You Should Use Regression to Detect Cells. Kainz, P., Urschler, M., Schulter, S., Wohlhart, P., & Lepetit, V. Volume 9351, Navab, N., Hornegger, J., Wells, W., & Frangi, A., F., editors. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), pages 276-283. 2015.
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) [link]Website  doi  abstract   bibtex   
Automated cell detection in histopathology images is a hard problem due to the large variance of cell shape and appearance. We show that cells can be detected reliably in images by predicting, for each pixel location, a monotonous function of the distance to the center of the closest cell. Cell centers can then be identified by extracting local extremums of the predicted values. This approach results in a very simple method, which is easy to implement. We show on two challenging microscopy image datasets that our approach outperforms state-of-the-art methods in terms of accuracy, reliability, and speed. We also introduce a new dataset that we will make publicly available.
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 abstract = {Automated cell detection in histopathology images is a hard problem due to the large variance of cell shape and appearance. We show that cells can be detected reliably in images by predicting, for each pixel location, a monotonous function of the distance to the center of the closest cell. Cell centers can then be identified by extracting local extremums of the predicted values. This approach results in a very simple method, which is easy to implement. We show on two challenging microscopy image datasets that our approach outperforms state-of-the-art methods in terms of accuracy, reliability, and speed. We also introduce a new dataset that we will make publicly available.},
 bibtype = {inbook},
 author = {Kainz, Philipp and Urschler, Martin and Schulter, Samuel and Wohlhart, Paul and Lepetit, Vincent},
 editor = {Navab, N. and Hornegger, J. and Wells, W. and Frangi, A. F.},
 doi = {10.1007/978-3-319-24574-4_33},
 chapter = {You Should Use Regression to Detect Cells},
 title = {Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)}
}

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