@article{RN339,
   author = {Kamps, A. and Runhaar, J. and de Ridder, M. A. J. and de Wilde, M. and van der Lei, J. and Zhang, W. and Prieto-Alhambra, D. and Englund, M. and de Schepper, E. I. T. and Bierma-Zeinstra, S. M. A.},
   title = {Occurrence of comorbidity following osteoarthritis diagnosis: a cohort study in the Netherlands},
   journal = {Osteoarthritis Cartilage},
   volume = {31},
   number = {4},
   pages = {519-528},
   note = {1522-9653 Kamps, A Runhaar, J de Ridder, M A J de Wilde, M van der Lei, J Zhang, W Prieto-Alhambra, D Englund, M de Schepper, E I T Bierma-Zeinstra, S M A Journal Article Research Support, Non-U.S. Gov't England 2022/12/18 Osteoarthritis Cartilage. 2023 Apr;31(4):519-528. doi: 10.1016/j.joca.2022.12.003. Epub 2022 Dec 15.},
   abstract = {OBJECTIVE: To determine the risk of comorbidity following diagnosis of knee or hip osteoarthritis (OA). DESIGN: A cohort study was conducted using the Integrated Primary Care Information database, containing electronic health records of 2.5 million patients from the Netherlands. Adults at risk for OA were included. Diagnosis of knee or hip OA (=exposure) and 58 long-term comorbidities (=outcome) were defined by diagnostic codes following the International Classification of Primary Care coding system. Time between the start of follow-up and incident diagnosis of OA was defined as unexposed, and between diagnosis of OA and the end of follow-up as exposed. Age and sex adjusted hazard ratios (HRs) comparing comorbidity rates in exposed and unexposed patient time were estimated with 99.9% confidence intervals (CI). RESULTS: The study population consisted of 1,890,712 patients. For 30 of the 58 studied comorbidities, exposure to knee OA showed a HR larger than 1. Largest positive associations (HR with (99.9% CIs)) were found for obesity 2.55 (2.29-2.84) and fibromyalgia 2.06 (1.53-2.77). For two conditions a HR < 1 was found, other comorbidities showed no association with exposure to knee OA. For 26 comorbidities, exposure to hip OA showed a HR larger than 1. The largest were found for polymyalgia rheumatica 1.81 (1.41-2.32) and fibromyalgia 1.70 (1.10-2.63). All other comorbidities showed no associations with hip OA. CONCLUSION: This study showed that many comorbidities were diagnosed more often in patients with knee or hip OA. This suggests that the management of OA should consider the risk of other long-term-conditions.},
   keywords = {Adult
Humans
Cohort Studies
*Osteoarthritis, Hip/diagnosis/epidemiology
*Fibromyalgia/diagnosis/epidemiology
Netherlands/epidemiology
*Osteoarthritis, Knee/diagnosis/epidemiology
Comorbidity
Electronic health record (EHR)
Osteoarthritis
Primary care ,
ISSN = 1063-4584 ,
DOI = 10.1016/j.joca.2022.12.003},
   year = {2023},
   type = {Journal Article}
}

{"_id":"w8Joq8fhduHwyKZPq","bibbaseid":"kamps-runhaar-deridder-dewilde-vanderlei-zhang-prietoalhambra-englund-etal-occurrenceofcomorbidityfollowingosteoarthritisdiagnosisacohortstudyinthenetherlands-2023","author_short":["Kamps, A.","Runhaar, J.","de Ridder, M. A. J.","de Wilde, M.","van der Lei, J.","Zhang, W.","Prieto-Alhambra, D.","Englund, M.","de Schepper, E. I. T.","Bierma-Zeinstra, S. M. A."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Kamps"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Runhaar"],"firstnames":["J."],"suffixes":[]},{"propositions":["de"],"lastnames":["Ridder"],"firstnames":["M.","A.","J."],"suffixes":[]},{"propositions":["de"],"lastnames":["Wilde"],"firstnames":["M."],"suffixes":[]},{"propositions":["van","der"],"lastnames":["Lei"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Zhang"],"firstnames":["W."],"suffixes":[]},{"propositions":[],"lastnames":["Prieto-Alhambra"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Englund"],"firstnames":["M."],"suffixes":[]},{"propositions":["de"],"lastnames":["Schepper"],"firstnames":["E.","I.","T."],"suffixes":[]},{"propositions":[],"lastnames":["Bierma-Zeinstra"],"firstnames":["S.","M.","A."],"suffixes":[]}],"title":"Occurrence of comorbidity following osteoarthritis diagnosis: a cohort study in the Netherlands","journal":"Osteoarthritis Cartilage","volume":"31","number":"4","pages":"519-528","note":"1522-9653 Kamps, A Runhaar, J de Ridder, M A J de Wilde, M van der Lei, J Zhang, W Prieto-Alhambra, D Englund, M de Schepper, E I T Bierma-Zeinstra, S M A Journal Article Research Support, Non-U.S. Gov't England 2022/12/18 Osteoarthritis Cartilage. 2023 Apr;31(4):519-528. doi: 10.1016/j.joca.2022.12.003. Epub 2022 Dec 15.","abstract":"OBJECTIVE: To determine the risk of comorbidity following diagnosis of knee or hip osteoarthritis (OA). DESIGN: A cohort study was conducted using the Integrated Primary Care Information database, containing electronic health records of 2.5 million patients from the Netherlands. Adults at risk for OA were included. Diagnosis of knee or hip OA (=exposure) and 58 long-term comorbidities (=outcome) were defined by diagnostic codes following the International Classification of Primary Care coding system. Time between the start of follow-up and incident diagnosis of OA was defined as unexposed, and between diagnosis of OA and the end of follow-up as exposed. Age and sex adjusted hazard ratios (HRs) comparing comorbidity rates in exposed and unexposed patient time were estimated with 99.9% confidence intervals (CI). RESULTS: The study population consisted of 1,890,712 patients. For 30 of the 58 studied comorbidities, exposure to knee OA showed a HR larger than 1. Largest positive associations (HR with (99.9% CIs)) were found for obesity 2.55 (2.29-2.84) and fibromyalgia 2.06 (1.53-2.77). For two conditions a HR < 1 was found, other comorbidities showed no association with exposure to knee OA. For 26 comorbidities, exposure to hip OA showed a HR larger than 1. The largest were found for polymyalgia rheumatica 1.81 (1.41-2.32) and fibromyalgia 1.70 (1.10-2.63). All other comorbidities showed no associations with hip OA. CONCLUSION: This study showed that many comorbidities were diagnosed more often in patients with knee or hip OA. This suggests that the management of OA should consider the risk of other long-term-conditions.","keywords":"Adult Humans Cohort Studies *Osteoarthritis, Hip/diagnosis/epidemiology *Fibromyalgia/diagnosis/epidemiology Netherlands/epidemiology *Osteoarthritis, Knee/diagnosis/epidemiology Comorbidity Electronic health record (EHR) Osteoarthritis Primary care , ISSN = 1063-4584 , DOI = 10.1016/j.joca.2022.12.003","year":"2023","bibtex":"@article{RN339,\r\n author = {Kamps, A. and Runhaar, J. and de Ridder, M. A. J. and de Wilde, M. and van der Lei, J. and Zhang, W. and Prieto-Alhambra, D. and Englund, M. and de Schepper, E. I. T. and Bierma-Zeinstra, S. M. A.},\r\n title = {Occurrence of comorbidity following osteoarthritis diagnosis: a cohort study in the Netherlands},\r\n journal = {Osteoarthritis Cartilage},\r\n volume = {31},\r\n number = {4},\r\n pages = {519-528},\r\n note = {1522-9653 Kamps, A Runhaar, J de Ridder, M A J de Wilde, M van der Lei, J Zhang, W Prieto-Alhambra, D Englund, M de Schepper, E I T Bierma-Zeinstra, S M A Journal Article Research Support, Non-U.S. Gov't England 2022/12/18 Osteoarthritis Cartilage. 2023 Apr;31(4):519-528. doi: 10.1016/j.joca.2022.12.003. Epub 2022 Dec 15.},\r\n abstract = {OBJECTIVE: To determine the risk of comorbidity following diagnosis of knee or hip osteoarthritis (OA). DESIGN: A cohort study was conducted using the Integrated Primary Care Information database, containing electronic health records of 2.5 million patients from the Netherlands. Adults at risk for OA were included. Diagnosis of knee or hip OA (=exposure) and 58 long-term comorbidities (=outcome) were defined by diagnostic codes following the International Classification of Primary Care coding system. Time between the start of follow-up and incident diagnosis of OA was defined as unexposed, and between diagnosis of OA and the end of follow-up as exposed. Age and sex adjusted hazard ratios (HRs) comparing comorbidity rates in exposed and unexposed patient time were estimated with 99.9% confidence intervals (CI). RESULTS: The study population consisted of 1,890,712 patients. For 30 of the 58 studied comorbidities, exposure to knee OA showed a HR larger than 1. Largest positive associations (HR with (99.9% CIs)) were found for obesity 2.55 (2.29-2.84) and fibromyalgia 2.06 (1.53-2.77). For two conditions a HR < 1 was found, other comorbidities showed no association with exposure to knee OA. For 26 comorbidities, exposure to hip OA showed a HR larger than 1. The largest were found for polymyalgia rheumatica 1.81 (1.41-2.32) and fibromyalgia 1.70 (1.10-2.63). All other comorbidities showed no associations with hip OA. CONCLUSION: This study showed that many comorbidities were diagnosed more often in patients with knee or hip OA. This suggests that the management of OA should consider the risk of other long-term-conditions.},\r\n keywords = {Adult\r\nHumans\r\nCohort Studies\r\n*Osteoarthritis, Hip/diagnosis/epidemiology\r\n*Fibromyalgia/diagnosis/epidemiology\r\nNetherlands/epidemiology\r\n*Osteoarthritis, Knee/diagnosis/epidemiology\r\nComorbidity\r\nElectronic health record (EHR)\r\nOsteoarthritis\r\nPrimary care ,\r\nISSN = 1063-4584 ,\r\nDOI = 10.1016/j.joca.2022.12.003},\r\n year = {2023},\r\n type = {Journal Article}\r\n}\r\n\r\n","author_short":["Kamps, A.","Runhaar, J.","de Ridder, M. A. J.","de Wilde, M.","van der Lei, J.","Zhang, W.","Prieto-Alhambra, D.","Englund, M.","de Schepper, E. I. T.","Bierma-Zeinstra, S. M. A."],"key":"RN339","id":"RN339","bibbaseid":"kamps-runhaar-deridder-dewilde-vanderlei-zhang-prietoalhambra-englund-etal-occurrenceofcomorbidityfollowingosteoarthritisdiagnosisacohortstudyinthenetherlands-2023","role":"author","urls":{},"keyword":["Adult Humans Cohort Studies *Osteoarthritis","Hip/diagnosis/epidemiology *Fibromyalgia/diagnosis/epidemiology Netherlands/epidemiology *Osteoarthritis","Knee/diagnosis/epidemiology Comorbidity Electronic health record (EHR) Osteoarthritis Primary care","ISSN = 1063-4584","DOI = 10.1016/j.joca.2022.12.003"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/network/files/qwipow2DJsAxqNp83","dataSources":["PJSqX8FMpCPRdw3CQ","qLDnCcKM9omXNrRY8","TB9sD3avjy7bNxfgS","vDmJPYmHEKAT3tMNL","LPTeGao77ndnG4Tks","4uSqtC9DpXBg8PGNc","PcZMFHooKwpboi2he","jZMXEeHTfokmisJDv"],"keywords":["adult humans cohort studies *osteoarthritis","hip/diagnosis/epidemiology *fibromyalgia/diagnosis/epidemiology netherlands/epidemiology *osteoarthritis","knee/diagnosis/epidemiology comorbidity electronic health record (ehr) osteoarthritis primary care","issn = 1063-4584","doi = 10.1016/j.joca.2022.12.003"],"search_terms":["occurrence","comorbidity","following","osteoarthritis","diagnosis","cohort","study","netherlands","kamps","runhaar","de ridder","de wilde","van der lei","zhang","prieto-alhambra","englund","de schepper","bierma-zeinstra"],"title":"Occurrence of comorbidity following osteoarthritis diagnosis: a cohort study in the Netherlands","year":2023}