@ARTICLE{Kriegstein2001-qw,
  title    = "{GABA} may act as a self-limiting trophic factor at developing
              synapses",
  author   = "Kriegstein, A R and Owens, D F",
  abstract = "Early in development, synapses with glycine or gamma-aminobutyric
              acid (GABA)-gated chloride channels exhibit the ability to
              depolarize postsynaptic cells. As the synapses mature and the
              gradient of chloride ions across the cell membrane is altered,
              these neurotransmitters signal an inhibitory response,
              hyperpolarizing the membrane and decreasing neuronal
              excitability. Kriegstein and Owens discuss how GABA-stimulated
              up-regulation of the expression of the potassium chloride
              cotransporter KCC2 may be the mechanism underlying this synaptic
              switch.",
  journal  = "Sci STKE",
  volume   =  2001,
  number   =  95,
  pages    = "e1",
  month    =  aug,
  year     =  2001,
  address  = "United States",
  language = "en"
}

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