@ARTICLE{Kriegstein1983-pi,
  title    = "Cholinergic enhancement of penicillin-induced epileptiform
              discharges in pyramidal neurons of the guinea pig hippocampus",
  author   = "Kriegstein, A R and Suppes, T and Prince, D A",
  abstract = "Acetylcholine (1-20 mM) was applied to guinea pig hippocampal
              slices bathed in normal and penicillin-containing media.
              Recordings in the CA 1 pyramidal cell layer in the presence of
              penicillin showed that acetylcholine caused a prolonged
              enhancement of the extracellular field potential. Intracellular
              recordings documented an increase in duration of cell bursting, a
              decrease in burst afterhyperpolarization, and a membrane
              depolarization lasting 1-5 min. These results suggest that the
              actions of acetylcholine to increase membrane excitability
              interact with penicillin-induced disinhibition to enhance
              hippocampal epileptogenesis.",
  journal  = "Brain Res",
  volume   =  266,
  number   =  1,
  pages    = "137--142",
  month    =  apr,
  year     =  1983,
  address  = "Netherlands",
  language = "en"
}

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