@article{jonathan_p_williams_hb_2009,
	title = {Hb {Belleville} [beta 10({A7}){Ala}--{\textgreater}{Thr}] affects the determination of {Hb} {A1c} by routine cation exchange high performance liquid chromatography.},
	volume = {33},
	doi = {10.1080/03630260802625915},
	abstract = {When analyzed by routine cation exchange high performance liquid chromatography (HPLC), the Hb A1c peak of a Caucasian diabetic patient from Yorkshire, UK, appeared to be an incompletely resolved doublet. One component (5.5\%) eluted at the normal time for Hb A1c, whereas the other component (6.6\%) eluted slightly later. The HPLC trace was otherwise normal. Analysis of the diabetic patient's blood and a tryptic digest thereof by electrospray ionization mass spectrometry (ESI-MS) identified the Hb Belleville trait. To relate Hb A1c determined by HPLC to α and β chain glycation determined by ESI-MS, several normal blood samples (5–14\% Hb A1c) were analyzed by both techniques. The Hb A1c levels derived from the α and β chain glycation levels of the diabetic patient (12.9 and 12.4\%, respectively) agreed with the sum of the two peaks (12.1\%) in the HPLC trace. Similarly, Hb Belleville was detected and identified in another Caucasian, also from Yorkshire, with normal Hb A1c.},
	number = {1},
	journal = {Hemoglobin},
	author = {{Jonathan P. Williams} and {Jonathan P. Williams} and {Jonathan P. Williams} and Williams, Jonathan and Jackson, Hannah and Green, Brian N.},
	month = jul,
	year = {2009},
	doi = {10.1080/03630260802625915},
	pmid = {19205972},
	note = {MAG ID: 2018969292},
	pages = {45--50},
}

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