Serial monitoring of reverse left-atrial remodeling after pulmonary vein isolation in patients with atrial fibrillation: A magnetic resonance imaging study. Jahnke, C., Fischer, J., Gerds-Li, J., Gebker, R., Manka, R., Fleck, E., Paetsch, I., & Kriatselis, C. Int J Cardiol, (in press), 2011. bibtex @Article{RSM:Jah2011,
author = "C. Jahnke and J. Fischer and J.H. Gerds-Li and R. Gebker
and R. Manka and E. Fleck and I. Paetsch and C. Kriatselis",
title = "Serial monitoring of reverse left-atrial remodeling after
pulmonary vein isolation in patients with atrial
fibrillation: A magnetic resonance imaging study.",
journal = "Int J Cardiol",
year = "2011",
volume = "(in press)",
pages = "",
robnote = "PURPOSE: To prospectively determine the impact of sinus
rhythm restoration on left-atrial (LA) volumes and
function assessed by cardiac magnetic resonance (CMR)
imaging within the first year after pulmonary vein
isolation (PVI). METHODS: Forty-one patients (28 men; age:
57+/-10years) with paroxysmal or non-paroxysmal atrial
fibrillation were studied serially using CMR at baseline
and at 1-, 3-, 6- and 12-month intervals following PVI. LA
diastolic and systolic volumes were determined by cine
imaging with full gapless LA coverage applying Simpson's
rule. Successful PVI was defined by a persisting sinus
rhythm during the 12-month follow-up after a 3-month
blanking period; patients with a relapse of atrial
fibrillation after the blanking period were censored (4
patients at 6-month follow-up and additional 6 patients at
12-month follow-up). RESULTS: In all patients, LA
diastolic and systolic volumes decreased significantly and
progressively during the 12-month follow-up (p<0.001 and
p=0.001, respectively). At basegline patients with
successful PVI demonstrated a significantly smaller LA
diastolic volume compared to patients with relapsed atrial
fibrillation (p=0.009). During the 3-month blanking
period, patients with successful PVI showed a significant
decrease of LA diastolic and systolic volumes (p=0.026 and
p=0.006, respectively) and a significant increase of LA
ejection fraction (p=0.028); patients with subsequent
relapse of atrial fibrillation, however, exhibited no
significant change of LA diastolic and systolic volumes or
LA ejection fraction. CONCLUSION: Restoration of sinus
rhythm led to a significant and progressive decrease of
left-atrial diastolic and systolic volumes during one year
following pulmonary vein isolation.",
bibdate = "Wed Aug 3 07:10:47 2011",
}
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METHODS: Forty-one patients (28 men; age: 57+/-10years) with paroxysmal or non-paroxysmal atrial fibrillation were studied serially using CMR at baseline and at 1-, 3-, 6- and 12-month intervals following PVI. LA diastolic and systolic volumes were determined by cine imaging with full gapless LA coverage applying Simpson's rule. Successful PVI was defined by a persisting sinus rhythm during the 12-month follow-up after a 3-month blanking period; patients with a relapse of atrial fibrillation after the blanking period were censored (4 patients at 6-month follow-up and additional 6 patients at 12-month follow-up). RESULTS: In all patients, LA diastolic and systolic volumes decreased significantly and progressively during the 12-month follow-up (p<0.001 and p=0.001, respectively). At basegline patients with successful PVI demonstrated a significantly smaller LA diastolic volume compared to patients with relapsed atrial fibrillation (p=0.009). During the 3-month blanking period, patients with successful PVI showed a significant decrease of LA diastolic and systolic volumes (p=0.026 and p=0.006, respectively) and a significant increase of LA ejection fraction (p=0.028); patients with subsequent relapse of atrial fibrillation, however, exhibited no significant change of LA diastolic and systolic volumes or LA ejection fraction. CONCLUSION: Restoration of sinus rhythm led to a significant and progressive decrease of left-atrial diastolic and systolic volumes during one year following pulmonary vein isolation.","bibdate":"Wed Aug 3 07:10:47 2011","bibtex":"@Article{RSM:Jah2011,\n author = \"C. Jahnke and J. Fischer and J.H. Gerds-Li and R. Gebker\n and R. Manka and E. Fleck and I. Paetsch and C. Kriatselis\",\n title = \"Serial monitoring of reverse left-atrial remodeling after\n pulmonary vein isolation in patients with atrial\n fibrillation: A magnetic resonance imaging study.\",\n journal = \"Int J Cardiol\",\n year = \"2011\",\n volume = \"(in press)\",\n pages = \"\",\n robnote = \"PURPOSE: To prospectively determine the impact of sinus\n rhythm restoration on left-atrial (LA) volumes and\n function assessed by cardiac magnetic resonance (CMR)\n imaging within the first year after pulmonary vein\n isolation (PVI). METHODS: Forty-one patients (28 men; age:\n 57+/-10years) with paroxysmal or non-paroxysmal atrial\n fibrillation were studied serially using CMR at baseline\n and at 1-, 3-, 6- and 12-month intervals following PVI. LA\n diastolic and systolic volumes were determined by cine\n imaging with full gapless LA coverage applying Simpson's\n rule. Successful PVI was defined by a persisting sinus\n rhythm during the 12-month follow-up after a 3-month\n blanking period; patients with a relapse of atrial\n fibrillation after the blanking period were censored (4\n patients at 6-month follow-up and additional 6 patients at\n 12-month follow-up). RESULTS: In all patients, LA\n diastolic and systolic volumes decreased significantly and\n progressively during the 12-month follow-up (p<0.001 and\n p=0.001, respectively). At basegline patients with\n successful PVI demonstrated a significantly smaller LA\n diastolic volume compared to patients with relapsed atrial\n fibrillation (p=0.009). During the 3-month blanking\n period, patients with successful PVI showed a significant\n decrease of LA diastolic and systolic volumes (p=0.026 and\n p=0.006, respectively) and a significant increase of LA\n ejection fraction (p=0.028); patients with subsequent\n relapse of atrial fibrillation, however, exhibited no\n significant change of LA diastolic and systolic volumes or\n LA ejection fraction. CONCLUSION: Restoration of sinus\n rhythm led to a significant and progressive decrease of\n left-atrial diastolic and systolic volumes during one year\n following pulmonary vein isolation.\",\n bibdate = \"Wed Aug 3 07:10:47 2011\",\n}\n\n","author_short":["Jahnke, C.","Fischer, J.","Gerds-Li, J.","Gebker, R.","Manka, R.","Fleck, E.","Paetsch, I.","Kriatselis, C."],"key":"RSM:Jah2011","id":"RSM:Jah2011","bibbaseid":"jahnke-fischer-gerdsli-gebker-manka-fleck-paetsch-kriatselis-serialmonitoringofreverseleftatrialremodelingafterpulmonaryveinisolationinpatientswithatrialfibrillationamagneticresonanceimagingstudy-2011","role":"author","urls":{},"downloads":0,"html":""},"search_terms":["serial","monitoring","reverse","left","atrial","remodeling","pulmonary","vein","isolation","patients","atrial","fibrillation","magnetic","resonance","imaging","study","jahnke","fischer","gerds-li","gebker","manka","fleck","paetsch","kriatselis"],"keywords":[],"authorIDs":[],"dataSources":["5HG3Kp8zRwDd7FotB"]}