@article{Koch2018,
abstract = {With an estimated incidence of 490000 cases in 2016, multidrug resistant tuberculosis (TB), against which key first-line anti-tuberculars are less efficacious, presents major challenges for global health. Poor treatment outcomes coupled with a yawning treatment gap between those in need of second-line therapy and those who receive it, underscore the urgent need for new approaches to tackle the scourge of drug-resistant TB. Against this background, significant progress has been made in understanding the complex biology of TB drug resistance and disease pathogenesis, and in establishing a pipeline for delivering new drugs and drug combinations. In this review, we highlight the challenges of drug-resistant TB and the ways in which new advances could be harnessed to improve treatment outcomes.},
author = {Koch, Anastasia Sideris and Cox, Helen and Mizrahi, Valerie},
doi = {10.1016/J.COPH.2018.05.013},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Koch, Cox, Mizrahi - 2018 - Drug-resistant tuberculosis challenges and opportunities for diagnosis and treatment.pdf:pdf},
journal = {Current Opinion in Pharmacology},
keywords = {fund{\_}not{\_}ack,review},
mendeley-tags = {fund{\_}not{\_}ack,review},
month = {oct},
pages = {7--15},
pmid = {29885623},
publisher = {Elsevier},
title = {{Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment}},
url = {https://www.sciencedirect.com/science/article/pii/S1471489217301571},
volume = {42},
year = {2018}
}

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