Significance of autoantibodies to soluble liver antigen (SLA) in autoimmune hepatitis. Johanet, C. & Ballot, E. Immuno-analyse et biologie spécialisée, 26(3):118–124, January, 2011.
abstract   bibtex   
Antibody detection plays an important role in diagnosis and classification of autoimmune hepatitis. Antibodies to soluble liver antigen are considered to be a specific marker of type 1 autoimmune hepatitis. Their detection is of interest in patients who are negative for conventional markers of the disease (antinuclear antibodies and anti-smooth muscle antibodies reacting specifically against actin cables). Actually, these antibodies allow us to reclassify as type 1 autoimmune hepatitis, 15 to 20% of hepatitis regarded as cryptogenic. The pronostic value of antibodies to soluble liver antigen has seldom been studied and is controversial. They might be used to evaluate the risk of relapse of the inflammatory process after corticosteroid therapy and to recurrence of autoimmune hepatitis after orthotopic liver transplantation.
@article{johanet_significance_2011,
	title = {Significance of autoantibodies to soluble liver antigen ({SLA}) in autoimmune hepatitis},
	volume = {26},
	shorttitle = {Significance of autoantibodies to soluble liver antigen ({SLA}) in autoimmune hepatitis},
	abstract = {Antibody detection plays an important role in diagnosis and classification of autoimmune hepatitis. Antibodies to soluble liver antigen are considered to be a specific marker of type 1 autoimmune hepatitis. Their detection is of interest in patients who are negative for conventional markers of the disease (antinuclear antibodies and anti-smooth muscle antibodies reacting specifically against actin cables). Actually, these antibodies allow us to reclassify as type 1 autoimmune hepatitis, 15 to 20\% of hepatitis regarded as cryptogenic. The pronostic value of antibodies to soluble liver antigen has seldom been studied and is controversial. They might be used to evaluate the risk of relapse of the inflammatory process after corticosteroid therapy and to recurrence of autoimmune hepatitis after orthotopic liver transplantation.},
	number = {3},
	journal = {Immuno-analyse et biologie spécialisée},
	author = {Johanet, C. and Ballot, E.},
	month = jan,
	year = {2011},
	pages = {118--124},
}

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