The practice pattern of hepatitis b testing in rheumatoid arthritis patients: A cross-national comparison between US and Taiwan. Lin, T., Hashemi, N., Kim, S. C., Kao Yang, Y., Yoshida, K., Tedeschi, S., Desai, R., & Solomon, D. H. Arthritis Care & Research, March, 2017.
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OBJECTIVE: The Hepatitis B Virus (HBV) testing rates and patterns in rheumatoid arthritis (RA) patients starting disease modifying anti-rheumatic drugs (DMARDs) have not been well studied. We describe and compare the practice patterns of HBV testing among RA patients in U.S. and Taiwan. METHODS: We conducted a retrospective cohort study including RA patients starting first DMARD in U.S. or Taiwan. The first date patients newly received any DMARD was defined as the index date, and the 1-year period before the index date was the baseline period. HBV testing was defined as any of the following tests 1 year before or after the index date: HBsAg, HBsAb, HBcAb, HBeAg, HBeAb or HBV DNA. We calculated the HBV testing rate by year and used Poisson regression to calculate the testing rate ratio. RESULTS: We identified 14,568 RA patients in U.S. and 46,265 in Taiwan. The overall testing rate was 20.3% in U.S. and 24.5% in Taiwan, and gradually increased over the study period from 13.1% to 23.0% in the U.S. and 16.8% to 30.0% in Taiwan. More than one type of HBV test was used in 43.4% in the U.S. and 16.3% in Taiwan patients receiving tests. Results of Poisson regression found Taiwan had a 17% higher testing rate over U.S. during the follow-up period (crude rate ratio: 1.17; 95%CI 1.12-1.22). CONCLUSION: We found small differences in the HBV testing rates across U.S. and Taiwan. Although the rate gradually increased in the past decade, it remained low in both countries. This article is protected by copyright. All rights reserved.
@article{lin_practice_2017,
	title = {The practice pattern of hepatitis b testing in rheumatoid arthritis patients: {A} cross-national comparison between {US} and {Taiwan}},
	issn = {2151-4658},
	shorttitle = {The practice pattern of hepatitis b testing in rheumatoid arthritis patients},
	doi = {10.1002/acr.23241},
	abstract = {OBJECTIVE: The Hepatitis B Virus (HBV) testing rates and patterns in rheumatoid arthritis (RA) patients starting disease modifying anti-rheumatic drugs (DMARDs) have not been well studied. We describe and compare the practice patterns of HBV testing among RA patients in U.S. and Taiwan.
METHODS: We conducted a retrospective cohort study including RA patients starting first DMARD in U.S. or Taiwan. The first date patients newly received any DMARD was defined as the index date, and the 1-year period before the index date was the baseline period. HBV testing was defined as any of the following tests 1 year before or after the index date: HBsAg, HBsAb, HBcAb, HBeAg, HBeAb or HBV DNA. We calculated the HBV testing rate by year and used Poisson regression to calculate the testing rate ratio.
RESULTS: We identified 14,568 RA patients in U.S. and 46,265 in Taiwan. The overall testing rate was 20.3\% in U.S. and 24.5\% in Taiwan, and gradually increased over the study period from 13.1\% to 23.0\% in the U.S. and 16.8\% to 30.0\% in Taiwan. More than one type of HBV test was used in 43.4\% in the U.S. and 16.3\% in Taiwan patients receiving tests. Results of Poisson regression found Taiwan had a 17\% higher testing rate over U.S. during the follow-up period (crude rate ratio: 1.17; 95\%CI 1.12-1.22).
CONCLUSION: We found small differences in the HBV testing rates across U.S. and Taiwan. Although the rate gradually increased in the past decade, it remained low in both countries. This article is protected by copyright. All rights reserved.},
	language = {eng},
	journal = {Arthritis Care \& Research},
	author = {Lin, Tzu-Chieh and Hashemi, Nikroo and Kim, Seoyoung C. and Kao Yang, Yea-Huei and Yoshida, Kazuki and Tedeschi, Sara and Desai, Rishi and Solomon, Daniel H.},
	month = mar,
	year = {2017},
	pmid = {28320050},
	keywords = {DMARDs, Health Services Research, Hepatitis B, Rheumatoid arthritis, testing}
}

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