Itraconazole–Laponite: Kinetics and mechanism of drug release. Jung, H., Kim, H., Choy, Y. B., Hwang, S., & Choy, J. Applied Clay Science, 40(1):99–107, June, 2008.
Paper doi abstract bibtex A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH=1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.
@article{jung_itraconazolelaponite_2008,
title = {Itraconazole–{Laponite}: {Kinetics} and mechanism of drug release},
volume = {40},
issn = {0169-1317},
shorttitle = {Itraconazole–{Laponite}},
url = {https://www.sciencedirect.com/science/article/pii/S0169131707001573},
doi = {10.1016/j.clay.2007.09.002},
abstract = {A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH=1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.},
language = {en},
number = {1},
urldate = {2023-03-31},
journal = {Applied Clay Science},
author = {Jung, Hyun and Kim, Hyun-Mi and Choy, Young Bin and Hwang, Seong-Ju and Choy, Jin-Ho},
month = jun,
year = {2008},
keywords = {Controlled release, Intercalation reaction, Itraconazole, Nanohybrid, Smectite clay},
pages = {99--107},
}
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