@ARTICLE{Kriegstein2003-qp,
  title    = "Radial glia diversity: a matter of cell fate",
  author   = "Kriegstein, Arnold R and G{\"o}tz, Magdalena",
  abstract = "Early in development of the central nervous system, radial glial
              cells arise from the neuroepithelial cells lining the ventricles
              around the time that neurons begin to appear. The transition of
              neuroepithelial cells to radial glia is accompanied by a series
              of structural and functional changes, including the appearance of
              ``glial'' features, as well as the appearance of new signaling
              molecules and junctional proteins. However, not all radial glia
              are alike. Radial glial lineages appear to be heterogeneous both
              within and across different brain regions. Subtypes of neurogenic
              radial glia within the cortex, for example, may have restricted
              potential in terms of the cell types they are able to generate.
              Radial glia located in different brain regions also differ in
              their expression of growth factors, a diverse number of
              transcription factors, and the cell types they generate,
              suggesting that they are involved in regionalization of the
              developing nervous system in several aspects. These findings
              highlight the important but complex role of radial glia as
              participants in key steps of brain development.",
  journal  = "Glia",
  volume   =  43,
  number   =  1,
  pages    = "37--43",
  month    =  jul,
  year     =  2003,
  address  = "United States",
  language = "en"
}

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