Clinical Decision Support for Skin Tumor Treatment: A Case-Based Reasoning Approach. Kuhn, M., Warnecke, Y., Preciado-Marquez, D., Grüger, J., Bley, L. I., Storck, M., Weishaupt, C., Bergmann, R., & Braun, S. A. In Bichindaritz, I. & López, B., editors, Case-Based Reasoning Research and Development, pages 407–422, Cham, 2025. Springer Nature Switzerland.
abstract   bibtex   
Cancer treatment planning is a complex and individualized process due to the variability of patient-specific factors, tumor characteristics, and evolving medical standards. Predicting the next step in diagnosis or therapy remains a significant challenge, due to the high variability and limited availability of structured medical data. Clinical Decision Support Systems (CDSS) offer a promising solution, with Case-Based Reasoning (CBR) standing out for its ability to provide interpretable and transparent recommendations. Unlike black-box machine learning models, CBR leverages past cases to generate predictions by analogy, aligning with the way clinicians naturally reason. In this work, we propose a CBR-based CDSS for skin cancer treatment that integrates medical taxonomies and patient-specific clinical features to predict the next treatment step. By focusing on both technical performance and real-world application in a medical setting, this study provides insights for the deployment of CBR-based systems in medical practice.
@InProceedings{CBR_CDSS_2025,
author="Kuhn, Martin
and Warnecke, Yannik
and Preciado-Marquez, Daniel
and Gr{\"u}ger, Joscha
and Bley, Laura Isabell
and Storck, Michael
and Weishaupt, Carsten
and Bergmann, Ralph
and Braun, Stephan Alexander",
editor="Bichindaritz, Isabelle
and L{\'o}pez, Beatriz",
title="Clinical Decision Support for Skin Tumor Treatment: A Case-Based Reasoning Approach",
booktitle="Case-Based Reasoning Research and Development",
year="2025",
publisher="Springer Nature Switzerland",
address="Cham",
pages="407--422",
abstract="Cancer treatment planning is a complex and individualized process due to the variability of patient-specific factors, tumor characteristics, and evolving medical standards. Predicting the next step in diagnosis or therapy remains a significant challenge, due to the high variability and limited availability of structured medical data. Clinical Decision Support Systems (CDSS) offer a promising solution, with Case-Based Reasoning (CBR) standing out for its ability to provide interpretable and transparent recommendations. Unlike black-box machine learning models, CBR leverages past cases to generate predictions by analogy, aligning with the way clinicians naturally reason. In this work, we propose a CBR-based CDSS for skin cancer treatment that integrates medical taxonomies and patient-specific clinical features to predict the next treatment step. By focusing on both technical performance and real-world application in a medical setting, this study provides insights for the deployment of CBR-based systems in medical practice.",
isbn="978-3-031-96559-3"
}

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