Assessment of reperfusion in myocardial infarction by body surface electrocardiographic mapping. Kilpatrick, D., Bell, A., & Briggs, C. j-JE, 26(4):279--89, 1993.
bibtex   
@Article{RSM:Kil93,
  author =       "D. Kilpatrick and A.J. Bell and C. Briggs",
  title =        "Assessment of reperfusion in myocardial infarction by
                 body surface electrocardiographic mapping.",
  journal =      j-JE,
  year =         "1993",
  volume =       "26",
  number =       "4",
  pages =        "279--89",
  robnote =      "To determine the efficacy of body surface potential
                 mapping to detect and quantify reperfusion in acute
                 infarction, 66 patients were studied by repeated body
                 surface potential mapping before and after
                 administration of the thrombolytic agent. The QRS and
                 ST-segment were analyzed and compared to the arterial
                 patency as assessed by arteriography within 10 days.
                 The infarct-related vessel was patent in 50 patients
                 and occluded in the remaining 16. In 6 of the 15
                 patients in whom thrombolytic therapy was started
                 within 2 hours of the onset of chest pain the
                 ST-segment changed from that of an acute infarction
                 pattern to that of a normal pattern, and the QRS
                 pattern either remained normal or recovered prior to
                 discharge. In two additional patients the QRS pattern
                 returned to normal prior to discharge from the
                 hospital. In the 51 patients with later thrombolytic
                 therapy (> or = 2 hours) the degree of ST elevation and
                 depression decreased more than either the control
                 infarction group (36 inferior and 73 anterior patients)
                 or the group in whom reperfusion attempts were
                 unsuccessful, but the pattern of the map remained that
                 of an infarction. The QRS maps showed that in the first
                 48 hours recovery of potential was insufficient to
                 distinguish those with successful thrombolysis. Early
                 reperfusion could be detected by body surface potential
                 mapping and the eventual damage predicted from the
                 degree of change in the QRS map. Later reperfusion
                 could be surmised but not quantified.",
}

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