory process that thickens the dura mater. This disease has various etiologies including infectious, neoplastic, or autoimmune diseases. We present the case of a patient who developed cranial pachymeningitis with a clinical and biological picture suggestive of a neurological form of vasculitis. A 51-year-old woman developed rhinitis, otitis media, headaches, and deterioration of her condition after a course of recombinant hepatitis B vaccine. After a booster dose of the vaccine, she developed unilateral visual loss and impairment of multiple cranial nerves. Blood analysis showed inflammation and presence of antimyeloperoxidase antineutrophil cytoplasmic antibody ({MPO}-{ANCA}). Cranial magnetic resonance imaging ({MRI}) showed pachymeningitis. A complete remission was obtained with immunosuppressive therapy. The initial clinical presentation and subsequent remission under immunosuppressive therapy were suggestive of a vasculitis with nervous system involvement. Though vasculitis was not proven histologically in this patient, we believe that {MPO}-{ANCA}-related autoimmunity provoked the patient's disease as already reported in similar cases. As pachymeningitis is a fibrosing process, early recognition and treatment of an autoimmune etiology, even in the absence of previous pulmonary or renal involvement, is required to prevent definitive neurological impairment.},
  language = {eng},
  number = {2},
  journal = {Clinical Rheumatology},
  author = {Jacobi, D. and Maillot, F. and Hommet, C. and Arsène, S. and Cottier, J. P. and Lamisse, F. and Guillevin, L.},
  month = {April},
  year = {2005},
  pmid = {15578248},
  keywords = {Antibodies, Antineutrophil Cytoplasmic, Dura Mater, Female, Humans, Magnetic Resonance Imaging, Meningitis, Middle Aged, Peroxidase, Vasculitis, Central Nervous System},
  pages = {174--177}
}

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Blood analysis showed inflammation and presence of antimyeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA). Cranial magnetic resonance imaging (MRI) showed pachymeningitis. A complete remission was obtained with immunosuppressive therapy. The initial clinical presentation and subsequent remission under immunosuppressive therapy were suggestive of a vasculitis with nervous system involvement. Though vasculitis was not proven histologically in this patient, we believe that MPO-ANCA-related autoimmunity provoked the patient's disease as already reported in similar cases. As pachymeningitis is a fibrosing process, early recognition and treatment of an autoimmune etiology, even in the absence of previous pulmonary or renal involvement, is required to prevent definitive neurological impairment.","author":["Jacobi, D.","Maillot, F.","Hommet, C.","Arsène, S.","Cottier, J. P.","Lamisse, F.","Guillevin, L."],"author_short":["Jacobi, D.","Maillot, F.","Hommet, C.","Arsène, S.","Cottier, J.<nbsp>P.","Lamisse, F.","Guillevin, L."],"bibtex":"@article{ jacobi_p-anca_2005,\n title = {P-{ANCA} cranial pachymeningitis: a case report},\n volume = {24},\n issn = {0770-3198},\n shorttitle = {P-{ANCA} cranial pachymeningitis},\n doi = {10.1007/s10067-004-1022-4},\n abstract = {Pachymeningitis is an inflammatory process that thickens the dura mater. This disease has various etiologies including infectious, neoplastic, or autoimmune diseases. We present the case of a patient who developed cranial pachymeningitis with a clinical and biological picture suggestive of a neurological form of vasculitis. A 51-year-old woman developed rhinitis, otitis media, headaches, and deterioration of her condition after a course of recombinant hepatitis B vaccine. After a booster dose of the vaccine, she developed unilateral visual loss and impairment of multiple cranial nerves. Blood analysis showed inflammation and presence of antimyeloperoxidase antineutrophil cytoplasmic antibody ({MPO}-{ANCA}). Cranial magnetic resonance imaging ({MRI}) showed pachymeningitis. A complete remission was obtained with immunosuppressive therapy. The initial clinical presentation and subsequent remission under immunosuppressive therapy were suggestive of a vasculitis with nervous system involvement. Though vasculitis was not proven histologically in this patient, we believe that {MPO}-{ANCA}-related autoimmunity provoked the patient's disease as already reported in similar cases. As pachymeningitis is a fibrosing process, early recognition and treatment of an autoimmune etiology, even in the absence of previous pulmonary or renal involvement, is required to prevent definitive neurological impairment.},\n language = {eng},\n number = {2},\n journal = {Clinical Rheumatology},\n author = {Jacobi, D. and Maillot, F. and Hommet, C. and Arsène, S. and Cottier, J. 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