Predictive value of T-wave alternans for arrhythmic events in patients with congestive heart failure. Klingenheben, T., Zabel, M., D'Agostino, R., B., Cohen, R., J., & Hohnloser, S., H. Lancet, 356(9230):651-2, 2000. Paper Website abstract bibtex Measurement of microvolt level T-wave alternans in the surface electrocardiogram is a novel way to assess the risk of ventricular arrhythmias. Seven tests of arrhythmic risk, including T-wave alternans, were undertaken in 107 consecutive patients with congestive heart failure and no history of sustained ventricular arrhythmias; the patients were followed up for arrhythmic events during the next 18 months. Of the patients with events, 11 had positive and two indeterminate T-wave alternans results; there were no arrhythmic events among patients with negative T-wave alternans results. Of the seven tests, only T-wave alternans was a significant (p=0.0036) and independent predictor of arrhythmic events.
@article{
title = {Predictive value of T-wave alternans for arrhythmic events in patients with congestive heart failure.},
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year = {2000},
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keywords = {Arrhythmias,Cardiac,Cardiac: diagnosis,Cardiac: etiology,Cardiac: physiopathology,Electrocardiography,Female,Follow-Up Studies,Heart Failure,Heart Failure: complications,Heart Failure: physiopathology,Humans,Male,Middle Aged,Multivariate Analysis,Predictive Value of Tests,Proportional Hazards Models,Risk Assessment,Survival Rate},
pages = {651-2},
volume = {356},
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abstract = {Measurement of microvolt level T-wave alternans in the surface electrocardiogram is a novel way to assess the risk of ventricular arrhythmias. Seven tests of arrhythmic risk, including T-wave alternans, were undertaken in 107 consecutive patients with congestive heart failure and no history of sustained ventricular arrhythmias; the patients were followed up for arrhythmic events during the next 18 months. Of the patients with events, 11 had positive and two indeterminate T-wave alternans results; there were no arrhythmic events among patients with negative T-wave alternans results. Of the seven tests, only T-wave alternans was a significant (p=0.0036) and independent predictor of arrhythmic events.},
bibtype = {article},
author = {Klingenheben, T and Zabel, M and D'Agostino, R B and Cohen, Richard J and Hohnloser, S H},
journal = {Lancet},
number = {9230}
}
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