Response of monkey glabrous skin mechanoreceptors to random noise sequences: II. Dynamic stimulus state analysis. Looft, F. J. Somatosens Mot Res, 13(1):11--28, 1996. abstract bibtex The responses of monkey glabrous skin slowly adapting (SAI, Merkel cell), rapidly adapting (RA, Meissner) and Pacinian corpuscle (PC) mechanoreceptors were analyzed as a function of the instantaneous position, velocity, and acceleration of a dynamic stimulus. For these experiments, a vibrotactile punctate stimulator was driven by a non-repeating-noise sequence. The resulting data (sampled stimulus waveform, windowed impulse) were processed in several ways. Initially, input-output correlation analysis was implemented to generate spike-aligned averages of the stimulus waveform preceding and following impulse initiation. From this analysis, it was determined that dual-responding RA and PC afferents--that is, those afferents that responded to both indenting and extracting stimulus movements--universally responded in a nearly perfectly symmetrical manner to the stimulus. Subsequently, two-dimensional (position, velocity) state histograms were generated and used to assess mechanoreceptor dynamic stimulus sensitivities. From these state histograms, it was determined that the threshold for impulse initiation by SAI afferents was preferentially sensitive to the indentation position of the stimulus, with only a minor sensitivity to stimulus velocity. RA afferent thresholds were sensitive to a continuum of dynamic stimulus velocities and positions. At the extremes, RA afferent impulses could be initiated by either a highly indented, low-velocity stimulus or high-velocity stimulus with a limited indentation position. PC afferents appeared to be preferentially sensitive to a combination of stimulus velocity and acceleration, but the data-sampling interval was too coarse to adequately resolve the full range of dynamic stimulus sensitivities.
@article{ Looft96a,
author = {F. J. Looft},
title = {Response of monkey glabrous skin mechanoreceptors to random noise
sequences: {II. D}ynamic stimulus state analysis},
journal = {Somatosens Mot Res},
year = {1996},
volume = {13},
pages = {11--28},
number = {1},
abstract = {The responses of monkey glabrous skin slowly adapting (SAI, Merkel
cell), rapidly adapting (RA, Meissner) and Pacinian corpuscle (PC)
mechanoreceptors were analyzed as a function of the instantaneous
position, velocity, and acceleration of a dynamic stimulus. For these
experiments, a vibrotactile punctate stimulator was driven by a non-repeating-noise
sequence. The resulting data (sampled stimulus waveform, windowed
impulse) were processed in several ways. Initially, input-output
correlation analysis was implemented to generate spike-aligned averages
of the stimulus waveform preceding and following impulse initiation.
From this analysis, it was determined that dual-responding RA and
PC afferents--that is, those afferents that responded to both indenting
and extracting stimulus movements--universally responded in a nearly
perfectly symmetrical manner to the stimulus. Subsequently, two-dimensional
(position, velocity) state histograms were generated and used to
assess mechanoreceptor dynamic stimulus sensitivities. From these
state histograms, it was determined that the threshold for impulse
initiation by SAI afferents was preferentially sensitive to the indentation
position of the stimulus, with only a minor sensitivity to stimulus
velocity. RA afferent thresholds were sensitive to a continuum of
dynamic stimulus velocities and positions. At the extremes, RA afferent
impulses could be initiated by either a highly indented, low-velocity
stimulus or high-velocity stimulus with a limited indentation position.
PC afferents appeared to be preferentially sensitive to a combination
of stimulus velocity and acceleration, but the data-sampling interval
was too coarse to adequately resolve the full range of dynamic stimulus
sensitivities.},
institution = {Department of Electrical and Computer Engineering, Worcester Polytechnic
Institute, Worcester, Massachusetts 01609, USA. fjlooft@ee.wpi.edu},
keywords = {Afferent Pathways, physiology; Animals; Attention, physiology; Macaca
mulatta; Mechanoreceptors, physiology; Median Nerve, physiology;
Merkel Cells, physiology; Models, Neurological; Orientation, physiology;
Pacinian Corpuscles, physiology; Regression Analysis; Sensory Thresholds,
physiology; Signal Processing, Computer-Assisted; Skin, innervation;
Touch, physiology; Ulnar Nerve, physiology},
language = {eng},
medline-pst = {ppublish},
owner = {doyen},
pmid = {8725645},
timestamp = {2010.09.07}
}
Downloads: 0
{"_id":"nNfEFww3AsPQXJauX","bibbaseid":"looft-responseofmonkeyglabrousskinmechanoreceptorstorandomnoisesequencesiidynamicstimulusstateanalysis-1996","downloads":0,"creationDate":"2015-02-08T05:14:49.935Z","title":"Response of monkey glabrous skin mechanoreceptors to random noise sequences: II. Dynamic stimulus state analysis","author_short":["Looft, F.<nbsp>J."],"year":1996,"bibtype":"article","biburl":"http://cnslab.mb.jhu.edu/niebase.bib","bibdata":{"abstract":"The responses of monkey glabrous skin slowly adapting (SAI, Merkel cell), rapidly adapting (RA, Meissner) and Pacinian corpuscle (PC) mechanoreceptors were analyzed as a function of the instantaneous position, velocity, and acceleration of a dynamic stimulus. For these experiments, a vibrotactile punctate stimulator was driven by a non-repeating-noise sequence. The resulting data (sampled stimulus waveform, windowed impulse) were processed in several ways. Initially, input-output correlation analysis was implemented to generate spike-aligned averages of the stimulus waveform preceding and following impulse initiation. From this analysis, it was determined that dual-responding RA and PC afferents--that is, those afferents that responded to both indenting and extracting stimulus movements--universally responded in a nearly perfectly symmetrical manner to the stimulus. Subsequently, two-dimensional (position, velocity) state histograms were generated and used to assess mechanoreceptor dynamic stimulus sensitivities. From these state histograms, it was determined that the threshold for impulse initiation by SAI afferents was preferentially sensitive to the indentation position of the stimulus, with only a minor sensitivity to stimulus velocity. RA afferent thresholds were sensitive to a continuum of dynamic stimulus velocities and positions. At the extremes, RA afferent impulses could be initiated by either a highly indented, low-velocity stimulus or high-velocity stimulus with a limited indentation position. PC afferents appeared to be preferentially sensitive to a combination of stimulus velocity and acceleration, but the data-sampling interval was too coarse to adequately resolve the full range of dynamic stimulus sensitivities.","author":["Looft, F. J."],"author_short":["Looft, F.<nbsp>J."],"bibtex":"@article{ Looft96a,\n author = {F. J. Looft},\n title = {Response of monkey glabrous skin mechanoreceptors to random noise\n\tsequences: {II. D}ynamic stimulus state analysis},\n journal = {Somatosens Mot Res},\n year = {1996},\n volume = {13},\n pages = {11--28},\n number = {1},\n abstract = {The responses of monkey glabrous skin slowly adapting (SAI, Merkel\n\tcell), rapidly adapting (RA, Meissner) and Pacinian corpuscle (PC)\n\tmechanoreceptors were analyzed as a function of the instantaneous\n\tposition, velocity, and acceleration of a dynamic stimulus. For these\n\texperiments, a vibrotactile punctate stimulator was driven by a non-repeating-noise\n\tsequence. The resulting data (sampled stimulus waveform, windowed\n\timpulse) were processed in several ways. Initially, input-output\n\tcorrelation analysis was implemented to generate spike-aligned averages\n\tof the stimulus waveform preceding and following impulse initiation.\n\tFrom this analysis, it was determined that dual-responding RA and\n\tPC afferents--that is, those afferents that responded to both indenting\n\tand extracting stimulus movements--universally responded in a nearly\n\tperfectly symmetrical manner to the stimulus. Subsequently, two-dimensional\n\t(position, velocity) state histograms were generated and used to\n\tassess mechanoreceptor dynamic stimulus sensitivities. From these\n\tstate histograms, it was determined that the threshold for impulse\n\tinitiation by SAI afferents was preferentially sensitive to the indentation\n\tposition of the stimulus, with only a minor sensitivity to stimulus\n\tvelocity. RA afferent thresholds were sensitive to a continuum of\n\tdynamic stimulus velocities and positions. At the extremes, RA afferent\n\timpulses could be initiated by either a highly indented, low-velocity\n\tstimulus or high-velocity stimulus with a limited indentation position.\n\tPC afferents appeared to be preferentially sensitive to a combination\n\tof stimulus velocity and acceleration, but the data-sampling interval\n\twas too coarse to adequately resolve the full range of dynamic stimulus\n\tsensitivities.},\n institution = {Department of Electrical and Computer Engineering, Worcester Polytechnic\n\tInstitute, Worcester, Massachusetts 01609, USA. fjlooft@ee.wpi.edu},\n keywords = {Afferent Pathways, physiology; Animals; Attention, physiology; Macaca\n\tmulatta; Mechanoreceptors, physiology; Median Nerve, physiology;\n\tMerkel Cells, physiology; Models, Neurological; Orientation, physiology;\n\tPacinian Corpuscles, physiology; Regression Analysis; Sensory Thresholds,\n\tphysiology; Signal Processing, Computer-Assisted; Skin, innervation;\n\tTouch, physiology; Ulnar Nerve, physiology},\n language = {eng},\n medline-pst = {ppublish},\n owner = {doyen},\n pmid = {8725645},\n timestamp = {2010.09.07}\n}","bibtype":"article","id":"Looft96a","institution":"Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, Massachusetts 01609, USA. fjlooft@ee.wpi.edu","journal":"Somatosens Mot Res","key":"Looft96a","keywords":"Afferent Pathways, physiology; Animals; Attention, physiology; Macaca mulatta; Mechanoreceptors, physiology; Median Nerve, physiology; Merkel Cells, physiology; Models, Neurological; Orientation, physiology; Pacinian Corpuscles, physiology; Regression Analysis; Sensory Thresholds, physiology; Signal Processing, Computer-Assisted; Skin, innervation; Touch, physiology; Ulnar Nerve, physiology","language":"eng","medline-pst":"ppublish","number":"1","owner":"doyen","pages":"11--28","pmid":"8725645","timestamp":"2010.09.07","title":"Response of monkey glabrous skin mechanoreceptors to random noise sequences: II. Dynamic stimulus state analysis","type":"article","volume":"13","year":"1996","bibbaseid":"looft-responseofmonkeyglabrousskinmechanoreceptorstorandomnoisesequencesiidynamicstimulusstateanalysis-1996","role":"author","urls":{},"keyword":["Afferent Pathways","physiology; Animals; Attention","physiology; Macaca mulatta; Mechanoreceptors","physiology; Median Nerve","physiology; Merkel Cells","physiology; Models","Neurological; Orientation","physiology; Pacinian Corpuscles","physiology; Regression Analysis; Sensory Thresholds","physiology; Signal Processing","Computer-Assisted; Skin","innervation; Touch","physiology; Ulnar Nerve","physiology"],"downloads":0},"search_terms":["response","monkey","glabrous","skin","mechanoreceptors","random","noise","sequences","dynamic","stimulus","state","analysis","looft"],"keywords":["afferent pathways","physiology; animals; attention","physiology; macaca mulatta; mechanoreceptors","physiology; median nerve","physiology; merkel cells","physiology; models","neurological; orientation","physiology; pacinian corpuscles","physiology; regression analysis; sensory thresholds","physiology; signal processing","computer-assisted; skin","innervation; touch","physiology; ulnar nerve","physiology"],"authorIDs":[],"dataSources":["ErLXoH8mqSjESnrN5"]}