Bone cancer pain. Jimenez-Andrade, J. M., Mantyh, W. G., Bloom, A. P., Ferng, A. S., Geffre, C. P., & Mantyh, P. W. Annals of the New York Academy of Sciences, 1198:173-181, Ann N Y Acad Sci, 2010. ![Bone cancer pain [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex In the United States, cancer is the second most common cause of death and it is expected that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is common in patients with advanced breast, prostate, and lung cancer as these tumors have a remarkable affinity to metastasize to bone. Once tumors metastasize to bone, they are a major cause of morbidity and mortality as the tumor induces significant skeletal remodeling, fractures, pain, and anemia. Currently, the factors that drive cancer pain are poorly understood. However, several recently introduced models of bone cancer pain, which closely mirror the human condition, are providing insight into the mechanisms that drive bone cancer pain and guide the development of mechanism-based therapies to treat the cancer pain. Several of these mechanism-based therapies have now entered human clinical trials. If successful, these therapies have the potential to significantly enlarge the repertoire of modalities that can be used to treat bone cancer pain and improve the quality of life, functional status, and survival of patients with bone cancer. © 2010 New York Academy of Sciences.
@article{,
abstract = {In the United States, cancer is the second most common cause of death and it is expected that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is common in patients with advanced breast, prostate, and lung cancer as these tumors have a remarkable affinity to metastasize to bone. Once tumors metastasize to bone, they are a major cause of morbidity and mortality as the tumor induces significant skeletal remodeling, fractures, pain, and anemia. Currently, the factors that drive cancer pain are poorly understood. However, several recently introduced models of bone cancer pain, which closely mirror the human condition, are providing insight into the mechanisms that drive bone cancer pain and guide the development of mechanism-based therapies to treat the cancer pain. Several of these mechanism-based therapies have now entered human clinical trials. If successful, these therapies have the potential to significantly enlarge the repertoire of modalities that can be used to treat bone cancer pain and improve the quality of life, functional status, and survival of patients with bone cancer. © 2010 New York Academy of Sciences.},
author = {Juan Miguel Jimenez-Andrade and William G. Mantyh and Aaron P. Bloom and Alice S. Ferng and Christopher P. Geffre and Patrick W. Mantyh},
doi = {10.1111/J.1749-6632.2009.05429.X},
isbn = {9781573317788},
issn = {1749-6632},
journal = {Annals of the New York Academy of Sciences},
keywords = {Acidosis / etiology,Animal,Animals,Bone Neoplasms / epidemiology,Bone Neoplasms / mortality,Bone Neoplasms / pathology,Bone Neoplasms / physiopathology*,Bone Neoplasms / secondary,Bone and Bones / pathology,Breast Neoplasms / complications,Disease Models,Female,Humans,Juan Miguel Jimenez-Andrade,Lung Neoplasms / complications,MEDLINE,Male,Mice,NCBI,NIH,NLM,National Center for Biotechnology Information,National Institutes of Health,National Library of Medicine,Neoplasm Metastasis / pathology,Osteoclasts / pathology,PMC5642911,Pain / etiology,Pain / physiopathology*,Patrick W Mantyh,Prostatic Neoplasms / complications,PubMed Abstract,Review,Sarcoma / pathology,United States / epidemiology,William G Mantyh,doi:10.1111/j.1749-6632.2009.05429.x,pmid:20536932},
pages = {173-181},
pmid = {20536932},
publisher = {Ann N Y Acad Sci},
title = {Bone cancer pain},
volume = {1198},
url = {https://pubmed.ncbi.nlm.nih.gov/20536932/},
year = {2010},
}
Downloads: 0
{"_id":"2KjvwBH8r7TzNDNmY","bibbaseid":"jimenezandrade-mantyh-bloom-ferng-geffre-mantyh-bonecancerpain-2010","author_short":["Jimenez-Andrade, J. M.","Mantyh, W. G.","Bloom, A. P.","Ferng, A. S.","Geffre, C. P.","Mantyh, P. W."],"bibdata":{"bibtype":"article","type":"article","abstract":"In the United States, cancer is the second most common cause of death and it is expected that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is common in patients with advanced breast, prostate, and lung cancer as these tumors have a remarkable affinity to metastasize to bone. Once tumors metastasize to bone, they are a major cause of morbidity and mortality as the tumor induces significant skeletal remodeling, fractures, pain, and anemia. Currently, the factors that drive cancer pain are poorly understood. However, several recently introduced models of bone cancer pain, which closely mirror the human condition, are providing insight into the mechanisms that drive bone cancer pain and guide the development of mechanism-based therapies to treat the cancer pain. Several of these mechanism-based therapies have now entered human clinical trials. If successful, these therapies have the potential to significantly enlarge the repertoire of modalities that can be used to treat bone cancer pain and improve the quality of life, functional status, and survival of patients with bone cancer. © 2010 New York Academy of Sciences.","author":[{"firstnames":["Juan","Miguel"],"propositions":[],"lastnames":["Jimenez-Andrade"],"suffixes":[]},{"firstnames":["William","G."],"propositions":[],"lastnames":["Mantyh"],"suffixes":[]},{"firstnames":["Aaron","P."],"propositions":[],"lastnames":["Bloom"],"suffixes":[]},{"firstnames":["Alice","S."],"propositions":[],"lastnames":["Ferng"],"suffixes":[]},{"firstnames":["Christopher","P."],"propositions":[],"lastnames":["Geffre"],"suffixes":[]},{"firstnames":["Patrick","W."],"propositions":[],"lastnames":["Mantyh"],"suffixes":[]}],"doi":"10.1111/J.1749-6632.2009.05429.X","isbn":"9781573317788","issn":"1749-6632","journal":"Annals of the New York Academy of Sciences","keywords":"Acidosis / etiology,Animal,Animals,Bone Neoplasms / epidemiology,Bone Neoplasms / mortality,Bone Neoplasms / pathology,Bone Neoplasms / physiopathology*,Bone Neoplasms / secondary,Bone and Bones / pathology,Breast Neoplasms / complications,Disease Models,Female,Humans,Juan Miguel Jimenez-Andrade,Lung Neoplasms / complications,MEDLINE,Male,Mice,NCBI,NIH,NLM,National Center for Biotechnology Information,National Institutes of Health,National Library of Medicine,Neoplasm Metastasis / pathology,Osteoclasts / pathology,PMC5642911,Pain / etiology,Pain / physiopathology*,Patrick W Mantyh,Prostatic Neoplasms / complications,PubMed Abstract,Review,Sarcoma / pathology,United States / epidemiology,William G Mantyh,doi:10.1111/j.1749-6632.2009.05429.x,pmid:20536932","pages":"173-181","pmid":"20536932","publisher":"Ann N Y Acad Sci","title":"Bone cancer pain","volume":"1198","url":"https://pubmed.ncbi.nlm.nih.gov/20536932/","year":"2010","bibtex":"@article{,\n abstract = {In the United States, cancer is the second most common cause of death and it is expected that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is common in patients with advanced breast, prostate, and lung cancer as these tumors have a remarkable affinity to metastasize to bone. Once tumors metastasize to bone, they are a major cause of morbidity and mortality as the tumor induces significant skeletal remodeling, fractures, pain, and anemia. Currently, the factors that drive cancer pain are poorly understood. However, several recently introduced models of bone cancer pain, which closely mirror the human condition, are providing insight into the mechanisms that drive bone cancer pain and guide the development of mechanism-based therapies to treat the cancer pain. Several of these mechanism-based therapies have now entered human clinical trials. If successful, these therapies have the potential to significantly enlarge the repertoire of modalities that can be used to treat bone cancer pain and improve the quality of life, functional status, and survival of patients with bone cancer. © 2010 New York Academy of Sciences.},\n author = {Juan Miguel Jimenez-Andrade and William G. Mantyh and Aaron P. Bloom and Alice S. Ferng and Christopher P. Geffre and Patrick W. Mantyh},\n doi = {10.1111/J.1749-6632.2009.05429.X},\n isbn = {9781573317788},\n issn = {1749-6632},\n journal = {Annals of the New York Academy of Sciences},\n keywords = {Acidosis / etiology,Animal,Animals,Bone Neoplasms / epidemiology,Bone Neoplasms / mortality,Bone Neoplasms / pathology,Bone Neoplasms / physiopathology*,Bone Neoplasms / secondary,Bone and Bones / pathology,Breast Neoplasms / complications,Disease Models,Female,Humans,Juan Miguel Jimenez-Andrade,Lung Neoplasms / complications,MEDLINE,Male,Mice,NCBI,NIH,NLM,National Center for Biotechnology Information,National Institutes of Health,National Library of Medicine,Neoplasm Metastasis / pathology,Osteoclasts / pathology,PMC5642911,Pain / etiology,Pain / physiopathology*,Patrick W Mantyh,Prostatic Neoplasms / complications,PubMed Abstract,Review,Sarcoma / pathology,United States / epidemiology,William G Mantyh,doi:10.1111/j.1749-6632.2009.05429.x,pmid:20536932},\n pages = {173-181},\n pmid = {20536932},\n publisher = {Ann N Y Acad Sci},\n title = {Bone cancer pain},\n volume = {1198},\n url = {https://pubmed.ncbi.nlm.nih.gov/20536932/},\n year = {2010},\n}\n","author_short":["Jimenez-Andrade, J. M.","Mantyh, W. G.","Bloom, A. P.","Ferng, A. S.","Geffre, C. P.","Mantyh, P. W."],"key":"-1-1-1-1-1","id":"-1-1-1-1-1","bibbaseid":"jimenezandrade-mantyh-bloom-ferng-geffre-mantyh-bonecancerpain-2010","role":"author","urls":{"Paper":"https://pubmed.ncbi.nlm.nih.gov/20536932/"},"keyword":["Acidosis / etiology","Animal","Animals","Bone Neoplasms / epidemiology","Bone Neoplasms / mortality","Bone Neoplasms / pathology","Bone Neoplasms / physiopathology*","Bone Neoplasms / secondary","Bone and Bones / pathology","Breast Neoplasms / complications","Disease Models","Female","Humans","Juan Miguel Jimenez-Andrade","Lung Neoplasms / complications","MEDLINE","Male","Mice","NCBI","NIH","NLM","National Center for Biotechnology Information","National Institutes of Health","National Library of Medicine","Neoplasm Metastasis / pathology","Osteoclasts / pathology","PMC5642911","Pain / etiology","Pain / physiopathology*","Patrick W Mantyh","Prostatic Neoplasms / complications","PubMed Abstract","Review","Sarcoma / pathology","United States / epidemiology","William G Mantyh","doi:10.1111/j.1749-6632.2009.05429.x","pmid:20536932"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/f/4ft99tZ6K9Gu64h6W/export.bib","dataSources":["FmcPshqQjF4qywijY","N6iMJ27vDKnqJ7SQx","zXSDrMxMkAGETxZND"],"keywords":["acidosis / etiology","animal","animals","bone neoplasms / epidemiology","bone neoplasms / mortality","bone neoplasms / pathology","bone neoplasms / physiopathology*","bone neoplasms / secondary","bone and bones / pathology","breast neoplasms / complications","disease models","female","humans","juan miguel jimenez-andrade","lung neoplasms / complications","medline","male","mice","ncbi","nih","nlm","national center for biotechnology information","national institutes of health","national library of medicine","neoplasm metastasis / pathology","osteoclasts / pathology","pmc5642911","pain / etiology","pain / physiopathology*","patrick w mantyh","prostatic neoplasms / complications","pubmed abstract","review","sarcoma / pathology","united states / epidemiology","william g mantyh","doi:10.1111/j.1749-6632.2009.05429.x","pmid:20536932"],"search_terms":["bone","cancer","pain","jimenez-andrade","mantyh","bloom","ferng","geffre","mantyh"],"title":"Bone cancer pain","year":2010}