@article{
 title = {Screening women with a family history of breast cancer--results from the British Familial Breast Cancer Group},
 type = {article},
 year = {2000},
 identifiers = {[object Object]},
 keywords = {Adult,Breast Neoplasms/*diagnosis/epidemiology/*genetics,Female,Great Britain/epidemiology,Human,Incidence,Middle Age,Prevalence},
 pages = {149-52.},
 volume = {26},
 id = {6c6eace6-a369-3e31-b103-3d3ba99fea26},
 created = {2017-06-19T13:44:09.892Z},
 file_attached = {false},
 profile_id = {de68dde1-2ff3-3a4e-a214-ef424d0c7646},
 group_id = {b2078731-0913-33b9-8902-a53629a24e83},
 last_modified = {2017-06-19T13:44:10.003Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {Journal Article},
 notes = {<m:note>eng<m:linebreak/>Journal Article</m:note>},
 abstract = {AIMS: To determine the efficacy of screening women under age 50 with a significant family history of breast cancer. METHODS: Results from 22 Breast Units in the UK identified as being able to provide data were surveyed and pooled through regional data managers or consultant breast specialists. RESULTS: Data relating to 8783 women screened and 9075 woman years of follow-up was analysed. Cancer incidence was 11.3/1000/year. The rate of cancer detection was 4. 78/1000 at prevalent screening and 4.52/1000 at incident screening. Median age at diagnosis was 43 years. Interval cancers presented at a rate of 2.45/1000. Comparison with the National Health Service Breast Screening Programme for women aged 50-64 revealed a similar rate of cancer detection and a similar incidence of ductal carcinoma in situ. The pathological features of screen-detected cancers in this study strongly suggest that prognosis for these women is more favourable than if they had presented symptomatically. CONCLUSIONS: This study provides evidence to suggest that screening young women with a significant family history of breast cancer is effective and that a survival benefit can be expected. As a result the British Familial Breast Cancer Group proposes a co-ordinated prospective observational study.},
 bibtype = {article},
 author = {Macmillan, R D},
 journal = {Eur J Surg Oncol},
 number = {2}
}

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METHODS: Results from 22 Breast Units in the UK identified as being able to provide data were surveyed and pooled through regional data managers or consultant breast specialists. RESULTS: Data relating to 8783 women screened and 9075 woman years of follow-up was analysed. Cancer incidence was 11.3/1000/year. The rate of cancer detection was 4. 78/1000 at prevalent screening and 4.52/1000 at incident screening. Median age at diagnosis was 43 years. Interval cancers presented at a rate of 2.45/1000. Comparison with the National Health Service Breast Screening Programme for women aged 50-64 revealed a similar rate of cancer detection and a similar incidence of ductal carcinoma in situ. The pathological features of screen-detected cancers in this study strongly suggest that prognosis for these women is more favourable than if they had presented symptomatically. CONCLUSIONS: This study provides evidence to suggest that screening young women with a significant family history of breast cancer is effective and that a survival benefit can be expected. As a result the British Familial Breast Cancer Group proposes a co-ordinated prospective observational study.","bibtype":"article","author":"Macmillan, R D","journal":"Eur J Surg Oncol","number":"2","bibtex":"@article{\n title = {Screening women with a family history of breast cancer--results from the British Familial Breast Cancer Group},\n type = {article},\n year = {2000},\n identifiers = {[object Object]},\n keywords = {Adult,Breast Neoplasms/*diagnosis/epidemiology/*genetics,Female,Great Britain/epidemiology,Human,Incidence,Middle Age,Prevalence},\n pages = {149-52.},\n volume = {26},\n id = {6c6eace6-a369-3e31-b103-3d3ba99fea26},\n created = {2017-06-19T13:44:09.892Z},\n file_attached = {false},\n profile_id = {de68dde1-2ff3-3a4e-a214-ef424d0c7646},\n group_id = {b2078731-0913-33b9-8902-a53629a24e83},\n last_modified = {2017-06-19T13:44:10.003Z},\n read = {false},\n starred = {false},\n authored = {false},\n confirmed = {true},\n hidden = {false},\n source_type = {Journal Article},\n notes = {<m:note>eng<m:linebreak/>Journal Article</m:note>},\n abstract = {AIMS: To determine the efficacy of screening women under age 50 with a significant family history of breast cancer. 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