Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies. Kleo, K., Jovanovic, V. M., Arndold, A., Lehmann, A., Lammert, H., Berg, E., Harloff, H., Treese, C., Hummel, M., & Daum, S. Journal of Cancer Research and Clinical Oncology, March, 2022. Paper doi abstract bibtex 6 downloads Perioperative chemo-(radio-) therapy is the accepted standard in European patients with locally advanced adenocarcinoma of the esophagogastric junction or stomach (AEG/AS). However, 30–85% of patients do not respond to this treatment. The aim of our study was the identification of predictive biomarkers in pre-therapeutic endoscopic tumor biopsies from patients with histopathologic response (Becker-1) versus non-response (Becker-2/3) to preoperative chemotherapy.
@article{kleo_response_2022,
title = {Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies},
issn = {1432-1335},
url = {https://doi.org/10.1007/s00432-022-03944-z},
doi = {10.1007/s00432-022-03944-z},
abstract = {Perioperative chemo-(radio-) therapy is the accepted standard in European patients with locally advanced adenocarcinoma of the esophagogastric junction or stomach (AEG/AS). However, 30–85\% of patients do not respond to this treatment. The aim of our study was the identification of predictive biomarkers in pre-therapeutic endoscopic tumor biopsies from patients with histopathologic response (Becker-1) versus non-response (Becker-2/3) to preoperative chemotherapy.},
language = {en},
urldate = {2022-03-15},
journal = {Journal of Cancer Research and Clinical Oncology},
author = {Kleo, Karsten and Jovanovic, Vladimir M. and Arndold, Alexander and Lehmann, Annika and Lammert, Hedwig and Berg, Erika and Harloff, Hannah and Treese, Christoph and Hummel, Michael and Daum, Severin},
month = mar,
year = {2022},
keywords = {SOPHiA DDM},
}
Downloads: 6
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