An ε-caprolactone-derived 2-oxazoline inimer for the synthesis of graft copolymers. Kim, J., Waldron, C., Cattoz, B., & Becer, C. R. POLYMER CHEMISTRY, 11(42):6847–6852, November, 2020. Infineum UK Ltd
doi  abstract   bibtex   
An inimer approach is presented here for the formation of bottlebrush copolymers consisting of a poly(2-oxazoline) backbone and acrylate branches. A hydroxyl group containing 2-oxazoline (2-n-pentanol-2-oxazoline) was synthesized from epsilon-caprolactone, which is a sustainable starting material. 2-n-Pentanol-2-oxazoline was then further functionalized with a bromoisobutyrate group, which was used to initiate a Cu(0)-mediated reversible-deactivation radical polymerisation (RDRP) of acrylates. This compound is termed an "inimer" because it contains both a monomer (2-oxazoline) and an initiator (the RDRP initiator in this study). Herein, we report the use of an inimer to form 2-oxazoline-based polymer backbones through cationic ring opening polymerisation, and further polymerisation via the Cu(0)-mediated RDRP of acrylates was achieved by initiating from the RDRP-initiator sites embedded within the poly(2-oxazoline) backbone. Furthermore, statistical copolymers of 2-ethyl 2-oxazoline and the inimer were also formed leading to statistically distributed radical initiating sites, which were then used to form graft copolymers of varying densities.
@article{kim_-caprolactone-derived_2020,
	title = {An ε-caprolactone-derived 2-oxazoline inimer for the synthesis of graft copolymers},
	volume = {11},
	issn = {1759-9954},
	doi = {10.1039/d0py01092h},
	abstract = {An inimer approach is presented here for the formation of bottlebrush copolymers consisting of a poly(2-oxazoline) backbone and acrylate branches. A hydroxyl group containing 2-oxazoline (2-n-pentanol-2-oxazoline) was synthesized from epsilon-caprolactone, which is a sustainable starting material. 2-n-Pentanol-2-oxazoline was then further functionalized with a bromoisobutyrate group, which was used to initiate a Cu(0)-mediated reversible-deactivation radical polymerisation (RDRP) of acrylates. This compound is termed an "inimer" because it contains both a monomer (2-oxazoline) and an initiator (the RDRP initiator in this study). Herein, we report the use of an inimer to form 2-oxazoline-based polymer backbones through cationic ring opening polymerisation, and further polymerisation via the Cu(0)-mediated RDRP of acrylates was achieved by initiating from the RDRP-initiator sites embedded within the poly(2-oxazoline) backbone. Furthermore, statistical copolymers of 2-ethyl 2-oxazoline and the inimer were also formed leading to statistically distributed radical initiating sites, which were then used to form graft copolymers of varying densities.},
	number = {42},
	urldate = {2020-11-17},
	journal = {POLYMER CHEMISTRY},
	author = {Kim, Jungyeon and Waldron, Christopher and Cattoz, Beatrice and Becer, C. Remzi},
	month = nov,
	year = {2020},
	note = {Infineum UK Ltd},
	pages = {6847--6852},
}

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