Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience. Lu, Y., Jansen, J. F., Stambuk, H. E., Gupta, G., Lee, N., Gonen, M., Moreira, A., Mazaheri, Y., Patel, S. G., Deasy, J. O., Shah, J. P., & Shukla-Dave, A. J Comput Assist Tomogr, 37(3):346-52, 2013. Lu, Yonggang Jansen, Jacobus F A Stambuk, Hilda E Gupta, Gaorav Lee, Nancy Gonen, Mithat Moreira, Andre Mazaheri, Yousef Patel, Snehal G Deasy, Joseph O Shah, Jatin P Shukla-Dave, Amita eng P30 CA008748/CA/NCI NIH HHS/ R01 CA115895/CA/NCI NIH HHS/ 1 R01 CA115895/CA/NCI NIH HHS/ Comparative Study Research Support, N.I.H., Extramural 2013/05/16 06:00 J Comput Assist Tomogr. 2013 May-Jun;37(3):346-52. doi: 10.1097/RCT.0b013e318282d935.
Paper doi abstract bibtex OBJECTIVE: This study aimed to use intravoxel incoherent motion (IVIM) imaging for investigating differences between primary head and neck tumors and nodal metastases and to evaluate IVIM efficacy in predicting outcome. METHODS: Sixteen patients with head and neck cancer underwent IVIM diffusion-weighted imaging on a 1.5-T magnetic resonance imaging scanner. The significance of parametric difference between primary tumors and metastatic nodes were tested. Probabilities of progression-free survival and overall survival were estimated using the Kaplan-Meier method. RESULTS: In comparison with metastatic nodes, the primary tumors had significantly higher vascular volume fraction (f) (P < 0.0009) and lower diffusion coefficient (D) (P < 0.0002). Patients with lower SD for D had prolonged progression-free survival and overall survival (P < 0.05). CONCLUSIONS: Pretreatment IVIM measures were feasible in investigating the physiologic differences between the 2 tumor tissues. After appropriate validation, these findings might be useful in optimizing treatment planning and improving patient care.
@article{RN161,
author = {Lu, Y. and Jansen, J. F. and Stambuk, H. E. and Gupta, G. and Lee, N. and Gonen, M. and Moreira, A. and Mazaheri, Y. and Patel, S. G. and Deasy, J. O. and Shah, J. P. and Shukla-Dave, A.},
title = {Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience},
journal = {J Comput Assist Tomogr},
volume = {37},
number = {3},
pages = {346-52},
note = {Lu, Yonggang
Jansen, Jacobus F A
Stambuk, Hilda E
Gupta, Gaorav
Lee, Nancy
Gonen, Mithat
Moreira, Andre
Mazaheri, Yousef
Patel, Snehal G
Deasy, Joseph O
Shah, Jatin P
Shukla-Dave, Amita
eng
P30 CA008748/CA/NCI NIH HHS/
R01 CA115895/CA/NCI NIH HHS/
1 R01 CA115895/CA/NCI NIH HHS/
Comparative Study
Research Support, N.I.H., Extramural
2013/05/16 06:00
J Comput Assist Tomogr. 2013 May-Jun;37(3):346-52. doi: 10.1097/RCT.0b013e318282d935.},
abstract = {OBJECTIVE: This study aimed to use intravoxel incoherent motion (IVIM) imaging for investigating differences between primary head and neck tumors and nodal metastases and to evaluate IVIM efficacy in predicting outcome. METHODS: Sixteen patients with head and neck cancer underwent IVIM diffusion-weighted imaging on a 1.5-T magnetic resonance imaging scanner. The significance of parametric difference between primary tumors and metastatic nodes were tested. Probabilities of progression-free survival and overall survival were estimated using the Kaplan-Meier method. RESULTS: In comparison with metastatic nodes, the primary tumors had significantly higher vascular volume fraction (f) (P < 0.0009) and lower diffusion coefficient (D) (P < 0.0002). Patients with lower SD for D had prolonged progression-free survival and overall survival (P < 0.05). CONCLUSIONS: Pretreatment IVIM measures were feasible in investigating the physiologic differences between the 2 tumor tissues. After appropriate validation, these findings might be useful in optimizing treatment planning and improving patient care.},
keywords = {Adult
Biopsy
Data Interpretation, Statistical
Diffusion Magnetic Resonance Imaging/*methods
Echo-Planar Imaging
Female
Head and Neck Neoplasms/*pathology/therapy
Humans
Lymphatic Metastasis/*pathology
Male
Middle Aged
Retrospective Studies
Survival Analysis},
ISSN = {1532-3145 (Electronic)
0363-8715 (Linking)},
DOI = {10.1097/RCT.0b013e318282d935},
url = {http://www.ncbi.nlm.nih.gov/pubmed/23674004
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655331/pdf/nihms-435487.pdf},
year = {2013},
type = {Journal Article}
}
Downloads: 0
{"_id":"QFS7oDzLoAXTmjZHf","bibbaseid":"lu-jansen-stambuk-gupta-lee-gonen-moreira-mazaheri-etal-comparingprimarytumorsandmetastaticnodesinheadandneckcancerusingintravoxelincoherentmotionimagingapreliminaryexperience-2013","downloads":0,"creationDate":"2017-09-02T18:10:13.503Z","title":"Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience","author_short":["Lu, Y.","Jansen, J. F.","Stambuk, H. E.","Gupta, G.","Lee, N.","Gonen, M.","Moreira, A.","Mazaheri, Y.","Patel, S. G.","Deasy, J. O.","Shah, J. P.","Shukla-Dave, A."],"year":2013,"bibtype":"article","biburl":"https://raw.githubusercontent.com/jansenjfa1/bibbase.github.io/master/jansenjfa.bib","bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Lu"],"firstnames":["Y."],"suffixes":[]},{"propositions":[],"lastnames":["Jansen"],"firstnames":["J.","F."],"suffixes":[]},{"propositions":[],"lastnames":["Stambuk"],"firstnames":["H.","E."],"suffixes":[]},{"propositions":[],"lastnames":["Gupta"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Lee"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["Gonen"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Moreira"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Mazaheri"],"firstnames":["Y."],"suffixes":[]},{"propositions":[],"lastnames":["Patel"],"firstnames":["S.","G."],"suffixes":[]},{"propositions":[],"lastnames":["Deasy"],"firstnames":["J.","O."],"suffixes":[]},{"propositions":[],"lastnames":["Shah"],"firstnames":["J.","P."],"suffixes":[]},{"propositions":[],"lastnames":["Shukla-Dave"],"firstnames":["A."],"suffixes":[]}],"title":"Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience","journal":"J Comput Assist Tomogr","volume":"37","number":"3","pages":"346-52","note":"Lu, Yonggang Jansen, Jacobus F A Stambuk, Hilda E Gupta, Gaorav Lee, Nancy Gonen, Mithat Moreira, Andre Mazaheri, Yousef Patel, Snehal G Deasy, Joseph O Shah, Jatin P Shukla-Dave, Amita eng P30 CA008748/CA/NCI NIH HHS/ R01 CA115895/CA/NCI NIH HHS/ 1 R01 CA115895/CA/NCI NIH HHS/ Comparative Study Research Support, N.I.H., Extramural 2013/05/16 06:00 J Comput Assist Tomogr. 2013 May-Jun;37(3):346-52. doi: 10.1097/RCT.0b013e318282d935.","abstract":"OBJECTIVE: This study aimed to use intravoxel incoherent motion (IVIM) imaging for investigating differences between primary head and neck tumors and nodal metastases and to evaluate IVIM efficacy in predicting outcome. METHODS: Sixteen patients with head and neck cancer underwent IVIM diffusion-weighted imaging on a 1.5-T magnetic resonance imaging scanner. The significance of parametric difference between primary tumors and metastatic nodes were tested. Probabilities of progression-free survival and overall survival were estimated using the Kaplan-Meier method. RESULTS: In comparison with metastatic nodes, the primary tumors had significantly higher vascular volume fraction (f) (P < 0.0009) and lower diffusion coefficient (D) (P < 0.0002). Patients with lower SD for D had prolonged progression-free survival and overall survival (P < 0.05). CONCLUSIONS: Pretreatment IVIM measures were feasible in investigating the physiologic differences between the 2 tumor tissues. After appropriate validation, these findings might be useful in optimizing treatment planning and improving patient care.","keywords":"Adult Biopsy Data Interpretation, Statistical Diffusion Magnetic Resonance Imaging/*methods Echo-Planar Imaging Female Head and Neck Neoplasms/*pathology/therapy Humans Lymphatic Metastasis/*pathology Male Middle Aged Retrospective Studies Survival Analysis","issn":"1532-3145 (Electronic) 0363-8715 (Linking)","doi":"10.1097/RCT.0b013e318282d935","url":"http://www.ncbi.nlm.nih.gov/pubmed/23674004 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655331/pdf/nihms-435487.pdf","year":"2013","bibtex":"@article{RN161,\n author = {Lu, Y. and Jansen, J. F. and Stambuk, H. E. and Gupta, G. and Lee, N. and Gonen, M. and Moreira, A. and Mazaheri, Y. and Patel, S. G. and Deasy, J. O. and Shah, J. P. and Shukla-Dave, A.},\n title = {Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience},\n journal = {J Comput Assist Tomogr},\n volume = {37},\n number = {3},\n pages = {346-52},\n note = {Lu, Yonggang\nJansen, Jacobus F A\nStambuk, Hilda E\nGupta, Gaorav\nLee, Nancy\nGonen, Mithat\nMoreira, Andre\nMazaheri, Yousef\nPatel, Snehal G\nDeasy, Joseph O\nShah, Jatin P\nShukla-Dave, Amita\neng\nP30 CA008748/CA/NCI NIH HHS/\nR01 CA115895/CA/NCI NIH HHS/\n1 R01 CA115895/CA/NCI NIH HHS/\nComparative Study\nResearch Support, N.I.H., Extramural\n2013/05/16 06:00\nJ Comput Assist Tomogr. 2013 May-Jun;37(3):346-52. doi: 10.1097/RCT.0b013e318282d935.},\n abstract = {OBJECTIVE: This study aimed to use intravoxel incoherent motion (IVIM) imaging for investigating differences between primary head and neck tumors and nodal metastases and to evaluate IVIM efficacy in predicting outcome. METHODS: Sixteen patients with head and neck cancer underwent IVIM diffusion-weighted imaging on a 1.5-T magnetic resonance imaging scanner. The significance of parametric difference between primary tumors and metastatic nodes were tested. Probabilities of progression-free survival and overall survival were estimated using the Kaplan-Meier method. RESULTS: In comparison with metastatic nodes, the primary tumors had significantly higher vascular volume fraction (f) (P < 0.0009) and lower diffusion coefficient (D) (P < 0.0002). Patients with lower SD for D had prolonged progression-free survival and overall survival (P < 0.05). CONCLUSIONS: Pretreatment IVIM measures were feasible in investigating the physiologic differences between the 2 tumor tissues. After appropriate validation, these findings might be useful in optimizing treatment planning and improving patient care.},\n keywords = {Adult\nBiopsy\nData Interpretation, Statistical\nDiffusion Magnetic Resonance Imaging/*methods\nEcho-Planar Imaging\nFemale\nHead and Neck Neoplasms/*pathology/therapy\nHumans\nLymphatic Metastasis/*pathology\nMale\nMiddle Aged\nRetrospective Studies\nSurvival Analysis},\n ISSN = {1532-3145 (Electronic)\n0363-8715 (Linking)},\n DOI = {10.1097/RCT.0b013e318282d935},\n url = {http://www.ncbi.nlm.nih.gov/pubmed/23674004\nhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655331/pdf/nihms-435487.pdf},\n year = {2013},\n type = {Journal Article}\n}\n\n","author_short":["Lu, Y.","Jansen, J. F.","Stambuk, H. E.","Gupta, G.","Lee, N.","Gonen, M.","Moreira, A.","Mazaheri, Y.","Patel, S. G.","Deasy, J. O.","Shah, J. P.","Shukla-Dave, A."],"key":"RN161","id":"RN161","bibbaseid":"lu-jansen-stambuk-gupta-lee-gonen-moreira-mazaheri-etal-comparingprimarytumorsandmetastaticnodesinheadandneckcancerusingintravoxelincoherentmotionimagingapreliminaryexperience-2013","role":"author","urls":{"Paper":"http://www.ncbi.nlm.nih.gov/pubmed/23674004 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655331/pdf/nihms-435487.pdf"},"keyword":["Adult Biopsy Data Interpretation","Statistical Diffusion Magnetic Resonance Imaging/*methods Echo-Planar Imaging Female Head and Neck Neoplasms/*pathology/therapy Humans Lymphatic Metastasis/*pathology Male Middle Aged Retrospective Studies Survival Analysis"],"metadata":{"authorlinks":{"jansen, j":"https://www.jansenjfa.com/publications/"}},"downloads":0,"html":""},"search_terms":["comparing","primary","tumors","metastatic","nodes","head","neck","cancer","using","intravoxel","incoherent","motion","imaging","preliminary","experience","lu","jansen","stambuk","gupta","lee","gonen","moreira","mazaheri","patel","deasy","shah","shukla-dave"],"keywords":["adult biopsy data interpretation","statistical diffusion magnetic resonance imaging/*methods echo-planar imaging female head and neck neoplasms/*pathology/therapy humans lymphatic metastasis/*pathology male middle aged retrospective studies survival analysis"],"authorIDs":["TEAWLnKpXtQE8hs6C"],"dataSources":["TCkfRWJAZvbLAZi29"]}