Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla. Jansen, J. F., Kooi, M. E., Kessels, A. G., Nicolay, K., & Backes, W. H. Invest Radiol, 42(6):327-37, 2007. Jansen, Jacobus F A Kooi, M Eline Kessels, Alfons G H Nicolay, Klaas Backes, Walter H eng Research Support, Non-U.S. Gov't 2007/05/18 09:00 Invest Radiol. 2007 Jun;42(6):327-37. doi: 10.1097/01.rli.0000262757.10271.e5.
Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla [link]Paper  doi  abstract   bibtex   
OBJECTIVES: The reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and H magnetic resonance (MR) spectroscopic imaging was assessed on a clinical 3.0 T MR system. MATERIALS AND METHODS: Repeated measurements in 10 healthy volunteers were used to establish the reproducibility of quantitative measures derived from different quantitative MR techniques, namely the T2 relaxation time, the apparent diffusion coefficient (ADC), the fractional anisotropy (FA), and metabolite concentrations of N-acetyl-aspartate (NAA), creatine (Cr), choline (Cho), and myo-inositol (mI). Results were compared with previously reported reproducibility measures from 1.5 T. RESULTS: The coefficient of variation (CV) was < or =1.6% for T2, < or =1.6% for ADC, and < or =5.3%, for FA in the cerebrum. For metabolites the CV was < or =8.0% in the frontal lobe and < or =20.4% in the temporal lobe. CONCLUSIONS: The reproducibility of quantitative brain MRI at 3.0 T is better than or at least comparable to the reproducibility at 1.5 T.
@article{RN127,
   author = {Jansen, J. F. and Kooi, M. E. and Kessels, A. G. and Nicolay, K. and Backes, W. H.},
   title = {Reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and 1H magnetic resonance spectroscopy at 3.0 Tesla},
   journal = {Invest Radiol},
   volume = {42},
   number = {6},
   pages = {327-37},
   note = {Jansen, Jacobus F A
Kooi, M Eline
Kessels, Alfons G H
Nicolay, Klaas
Backes, Walter H
eng
Research Support, Non-U.S. Gov't
2007/05/18 09:00
Invest Radiol. 2007 Jun;42(6):327-37. doi: 10.1097/01.rli.0000262757.10271.e5.},
   abstract = {OBJECTIVES: The reproducibility of quantitative cerebral T2 relaxometry, diffusion tensor imaging, and H magnetic resonance (MR) spectroscopic imaging was assessed on a clinical 3.0 T MR system. MATERIALS AND METHODS: Repeated measurements in 10 healthy volunteers were used to establish the reproducibility of quantitative measures derived from different quantitative MR techniques, namely the T2 relaxation time, the apparent diffusion coefficient (ADC), the fractional anisotropy (FA), and metabolite concentrations of N-acetyl-aspartate (NAA), creatine (Cr), choline (Cho), and myo-inositol (mI). Results were compared with previously reported reproducibility measures from 1.5 T. RESULTS: The coefficient of variation (CV) was < or =1.6% for T2, < or =1.6% for ADC, and < or =5.3%, for FA in the cerebrum. For metabolites the CV was < or =8.0% in the frontal lobe and < or =20.4% in the temporal lobe. CONCLUSIONS: The reproducibility of quantitative brain MRI at 3.0 T is better than or at least comparable to the reproducibility at 1.5 T.},
   keywords = {Adult
Anisotropy
Aspartic Acid/analogs & derivatives/metabolism
*Brain Chemistry
Brain Mapping/*methods
Choline/metabolism
Creatine/metabolism
Data Interpretation, Statistical
Diffusion Magnetic Resonance Imaging/*methods
Female
Humans
Image Processing, Computer-Assisted
Inositol/metabolism
Magnetic Resonance Spectroscopy/*methods
Male
Reference Values
Reproducibility of Results},
   ISSN = {0020-9996 (Print)
0020-9996 (Linking)},
   DOI = {10.1097/01.rli.0000262757.10271.e5},
   url = {http://www.ncbi.nlm.nih.gov/pubmed/17507802},
   year = {2007},
   type = {Journal Article}
}

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