Clinical Relevance of Left Atrial Strain to Predict Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis. Ma, X., Boldt, L., Zhang, Y., Zhu, M., Hu, B., Parwani, A., Belyavskiy, E., Radha Krishnan, A., K., Krisper, M., Köhncke, C., Osmanoglou, E., Kropf, M., Lacour, P., Blaschke, F., Edelmann, F., Tschöpe, C., Haverkamp, W., Pieske-Kraigher, E., Pieske, B., & Morris, D., A. Echocardiography, 2016.
Clinical Relevance of Left Atrial Strain to Predict Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis [pdf]Paper  Clinical Relevance of Left Atrial Strain to Predict Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis [link]Website  abstract   bibtex   
BACKGROUND: The purpose of this meta-analysis was to analyze the clinical relevance of left atrial (LA) strain to predict recurrence of atrial fibrillation (AF) after catheter ablation (CA).\n\nMETHODS AND RESULTS: We searched in different databases (Medline, EMBASE, and Cochrane) prospective studies that analyzed LA strain before CA. Eight studies (2 with only paroxysmal AF and 6 with mixed population of paroxysmal and persistent AF) were included in the final analysis (total patient number = 686). Patients with recurrence of AF were principally characterized by lower LA strain in comparison with those without AF recurrence (mean 18.4% [range 8.8-24.5%] versus 25.3% [13.6-32.7%], weighted mean difference -4.89% [95% CI -5.83% to -3.95%], P < 0.001). In addition, receiver operating curves shown that LA strain was strongly associated with recurrence of AF after CA (weighted mean: AUC 0.798 [95% CI 0.700-0.943], cutoff 22.8% [18.8-30%], sensitivity 78% [65-86%], and specificity 75% [66-100%]). In line, these results were similar using LA strain with QRS-analysis and P-analysis as well as using different software package such as Echo-Pac, QLab, TomTec, and VVI.\n\nCONCLUSION: In patients with AF candidate for CA, the analysis of the LA using LA strain could be of great usefulness to identify patients with high risk of AF recurrence. Nonetheless, further studies are needed to establish the clinical relevance of LA strain in patients with persistent AF.
@article{
 title = {Clinical Relevance of Left Atrial Strain to Predict Recurrence of Atrial Fibrillation after Catheter Ablation: A Meta-Analysis},
 type = {article},
 year = {2016},
 identifiers = {[object Object]},
 keywords = {af,atrial fi brillation,ca,catheter ablation,in,is variable,left atrial,paroxysmal atrial fi b-,patients with persistent and,rillation,strain,the success rate of,with rates that range},
 pages = {n/a-n/a},
 websites = {http://doi.wiley.com/10.1111/echo.13184},
 id = {1654b733-9fb8-372f-9eed-39bf0d5150ec},
 created = {2017-09-02T09:00:13.876Z},
 file_attached = {true},
 profile_id = {6b1939a3-fffe-398d-b61e-1eb0fac93911},
 last_modified = {2017-09-29T19:25:42.755Z},
 read = {false},
 starred = {false},
 authored = {true},
 confirmed = {true},
 hidden = {false},
 private_publication = {false},
 abstract = {BACKGROUND: The purpose of this meta-analysis was to analyze the clinical relevance of left atrial (LA) strain to predict recurrence of atrial fibrillation (AF) after catheter ablation (CA).\n\nMETHODS AND RESULTS: We searched in different databases (Medline, EMBASE, and Cochrane) prospective studies that analyzed LA strain before CA. Eight studies (2 with only paroxysmal AF and 6 with mixed population of paroxysmal and persistent AF) were included in the final analysis (total patient number = 686). Patients with recurrence of AF were principally characterized by lower LA strain in comparison with those without AF recurrence (mean 18.4% [range 8.8-24.5%] versus 25.3% [13.6-32.7%], weighted mean difference -4.89% [95% CI -5.83% to -3.95%], P < 0.001). In addition, receiver operating curves shown that LA strain was strongly associated with recurrence of AF after CA (weighted mean: AUC 0.798 [95% CI 0.700-0.943], cutoff 22.8% [18.8-30%], sensitivity 78% [65-86%], and specificity 75% [66-100%]). In line, these results were similar using LA strain with QRS-analysis and P-analysis as well as using different software package such as Echo-Pac, QLab, TomTec, and VVI.\n\nCONCLUSION: In patients with AF candidate for CA, the analysis of the LA using LA strain could be of great usefulness to identify patients with high risk of AF recurrence. Nonetheless, further studies are needed to establish the clinical relevance of LA strain in patients with persistent AF.},
 bibtype = {article},
 author = {Ma, Xin-Xin and Boldt, Leif-Hendrik and Zhang, Yue-Li and Zhu, Meng-Ruo and Hu, Bing and Parwani, Abdul and Belyavskiy, Evgeny and Radha Krishnan, Aravind K. and Krisper, Maximilian and Köhncke, Clemens and Osmanoglou, Engin and Kropf, Martin and Lacour, Philipp and Blaschke, Florian and Edelmann, Frank and Tschöpe, Carsten and Haverkamp, Wilhelm and Pieske-Kraigher, Elisabeth and Pieske, Burkert and Morris, Daniel A.},
 journal = {Echocardiography}
}
Downloads: 0