MDCT angiography for detection of pulmonary emboli: Comparison between equi-iodine doses of iomeprol 400 mgI/mL and iodixanol 320 mgI/mL. Langenberger, H., Friedrich, K., Plank, C., Matzek, W., Wolf, F., Storto, M., Schaefer-Prokop, C., & Herold, C. European Journal of Radiology, 2009. abstract bibtex Objectives: To compare iomeprol 400 and iodixanol 320 in pulmonary artery MDCTA in subjects with suspected pulmonary embolism. Methods: Eighty randomized subjects received equi-iodine intravenous doses (48 g) of iomeprol 400 (n = 40) or iodixanol 320 (n = 40), via power injector at 4 mL/s. Four-row (35 subjects) and 64-row (45 subjects) scanners were used. Lumen attenuation was determined on-site and by two off-site blinded readers in the main, lobar, segmental and subsegmental pulmonary arteries. Statistical comparison between groups was performed for demographics and lumen attenuation. Results: There were no between-group differences (p > 0.05) in demographics. Pulmonary artery attenuation was significantly (p ≤ 0.03) higher with iomeprol 400 for all readers. Attenuation quality was excellent in more patients after iomeprol 400 than after iodixanol-320 (80% vs. 62.5%; 82.5% vs. 77.5%; off-site readers 1 and 2, respectively). No safety concerns were noted. Conclusion: The greater iodine delivery rate achievable with iomeprol 400 compared to iodixanol-320 at equi-iodine dose and injection rate permits consistently greater attenuation at all levels of the pulmonary arterial tree. © 2008.
@article{
title = {MDCT angiography for detection of pulmonary emboli: Comparison between equi-iodine doses of iomeprol 400 mgI/mL and iodixanol 320 mgI/mL},
type = {article},
year = {2009},
identifiers = {[object Object]},
keywords = {Computed tomography (CT), angiography,Computed tomography (CT), contrast enhancement,Contrast media, comparative studies,Embolism, pulmonary,Pulmonary arteries, CT},
volume = {70},
id = {86b5a052-48c5-3956-87c8-8b10174709ce},
created = {2017-04-06T18:59:17.773Z},
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last_modified = {2017-04-06T18:59:17.773Z},
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abstract = {Objectives: To compare iomeprol 400 and iodixanol 320 in pulmonary artery MDCTA in subjects with suspected pulmonary embolism. Methods: Eighty randomized subjects received equi-iodine intravenous doses (48 g) of iomeprol 400 (n = 40) or iodixanol 320 (n = 40), via power injector at 4 mL/s. Four-row (35 subjects) and 64-row (45 subjects) scanners were used. Lumen attenuation was determined on-site and by two off-site blinded readers in the main, lobar, segmental and subsegmental pulmonary arteries. Statistical comparison between groups was performed for demographics and lumen attenuation. Results: There were no between-group differences (p > 0.05) in demographics. Pulmonary artery attenuation was significantly (p ≤ 0.03) higher with iomeprol 400 for all readers. Attenuation quality was excellent in more patients after iomeprol 400 than after iodixanol-320 (80% vs. 62.5%; 82.5% vs. 77.5%; off-site readers 1 and 2, respectively). No safety concerns were noted. Conclusion: The greater iodine delivery rate achievable with iomeprol 400 compared to iodixanol-320 at equi-iodine dose and injection rate permits consistently greater attenuation at all levels of the pulmonary arterial tree. © 2008.},
bibtype = {article},
author = {Langenberger, H. and Friedrich, K. and Plank, C. and Matzek, W. and Wolf, F. and Storto, M.L. and Schaefer-Prokop, C. and Herold, C.},
journal = {European Journal of Radiology},
number = {3}
}
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