Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy. Jansen, J. F., Aldenkamp, A. P., Marian Majoie, H. J., Reijs, R. P., de Krom, M. C., Hofman, P. A., Eline Kooi, M., Nicolay, K., & Backes, W. H. Epilepsy Behav, 9(1):181-5, 2006. Jansen, Jacobus F A Aldenkamp, Albert P Marian Majoie, H J Reijs, Rianne P de Krom, Marc C T F M Hofman, Paul A M Eline Kooi, M Nicolay, Klaas Backes, Walter H eng 2006/06/24 09:00 Epilepsy Behav. 2006 Aug;9(1):181-5. doi: 10.1016/j.yebeh.2006.05.004. Epub 2006 Jun 21.
Paper doi abstract bibtex Functional magnetic resonance imaging of covert word generation was used to examine brain activation abnormalities associated with topiramate-induced cognitive language impairment in patients with epilepsy. Compared with a control epilepsy group, in the topiramate-treated group, there was significantly less activation in the language-mediating regions of the prefrontal cortex; the topiramate group also had significantly lower neuropsychological language scores. These findings suggest that topiramate has a critical effect on the cerebral neural systems that mediate expressive language.
@article{RN124,
author = {Jansen, J. F. and Aldenkamp, A. P. and Marian Majoie, H. J. and Reijs, R. P. and de Krom, M. C. and Hofman, P. A. and Eline Kooi, M. and Nicolay, K. and Backes, W. H.},
title = {Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy},
journal = {Epilepsy Behav},
volume = {9},
number = {1},
pages = {181-5},
note = {Jansen, Jacobus F A
Aldenkamp, Albert P
Marian Majoie, H J
Reijs, Rianne P
de Krom, Marc C T F M
Hofman, Paul A M
Eline Kooi, M
Nicolay, Klaas
Backes, Walter H
eng
2006/06/24 09:00
Epilepsy Behav. 2006 Aug;9(1):181-5. doi: 10.1016/j.yebeh.2006.05.004. Epub 2006 Jun 21.},
abstract = {Functional magnetic resonance imaging of covert word generation was used to examine brain activation abnormalities associated with topiramate-induced cognitive language impairment in patients with epilepsy. Compared with a control epilepsy group, in the topiramate-treated group, there was significantly less activation in the language-mediating regions of the prefrontal cortex; the topiramate group also had significantly lower neuropsychological language scores. These findings suggest that topiramate has a critical effect on the cerebral neural systems that mediate expressive language.},
keywords = {Adult
Anticonvulsants/adverse effects/*pharmacology/therapeutic use
Cognition/drug effects
Epilepsy/drug therapy/*physiopathology
Female
Fructose/adverse effects/*analogs & derivatives/pharmacology/therapeutic use
Humans
Language Disorders/*chemically induced/physiopathology
Magnetic Resonance Imaging
Male
Neuropsychological Tests
Prefrontal Cortex/*drug effects/physiopathology
Topiramate},
ISSN = {1525-5050 (Print)
1525-5050 (Linking)},
DOI = {10.1016/j.yebeh.2006.05.004},
url = {http://www.ncbi.nlm.nih.gov/pubmed/16793345
https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/fulltext
https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/pdf},
year = {2006},
type = {Journal Article}
}
Downloads: 0
{"_id":"NM7TyCRFRCuvuQTSK","bibbaseid":"jansen-aldenkamp-marianmajoie-reijs-dekrom-hofman-elinekooi-nicolay-etal-functionalmrirevealsdeclinedprefrontalcortexactivationinpatientswithepilepsyontopiramatetherapy-2006","downloads":0,"creationDate":"2017-09-02T18:10:13.588Z","title":"Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy","author_short":["Jansen, J. F.","Aldenkamp, A. P.","Marian Majoie, H. J.","Reijs, R. P.","de Krom, M. C.","Hofman, P. A.","Eline Kooi, M.","Nicolay, K.","Backes, W. H."],"year":2006,"bibtype":"article","biburl":"https://raw.githubusercontent.com/jansenjfa1/bibbase.github.io/master/jansenjfa.bib","bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Jansen"],"firstnames":["J.","F."],"suffixes":[]},{"propositions":[],"lastnames":["Aldenkamp"],"firstnames":["A.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Marian","Majoie"],"firstnames":["H.","J."],"suffixes":[]},{"propositions":[],"lastnames":["Reijs"],"firstnames":["R.","P."],"suffixes":[]},{"propositions":["de"],"lastnames":["Krom"],"firstnames":["M.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Hofman"],"firstnames":["P.","A."],"suffixes":[]},{"propositions":[],"lastnames":["Eline","Kooi"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Nicolay"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Backes"],"firstnames":["W.","H."],"suffixes":[]}],"title":"Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy","journal":"Epilepsy Behav","volume":"9","number":"1","pages":"181-5","note":"Jansen, Jacobus F A Aldenkamp, Albert P Marian Majoie, H J Reijs, Rianne P de Krom, Marc C T F M Hofman, Paul A M Eline Kooi, M Nicolay, Klaas Backes, Walter H eng 2006/06/24 09:00 Epilepsy Behav. 2006 Aug;9(1):181-5. doi: 10.1016/j.yebeh.2006.05.004. Epub 2006 Jun 21.","abstract":"Functional magnetic resonance imaging of covert word generation was used to examine brain activation abnormalities associated with topiramate-induced cognitive language impairment in patients with epilepsy. Compared with a control epilepsy group, in the topiramate-treated group, there was significantly less activation in the language-mediating regions of the prefrontal cortex; the topiramate group also had significantly lower neuropsychological language scores. These findings suggest that topiramate has a critical effect on the cerebral neural systems that mediate expressive language.","keywords":"Adult Anticonvulsants/adverse effects/*pharmacology/therapeutic use Cognition/drug effects Epilepsy/drug therapy/*physiopathology Female Fructose/adverse effects/*analogs & derivatives/pharmacology/therapeutic use Humans Language Disorders/*chemically induced/physiopathology Magnetic Resonance Imaging Male Neuropsychological Tests Prefrontal Cortex/*drug effects/physiopathology Topiramate","issn":"1525-5050 (Print) 1525-5050 (Linking)","doi":"10.1016/j.yebeh.2006.05.004","url":"http://www.ncbi.nlm.nih.gov/pubmed/16793345 https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/fulltext https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/pdf","year":"2006","bibtex":"@article{RN124,\n author = {Jansen, J. F. and Aldenkamp, A. P. and Marian Majoie, H. J. and Reijs, R. P. and de Krom, M. C. and Hofman, P. A. and Eline Kooi, M. and Nicolay, K. and Backes, W. H.},\n title = {Functional MRI reveals declined prefrontal cortex activation in patients with epilepsy on topiramate therapy},\n journal = {Epilepsy Behav},\n volume = {9},\n number = {1},\n pages = {181-5},\n note = {Jansen, Jacobus F A\nAldenkamp, Albert P\nMarian Majoie, H J\nReijs, Rianne P\nde Krom, Marc C T F M\nHofman, Paul A M\nEline Kooi, M\nNicolay, Klaas\nBackes, Walter H\neng\n2006/06/24 09:00\nEpilepsy Behav. 2006 Aug;9(1):181-5. doi: 10.1016/j.yebeh.2006.05.004. Epub 2006 Jun 21.},\n abstract = {Functional magnetic resonance imaging of covert word generation was used to examine brain activation abnormalities associated with topiramate-induced cognitive language impairment in patients with epilepsy. Compared with a control epilepsy group, in the topiramate-treated group, there was significantly less activation in the language-mediating regions of the prefrontal cortex; the topiramate group also had significantly lower neuropsychological language scores. These findings suggest that topiramate has a critical effect on the cerebral neural systems that mediate expressive language.},\n keywords = {Adult\nAnticonvulsants/adverse effects/*pharmacology/therapeutic use\nCognition/drug effects\nEpilepsy/drug therapy/*physiopathology\nFemale\nFructose/adverse effects/*analogs & derivatives/pharmacology/therapeutic use\nHumans\nLanguage Disorders/*chemically induced/physiopathology\nMagnetic Resonance Imaging\nMale\nNeuropsychological Tests\nPrefrontal Cortex/*drug effects/physiopathology\nTopiramate},\n ISSN = {1525-5050 (Print)\n1525-5050 (Linking)},\n DOI = {10.1016/j.yebeh.2006.05.004},\n url = {http://www.ncbi.nlm.nih.gov/pubmed/16793345\nhttps://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/fulltext\nhttps://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/pdf},\n year = {2006},\n type = {Journal Article}\n}\n\n","author_short":["Jansen, J. F.","Aldenkamp, A. P.","Marian Majoie, H. J.","Reijs, R. P.","de Krom, M. C.","Hofman, P. A.","Eline Kooi, M.","Nicolay, K.","Backes, W. H."],"key":"RN124","id":"RN124","bibbaseid":"jansen-aldenkamp-marianmajoie-reijs-dekrom-hofman-elinekooi-nicolay-etal-functionalmrirevealsdeclinedprefrontalcortexactivationinpatientswithepilepsyontopiramatetherapy-2006","role":"author","urls":{"Paper":"http://www.ncbi.nlm.nih.gov/pubmed/16793345 https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/fulltext https://www.epilepsybehavior.com/article/S1525-5050(06)00183-1/pdf"},"keyword":["Adult Anticonvulsants/adverse effects/*pharmacology/therapeutic use Cognition/drug effects Epilepsy/drug therapy/*physiopathology Female Fructose/adverse effects/*analogs & derivatives/pharmacology/therapeutic use Humans Language Disorders/*chemically induced/physiopathology Magnetic Resonance Imaging Male Neuropsychological Tests Prefrontal Cortex/*drug effects/physiopathology Topiramate"],"metadata":{"authorlinks":{"jansen, j":"https://www.jansenjfa.com/publications/"}},"downloads":0,"html":""},"search_terms":["functional","mri","reveals","declined","prefrontal","cortex","activation","patients","epilepsy","topiramate","therapy","jansen","aldenkamp","marian majoie","reijs","de krom","hofman","eline kooi","nicolay","backes"],"keywords":["adult anticonvulsants/adverse effects/*pharmacology/therapeutic use cognition/drug effects epilepsy/drug therapy/*physiopathology female fructose/adverse effects/*analogs & derivatives/pharmacology/therapeutic use humans language disorders/*chemically induced/physiopathology magnetic resonance imaging male neuropsychological tests prefrontal cortex/*drug effects/physiopathology topiramate"],"authorIDs":["TEAWLnKpXtQE8hs6C"],"dataSources":["TCkfRWJAZvbLAZi29"]}