Development of the nervous system of Aplysia californica. Kriegstein, A R Proc Natl Acad Sci U S A, 74(1):375–378, January, 1977.
abstract   bibtex   
The ability to grow the marine molluse Aplysia under laboratory conditions allows a detailed study of the formation of the nervous system and of the development of specific identified cells. I have found that the ganglia develop in a specific temporal order. Cerebral and pedal ganglia develop at hatching, the abdominal, pleural, and osphradial ganglia 3 weeks after hatching, and the buccal ganglia at 4 weeks. The origin of the abdominal ganglion is complex; its anlage forms at 3 weeks from three larval ganglia that fuse to form the abdominal ganglion. Individual cells cannot be distinguished from one another by their location within the ganglion or by their appearance alone until metamorphosis at 5 weeks. After metamorphosis, the identified neuron, R2, suddenly becomes recognizable because of a significant increase in its size.
@ARTICLE{Kriegstein1977-vv,
  title    = "Development of the nervous system of Aplysia californica",
  author   = "Kriegstein, A R",
  abstract = "The ability to grow the marine molluse Aplysia under laboratory
              conditions allows a detailed study of the formation of the
              nervous system and of the development of specific identified
              cells. I have found that the ganglia develop in a specific
              temporal order. Cerebral and pedal ganglia develop at hatching,
              the abdominal, pleural, and osphradial ganglia 3 weeks after
              hatching, and the buccal ganglia at 4 weeks. The origin of the
              abdominal ganglion is complex; its anlage forms at 3 weeks from
              three larval ganglia that fuse to form the abdominal ganglion.
              Individual cells cannot be distinguished from one another by
              their location within the ganglion or by their appearance alone
              until metamorphosis at 5 weeks. After metamorphosis, the
              identified neuron, R2, suddenly becomes recognizable because of a
              significant increase in its size.",
  journal  = "Proc Natl Acad Sci U S A",
  volume   =  74,
  number   =  1,
  pages    = "375--378",
  month    =  jan,
  year     =  1977,
  language = "en"
}

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