Commentary: the prospect of cell-based therapy for epilepsy. Kriegstein, A. R & Pitkänen, A. Neurotherapeutics, 6(2):295–299, April, 2009.
abstract   bibtex   
About 30% of patient with epilepsy do not respond to available antiepileptic drugs. In addition to seizure suppression, novel approaches are needed to prevent or alleviate epileptogenic process after various types of brain injuries. The use of cell transplants as factories to produce endogeneous anticonvulsants or as bricks to repair abnormal ictogenic and epileptogenic neuronal circuits has generated hope that cell-based therapies could become a novel therapeutic category in the treatment arsenal of epilepsy. Herein we summarize the current status and future perspectives of cell-based therapies in the treatment of epilepsy.
@ARTICLE{Kriegstein2009-fa,
  title    = "Commentary: the prospect of cell-based therapy for epilepsy",
  author   = "Kriegstein, Arnold R and Pitk{\"a}nen, Asla",
  abstract = "About 30\% of patient with epilepsy do not respond to available
              antiepileptic drugs. In addition to seizure suppression, novel
              approaches are needed to prevent or alleviate epileptogenic
              process after various types of brain injuries. The use of cell
              transplants as factories to produce endogeneous anticonvulsants
              or as bricks to repair abnormal ictogenic and epileptogenic
              neuronal circuits has generated hope that cell-based therapies
              could become a novel therapeutic category in the treatment
              arsenal of epilepsy. Herein we summarize the current status and
              future perspectives of cell-based therapies in the treatment of
              epilepsy.",
  journal  = "Neurotherapeutics",
  volume   =  6,
  number   =  2,
  pages    = "295--299",
  month    =  apr,
  year     =  2009,
  language = "en"
}

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