Itraconazole–Laponite: Kinetics and mechanism of drug release

Itraconazole–Laponite: Kinetics and mechanism of drug release. Jung, H., Kim, H., Choy, Y. B., Hwang, S., & Choy, J. Applied Clay Science, 40(1):99–107, June, 2008.

Paper doi abstract bibtex

A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH=1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.

@article{jung_itraconazolelaponite_2008,
	title = {Itraconazole–{Laponite}: {Kinetics} and mechanism of drug release},
	volume = {40},
	issn = {0169-1317},
	shorttitle = {Itraconazole–{Laponite}},
	url = {https://www.sciencedirect.com/science/article/pii/S0169131707001573},
	doi = {10.1016/j.clay.2007.09.002},
	abstract = {A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH=1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.},
	language = {en},
	number = {1},
	urldate = {2023-03-31},
	journal = {Applied Clay Science},
	author = {Jung, Hyun and Kim, Hyun-Mi and Choy, Young Bin and Hwang, Seong-Ju and Choy, Jin-Ho},
	month = jun,
	year = {2008},
	keywords = {Controlled release, Intercalation reaction, Itraconazole, Nanohybrid, Smectite clay},
	pages = {99--107},
}

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