Characteristics of hospital-associated influenza in a tertiary care adult Hospital in Singapore, 2011-2015. Kyaw, W. M., Aung, A. H., Loh, J., Ho, H., & Chow, A. Annals of the Academy of Medicine Singapore, 45(9 Supplement 1):S82, 2016. ![Characteristics of hospital-associated influenza in a tertiary care adult Hospital in Singapore, 2011-2015 [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex Background & Hypothesis: Hospital-associated influenza is known to contribute to morbidity and mortality among hospitalised patients. Method(s): We conducted a retrospective review of all patients with laboratory-confirmed influenza from January 2011 to December 2015, and compared community-associated (CA, laboratory-confirmed influenza \textless=3 days after admission) with hospital-associated (HA, laboratory-confirmed \textgreater3 days after admission) influenza. Result(s): There were 5729 patient-admissions (69% aged \textgreater=65 years, 51% female and 3.3% of HA) with influenza A/H3 (59%), A/H1N1-2009 (16%), B (16%) and A/subtype-undetermined (9%) during the study period. HA cases were more likely to be of older age (P = 0.037), or have chronic medical conditions such as cerebrovascular disease (P \textless0.001), congestive heart failure (P = 0.002), renal disease (P = 0.045), any malignancy (P \textless0.001) or HIV infection (P \textless0.001). The median length of stay after influenza diagnosis for HA influenza (8 days) was greater than that for CA influenza (4 days) (P \textless0.001). A larger proportion of HA cases (18%) than CA (7%) cases needed ICU care or died (P \textless0.001). On multivariate analysis, factors independently associated with HA influenza were comorbidities of cerebrovascular disease (AOR 2.85, 95% CI 1.78-4.56), congestive heart failure (AOR 1.57, 95% CI 1.05-2.35), any malignancy (AOR 2.85, 95% CI 1.70-4.79), and HIV infection (AOR 13.32, 95% CI 4.08-43.46). In contrast, chronic pulmonary disease (AOR 0.56, 95% CI 0.36- 0.86) and influenza B (AOR 0.58, 95% CI 0.39-0.88) were less common in HA influenza, after adjusting for age and gender. Discussion & Conclusion(s): Annual influenza vaccination should be actively promoted not only to patients with chronic medical conditions but also to healthcare workers attending to patients, to prevent HA influenza.
@article{kyaw_characteristics_2016,
title = {Characteristics of hospital-associated influenza in a tertiary care adult {Hospital} in {Singapore}, 2011-2015},
volume = {45},
issn = {0304-4602},
url = {http://www.annals.edu.sg/pdf/45VolNo9Sep2016/SHBC2016.pdf http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed17&NEWS=N&AN=612898364},
abstract = {Background \& Hypothesis: Hospital-associated influenza is known to contribute to morbidity and mortality among hospitalised patients. Method(s): We conducted a retrospective review of all patients with laboratory-confirmed influenza from January 2011 to December 2015, and compared community-associated (CA, laboratory-confirmed influenza {\textless}=3 days after admission) with hospital-associated (HA, laboratory-confirmed {\textgreater}3 days after admission) influenza. Result(s): There were 5729 patient-admissions (69\% aged {\textgreater}=65 years, 51\% female and 3.3\% of HA) with influenza A/H3 (59\%), A/H1N1-2009 (16\%), B (16\%) and A/subtype-undetermined (9\%) during the study period. HA cases were more likely to be of older age (P = 0.037), or have chronic medical conditions such as cerebrovascular disease (P {\textless}0.001), congestive heart failure (P = 0.002), renal disease (P = 0.045), any malignancy (P {\textless}0.001) or HIV infection (P {\textless}0.001). The median length of stay after influenza diagnosis for HA influenza (8 days) was greater than that for CA influenza (4 days) (P {\textless}0.001). A larger proportion of HA cases (18\%) than CA (7\%) cases needed ICU care or died (P {\textless}0.001). On multivariate analysis, factors independently associated with HA influenza were comorbidities of cerebrovascular disease (AOR 2.85, 95\% CI 1.78-4.56), congestive heart failure (AOR 1.57, 95\% CI 1.05-2.35), any malignancy (AOR 2.85, 95\% CI 1.70-4.79), and HIV infection (AOR 13.32, 95\% CI 4.08-43.46). In contrast, chronic pulmonary disease (AOR 0.56, 95\% CI 0.36- 0.86) and influenza B (AOR 0.58, 95\% CI 0.39-0.88) were less common in HA influenza, after adjusting for age and gender. Discussion \& Conclusion(s): Annual influenza vaccination should be actively promoted not only to patients with chronic medical conditions but also to healthcare workers attending to patients, to prevent HA influenza.},
language = {English},
number = {9 Supplement 1},
journal = {Annals of the Academy of Medicine Singapore},
author = {Kyaw, W. M. and Aung, A. H. and Loh, J. and Ho, H. and Chow, A.},
year = {2016},
keywords = {*Influenza A virus (H1N1), *Singapore, *doctor patient relation, *nonhuman, *tertiary health care, Human immunodeficiency virus infection, adult, aged, cerebrovascular disease, chronic lung disease, comorbidity, congestive heart failure, controlled study, diagnosis, female, gender, health care personnel, hospital admission, human, influenza B, influenza vaccination, kidney disease, length of stay, major clinical study, male, malignant neoplastic disease, multivariate analysis, prevention, retrospective study},
pages = {S82},
}
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{"_id":"LCobZZxBA7F7fo3j5","bibbaseid":"kyaw-aung-loh-ho-chow-characteristicsofhospitalassociatedinfluenzainatertiarycareadulthospitalinsingapore20112015-2016","authorIDs":[],"author_short":["Kyaw, W. M.","Aung, A. H.","Loh, J.","Ho, H.","Chow, A."],"bibdata":{"bibtype":"article","type":"article","title":"Characteristics of hospital-associated influenza in a tertiary care adult Hospital in Singapore, 2011-2015","volume":"45","issn":"0304-4602","url":"http://www.annals.edu.sg/pdf/45VolNo9Sep2016/SHBC2016.pdf http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed17&NEWS=N&AN=612898364","abstract":"Background & Hypothesis: Hospital-associated influenza is known to contribute to morbidity and mortality among hospitalised patients. Method(s): We conducted a retrospective review of all patients with laboratory-confirmed influenza from January 2011 to December 2015, and compared community-associated (CA, laboratory-confirmed influenza \\textless=3 days after admission) with hospital-associated (HA, laboratory-confirmed \\textgreater3 days after admission) influenza. Result(s): There were 5729 patient-admissions (69% aged \\textgreater=65 years, 51% female and 3.3% of HA) with influenza A/H3 (59%), A/H1N1-2009 (16%), B (16%) and A/subtype-undetermined (9%) during the study period. HA cases were more likely to be of older age (P = 0.037), or have chronic medical conditions such as cerebrovascular disease (P \\textless0.001), congestive heart failure (P = 0.002), renal disease (P = 0.045), any malignancy (P \\textless0.001) or HIV infection (P \\textless0.001). The median length of stay after influenza diagnosis for HA influenza (8 days) was greater than that for CA influenza (4 days) (P \\textless0.001). A larger proportion of HA cases (18%) than CA (7%) cases needed ICU care or died (P \\textless0.001). On multivariate analysis, factors independently associated with HA influenza were comorbidities of cerebrovascular disease (AOR 2.85, 95% CI 1.78-4.56), congestive heart failure (AOR 1.57, 95% CI 1.05-2.35), any malignancy (AOR 2.85, 95% CI 1.70-4.79), and HIV infection (AOR 13.32, 95% CI 4.08-43.46). In contrast, chronic pulmonary disease (AOR 0.56, 95% CI 0.36- 0.86) and influenza B (AOR 0.58, 95% CI 0.39-0.88) were less common in HA influenza, after adjusting for age and gender. Discussion & Conclusion(s): Annual influenza vaccination should be actively promoted not only to patients with chronic medical conditions but also to healthcare workers attending to patients, to prevent HA influenza.","language":"English","number":"9 Supplement 1","journal":"Annals of the Academy of Medicine Singapore","author":[{"propositions":[],"lastnames":["Kyaw"],"firstnames":["W.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Aung"],"firstnames":["A.","H."],"suffixes":[]},{"propositions":[],"lastnames":["Loh"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Ho"],"firstnames":["H."],"suffixes":[]},{"propositions":[],"lastnames":["Chow"],"firstnames":["A."],"suffixes":[]}],"year":"2016","keywords":"*Influenza A virus (H1N1), *Singapore, *doctor patient relation, *nonhuman, *tertiary health care, Human immunodeficiency virus infection, adult, aged, cerebrovascular disease, chronic lung disease, comorbidity, congestive heart failure, controlled study, diagnosis, female, gender, health care personnel, hospital admission, human, influenza B, influenza vaccination, kidney disease, length of stay, major clinical study, male, malignant neoplastic disease, multivariate analysis, prevention, retrospective study","pages":"S82","bibtex":"@article{kyaw_characteristics_2016,\n\ttitle = {Characteristics of hospital-associated influenza in a tertiary care adult {Hospital} in {Singapore}, 2011-2015},\n\tvolume = {45},\n\tissn = {0304-4602},\n\turl = {http://www.annals.edu.sg/pdf/45VolNo9Sep2016/SHBC2016.pdf http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed17&NEWS=N&AN=612898364},\n\tabstract = {Background \\& Hypothesis: Hospital-associated influenza is known to contribute to morbidity and mortality among hospitalised patients. Method(s): We conducted a retrospective review of all patients with laboratory-confirmed influenza from January 2011 to December 2015, and compared community-associated (CA, laboratory-confirmed influenza {\\textless}=3 days after admission) with hospital-associated (HA, laboratory-confirmed {\\textgreater}3 days after admission) influenza. Result(s): There were 5729 patient-admissions (69\\% aged {\\textgreater}=65 years, 51\\% female and 3.3\\% of HA) with influenza A/H3 (59\\%), A/H1N1-2009 (16\\%), B (16\\%) and A/subtype-undetermined (9\\%) during the study period. HA cases were more likely to be of older age (P = 0.037), or have chronic medical conditions such as cerebrovascular disease (P {\\textless}0.001), congestive heart failure (P = 0.002), renal disease (P = 0.045), any malignancy (P {\\textless}0.001) or HIV infection (P {\\textless}0.001). The median length of stay after influenza diagnosis for HA influenza (8 days) was greater than that for CA influenza (4 days) (P {\\textless}0.001). A larger proportion of HA cases (18\\%) than CA (7\\%) cases needed ICU care or died (P {\\textless}0.001). On multivariate analysis, factors independently associated with HA influenza were comorbidities of cerebrovascular disease (AOR 2.85, 95\\% CI 1.78-4.56), congestive heart failure (AOR 1.57, 95\\% CI 1.05-2.35), any malignancy (AOR 2.85, 95\\% CI 1.70-4.79), and HIV infection (AOR 13.32, 95\\% CI 4.08-43.46). In contrast, chronic pulmonary disease (AOR 0.56, 95\\% CI 0.36- 0.86) and influenza B (AOR 0.58, 95\\% CI 0.39-0.88) were less common in HA influenza, after adjusting for age and gender. Discussion \\& Conclusion(s): Annual influenza vaccination should be actively promoted not only to patients with chronic medical conditions but also to healthcare workers attending to patients, to prevent HA influenza.},\n\tlanguage = {English},\n\tnumber = {9 Supplement 1},\n\tjournal = {Annals of the Academy of Medicine Singapore},\n\tauthor = {Kyaw, W. M. and Aung, A. 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