Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways. Kohlfaerber, T., Pieper, M., Pieper, M., Münter, M., Holzhausen, C., Ahrens, M., Ahrens, M., Idel, C., Bruchhage, K., Leichtle, A., König, P., König, P., Hüttmann, G., Hüttmann, G., Hüttmann, G., Hüttmann, G., Schulz-Hildebrandt, H., Schulz-Hildebrandt, H., & Schulz-Hildebrandt, H. Biomedical Optics Express, 13(6):3211–3223, June, 2022. Publisher: Optica Publishing Group![Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex In the imaging of airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using fast sequences of microscopic resolution OCT (mOCT) images, OCT can use small signal fluctuations to overcome lack in contrast and speckle noise. In this way, OCT visualizes airway morphology on a cellular level and allows the tracking of the dynamic behavior of immune cells, as well as mucus transport and secretion. Here, we demonstrate that mOCT, by using temporal tissue fluctuation as contrast (dynamic mOCT), provides the possibility to study physiological and pathological tissue processes in vivo.
@article{kohlfaerber_dynamic_2022,
title = {Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways},
volume = {13},
copyright = {\&\#169; 2022 Optica Publishing Group},
issn = {2156-7085},
url = {https://opg.optica.org/boe/abstract.cfm?uri=boe-13-6-3211},
doi = {10.1364/BOE.456104},
abstract = {In the imaging of airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using fast sequences of microscopic resolution OCT (mOCT) images, OCT can use small signal fluctuations to overcome lack in contrast and speckle noise. In this way, OCT visualizes airway morphology on a cellular level and allows the tracking of the dynamic behavior of immune cells, as well as mucus transport and secretion. Here, we demonstrate that mOCT, by using temporal tissue fluctuation as contrast (dynamic mOCT), provides the possibility to study physiological and pathological tissue processes in\&\#x2009;vivo.},
language = {EN},
number = {6},
urldate = {2022-11-21},
journal = {Biomedical Optics Express},
author = {Kohlfaerber, Tabea and Pieper, Mario and Pieper, Mario and Münter, Michael and Holzhausen, Cornelia and Ahrens, Martin and Ahrens, Martin and Idel, Christian and Bruchhage, Karl-Ludwig and Leichtle, Anke and König, Peter and König, Peter and Hüttmann, Gereon and Hüttmann, Gereon and Hüttmann, Gereon and Hüttmann, Gereon and Schulz-Hildebrandt, Hinnerk and Schulz-Hildebrandt, Hinnerk and Schulz-Hildebrandt, Hinnerk},
month = jun,
year = {2022},
note = {Publisher: Optica Publishing Group},
pages = {3211--3223},
}
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