@article{kartoun2019factors,
  title={Factors associated with clinical inertia in type 2 diabetes mellitus patients treated with metformin monotherapy},
  author={Kartoun, Uri and Iglay, Kristy and Shankar, R Ravi and Beam, Andrew and Radican, Larry and Chatterjee, Arnaub and Pai, Jennifer K and Shaw, Stanley},
  journal={Current medical research and opinion},
  number={just-accepted},
  pages={1--1},
  year={2019},
  abstract={AIMS: To assess demographic and clinical characteristics associated with clinical inertia in a real-world cohort of type 2 diabetes mellitus patients not at hemoglobin A1c goal (<7%) on metformin monotherapy.

METHODS: Adult (≥18 years) type 2 diabetes mellitus patients who received care at Massachusetts General Hospital/Brigham and Women’s Hospital and received a new metformin prescription between 1992 and 2010 were included in the analysis. Clinical inertia was defined as two consecutive hemoglobin A1c measures ≥7% ≥3 months apart while remaining on metformin monotherapy (i.e., without add-on therapy). The association between clinical inertia and demographic and clinical characteristics was examined via logistic regression.

RESULTS: Of 2,848 eligible patients, 43% did not achieve hemoglobin A1c goal of <7% 3 months after metformin monotherapy initiation. A subgroup of 1,533 patients was included in the clinical inertia analysis, of which 36% experienced clinical inertia. Asian race was associated with an increased likelihood of clinical inertia (Odds ratio, 2.43; 95% Confidence interval, 1.48–3.96), while congestive heart failure had a decreased likelihood (Odds ratio, 0.58; 95% Confidence interval, 0.32–0.98). Chronic kidney disease and cardiovascular/cerebrovascular disease had weaker associations but were directionally similar to congestive heart failure.

CONCLUSIONS: Asian patients were at an increased risk of clinical inertia, whereas patients with comorbidities appeared to have their treatment more appropriately intensified. A better understanding of these factors may inform efforts to decrease likelihood for clinical inertia.},
  url_Paper={https://www.dropbox.com/s/n67gvoinw7jenwj/kartoun_clinicalinertia_2019.textClipping?dl=1},
  publisher={Taylor \& Francis},
    keywords={Healthcare}
}

{"_id":"X6rFSs25okfodzJLA","bibbaseid":"kartoun-iglay-shankar-beam-radican-chatterjee-pai-shaw-factorsassociatedwithclinicalinertiaintype2diabetesmellituspatientstreatedwithmetforminmonotherapy-2019","authorIDs":[],"author_short":["Kartoun, U.","Iglay, K.","Shankar, R R.","Beam, A.","Radican, L.","Chatterjee, A.","Pai, J. K","Shaw, S."],"bibdata":{"bibtype":"article","type":"article","title":"Factors associated with clinical inertia in type 2 diabetes mellitus patients treated with metformin monotherapy","author":[{"propositions":[],"lastnames":["Kartoun"],"firstnames":["Uri"],"suffixes":[]},{"propositions":[],"lastnames":["Iglay"],"firstnames":["Kristy"],"suffixes":[]},{"propositions":[],"lastnames":["Shankar"],"firstnames":["R","Ravi"],"suffixes":[]},{"propositions":[],"lastnames":["Beam"],"firstnames":["Andrew"],"suffixes":[]},{"propositions":[],"lastnames":["Radican"],"firstnames":["Larry"],"suffixes":[]},{"propositions":[],"lastnames":["Chatterjee"],"firstnames":["Arnaub"],"suffixes":[]},{"propositions":[],"lastnames":["Pai"],"firstnames":["Jennifer","K"],"suffixes":[]},{"propositions":[],"lastnames":["Shaw"],"firstnames":["Stanley"],"suffixes":[]}],"journal":"Current medical research and opinion","number":"just-accepted","pages":"1–1","year":"2019","abstract":"AIMS: To assess demographic and clinical characteristics associated with clinical inertia in a real-world cohort of type 2 diabetes mellitus patients not at hemoglobin A1c goal (<7%) on metformin monotherapy. METHODS: Adult (≥18 years) type 2 diabetes mellitus patients who received care at Massachusetts General Hospital/Brigham and Women’s Hospital and received a new metformin prescription between 1992 and 2010 were included in the analysis. Clinical inertia was defined as two consecutive hemoglobin A1c measures ≥7% ≥3 months apart while remaining on metformin monotherapy (i.e., without add-on therapy). The association between clinical inertia and demographic and clinical characteristics was examined via logistic regression. RESULTS: Of 2,848 eligible patients, 43% did not achieve hemoglobin A1c goal of <7% 3 months after metformin monotherapy initiation. A subgroup of 1,533 patients was included in the clinical inertia analysis, of which 36% experienced clinical inertia. Asian race was associated with an increased likelihood of clinical inertia (Odds ratio, 2.43; 95% Confidence interval, 1.48–3.96), while congestive heart failure had a decreased likelihood (Odds ratio, 0.58; 95% Confidence interval, 0.32–0.98). Chronic kidney disease and cardiovascular/cerebrovascular disease had weaker associations but were directionally similar to congestive heart failure. CONCLUSIONS: Asian patients were at an increased risk of clinical inertia, whereas patients with comorbidities appeared to have their treatment more appropriately intensified. A better understanding of these factors may inform efforts to decrease likelihood for clinical inertia.","url_paper":"https://www.dropbox.com/s/n67gvoinw7jenwj/kartoun_clinicalinertia_2019.textClipping?dl=1","publisher":"Taylor & Francis","keywords":"Healthcare","bibtex":"@article{kartoun2019factors,\n title={Factors associated with clinical inertia in type 2 diabetes mellitus patients treated with metformin monotherapy},\n author={Kartoun, Uri and Iglay, Kristy and Shankar, R Ravi and Beam, Andrew and Radican, Larry and Chatterjee, Arnaub and Pai, Jennifer K and Shaw, Stanley},\n journal={Current medical research and opinion},\n number={just-accepted},\n pages={1--1},\n year={2019},\n abstract={AIMS: To assess demographic and clinical characteristics associated with clinical inertia in a real-world cohort of type 2 diabetes mellitus patients not at hemoglobin A1c goal (<7%) on metformin monotherapy.\n\nMETHODS: Adult (≥18 years) type 2 diabetes mellitus patients who received care at Massachusetts General Hospital/Brigham and Women’s Hospital and received a new metformin prescription between 1992 and 2010 were included in the analysis. Clinical inertia was defined as two consecutive hemoglobin A1c measures ≥7% ≥3 months apart while remaining on metformin monotherapy (i.e., without add-on therapy). The association between clinical inertia and demographic and clinical characteristics was examined via logistic regression.\n\nRESULTS: Of 2,848 eligible patients, 43% did not achieve hemoglobin A1c goal of <7% 3 months after metformin monotherapy initiation. A subgroup of 1,533 patients was included in the clinical inertia analysis, of which 36% experienced clinical inertia. Asian race was associated with an increased likelihood of clinical inertia (Odds ratio, 2.43; 95% Confidence interval, 1.48–3.96), while congestive heart failure had a decreased likelihood (Odds ratio, 0.58; 95% Confidence interval, 0.32–0.98). Chronic kidney disease and cardiovascular/cerebrovascular disease had weaker associations but were directionally similar to congestive heart failure.\n\nCONCLUSIONS: Asian patients were at an increased risk of clinical inertia, whereas patients with comorbidities appeared to have their treatment more appropriately intensified. A better understanding of these factors may inform efforts to decrease likelihood for clinical inertia.},\n url_Paper={https://www.dropbox.com/s/n67gvoinw7jenwj/kartoun_clinicalinertia_2019.textClipping?dl=1},\n publisher={Taylor \\& Francis},\n keywords={Healthcare}\n}\n\n\n","author_short":["Kartoun, U.","Iglay, K.","Shankar, R R.","Beam, A.","Radican, L.","Chatterjee, A.","Pai, J. K","Shaw, S."],"key":"kartoun2019factors","id":"kartoun2019factors","bibbaseid":"kartoun-iglay-shankar-beam-radican-chatterjee-pai-shaw-factorsassociatedwithclinicalinertiaintype2diabetesmellituspatientstreatedwithmetforminmonotherapy-2019","role":"author","urls":{" paper":"https://www.dropbox.com/s/n67gvoinw7jenwj/kartoun_clinicalinertia_2019.textClipping?dl=1"},"keyword":["Healthcare"],"metadata":{"authorlinks":{}},"downloads":2,"html":""},"bibtype":"article","biburl":"https://www.dropbox.com/s/0k6pa735xx3gr9i/citations.txt?dl=1","creationDate":"2019-08-13T12:58:15.190Z","downloads":2,"keywords":["healthcare"],"search_terms":["factors","associated","clinical","inertia","type","diabetes","mellitus","patients","treated","metformin","monotherapy","kartoun","iglay","shankar","beam","radican","chatterjee","pai","shaw"],"title":"Factors associated with clinical inertia in type 2 diabetes mellitus patients treated with metformin monotherapy","year":2019,"dataSources":["2LQLmS62hSLmYBK2a","R7XXNLtmcExJiuMoA"]}