An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers. Madhun, A. S., Akselsen, P. E., Sjursen, H., Pedersen, G., Svindland, S., Nostbakken, J. K., Nilsen, M., Mohn, K., Jul-Larsen, A., Smith, I., Major, D., Wood, J., & Cox, R. J. Vaccine, 29(2):266–273, December, 2010. ![An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Mass vaccination was the most effective prophylaxis for protecting the population during the influenza H1N1 pandemic. We have evaluated the tolerability, immunogenicity and kinetics of the antibody response to a monovalent oil-in-water (AS03) adjuvanted human pandemic split influenza A/California/7/2009 H1N1 (3.75 mu g haemagglutinin) vaccine in health care workers. Vaccination elicited a rapid and early protective level of haemagglutination inhibition antibody from 6 to 7 days post vaccination, and by 14 to 21 days post vaccination, up to 98% of vaccinees had protective antibody titres which persisted for at least 3 months in 84-92% of subjects. A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic. (C) 2010 Elsevier Ltd. All rights reserved.
@article{madhun_adjuvanted_2010,
title = {An adjuvanted pandemic influenza {H1N1} vaccine provides early and long term protection in health care workers},
volume = {29},
issn = {0264-410X},
url = {://WOS:000287057300015},
doi = {10.1016/j.vaccine.2010.10.038},
abstract = {Mass vaccination was the most effective prophylaxis for protecting the population during the influenza H1N1 pandemic. We have evaluated the tolerability, immunogenicity and kinetics of the antibody response to a monovalent oil-in-water (AS03) adjuvanted human pandemic split influenza A/California/7/2009 H1N1 (3.75 mu g haemagglutinin) vaccine in health care workers. Vaccination elicited a rapid and early protective level of haemagglutination inhibition antibody from 6 to 7 days post vaccination, and by 14 to 21 days post vaccination, up to 98\% of vaccinees had protective antibody titres which persisted for at least 3 months in 84-92\% of subjects. A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic. (C) 2010 Elsevier Ltd. All rights reserved.},
language = {English},
number = {2},
journal = {Vaccine},
author = {Madhun, A. S. and Akselsen, P. E. and Sjursen, H. and Pedersen, G. and Svindland, S. and Nostbakken, J. K. and Nilsen, M. and Mohn, K. and Jul-Larsen, A. and Smith, I. and Major, D. and Wood, J. and Cox, R. J.},
month = dec,
year = {2010},
keywords = {Healthcare worker, Immunology, Pandemic influenza H1N1, Research \& Experimental Medicine, Vaccine, a/duck/singapore/97 h5n3 vaccine, antibody, immunity, immunogenicity, mf59-adjuvanted influenza, safety, trial, viruses},
pages = {266--273},
}
Downloads: 0
{"_id":"6wpYsJnuTvjkP7sZA","bibbaseid":"madhun-akselsen-sjursen-pedersen-svindland-nostbakken-nilsen-mohn-etal-anadjuvantedpandemicinfluenzah1n1vaccineprovidesearlyandlongtermprotectioninhealthcareworkers-2010","authorIDs":[],"author_short":["Madhun, A. S.","Akselsen, P. E.","Sjursen, H.","Pedersen, G.","Svindland, S.","Nostbakken, J. K.","Nilsen, M.","Mohn, K.","Jul-Larsen, A.","Smith, I.","Major, D.","Wood, J.","Cox, R. J."],"bibdata":{"bibtype":"article","type":"article","title":"An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers","volume":"29","issn":"0264-410X","url":"://WOS:000287057300015","doi":"10.1016/j.vaccine.2010.10.038","abstract":"Mass vaccination was the most effective prophylaxis for protecting the population during the influenza H1N1 pandemic. We have evaluated the tolerability, immunogenicity and kinetics of the antibody response to a monovalent oil-in-water (AS03) adjuvanted human pandemic split influenza A/California/7/2009 H1N1 (3.75 mu g haemagglutinin) vaccine in health care workers. Vaccination elicited a rapid and early protective level of haemagglutination inhibition antibody from 6 to 7 days post vaccination, and by 14 to 21 days post vaccination, up to 98% of vaccinees had protective antibody titres which persisted for at least 3 months in 84-92% of subjects. A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic. (C) 2010 Elsevier Ltd. All rights reserved.","language":"English","number":"2","journal":"Vaccine","author":[{"propositions":[],"lastnames":["Madhun"],"firstnames":["A.","S."],"suffixes":[]},{"propositions":[],"lastnames":["Akselsen"],"firstnames":["P.","E."],"suffixes":[]},{"propositions":[],"lastnames":["Sjursen"],"firstnames":["H."],"suffixes":[]},{"propositions":[],"lastnames":["Pedersen"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Svindland"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Nostbakken"],"firstnames":["J.","K."],"suffixes":[]},{"propositions":[],"lastnames":["Nilsen"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Mohn"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Jul-Larsen"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Smith"],"firstnames":["I."],"suffixes":[]},{"propositions":[],"lastnames":["Major"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Wood"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Cox"],"firstnames":["R.","J."],"suffixes":[]}],"month":"December","year":"2010","keywords":"Healthcare worker, Immunology, Pandemic influenza H1N1, Research & Experimental Medicine, Vaccine, a/duck/singapore/97 h5n3 vaccine, antibody, immunity, immunogenicity, mf59-adjuvanted influenza, safety, trial, viruses","pages":"266–273","bibtex":"@article{madhun_adjuvanted_2010,\n\ttitle = {An adjuvanted pandemic influenza {H1N1} vaccine provides early and long term protection in health care workers},\n\tvolume = {29},\n\tissn = {0264-410X},\n\turl = {://WOS:000287057300015},\n\tdoi = {10.1016/j.vaccine.2010.10.038},\n\tabstract = {Mass vaccination was the most effective prophylaxis for protecting the population during the influenza H1N1 pandemic. We have evaluated the tolerability, immunogenicity and kinetics of the antibody response to a monovalent oil-in-water (AS03) adjuvanted human pandemic split influenza A/California/7/2009 H1N1 (3.75 mu g haemagglutinin) vaccine in health care workers. Vaccination elicited a rapid and early protective level of haemagglutination inhibition antibody from 6 to 7 days post vaccination, and by 14 to 21 days post vaccination, up to 98\\% of vaccinees had protective antibody titres which persisted for at least 3 months in 84-92\\% of subjects. A rapid induction of protective antibody is important in reducing community spread of pandemic influenza and in helping maintain the integrity of the health care system during the pandemic. (C) 2010 Elsevier Ltd. All rights reserved.},\n\tlanguage = {English},\n\tnumber = {2},\n\tjournal = {Vaccine},\n\tauthor = {Madhun, A. S. and Akselsen, P. E. and Sjursen, H. and Pedersen, G. and Svindland, S. and Nostbakken, J. K. and Nilsen, M. and Mohn, K. and Jul-Larsen, A. and Smith, I. and Major, D. and Wood, J. and Cox, R. J.},\n\tmonth = dec,\n\tyear = {2010},\n\tkeywords = {Healthcare worker, Immunology, Pandemic influenza H1N1, Research \\& Experimental Medicine, Vaccine, a/duck/singapore/97 h5n3 vaccine, antibody, immunity, immunogenicity, mf59-adjuvanted influenza, safety, trial, viruses},\n\tpages = {266--273},\n}\n\n","author_short":["Madhun, A. S.","Akselsen, P. E.","Sjursen, H.","Pedersen, G.","Svindland, S.","Nostbakken, J. K.","Nilsen, M.","Mohn, K.","Jul-Larsen, A.","Smith, I.","Major, D.","Wood, J.","Cox, R. J."],"key":"madhun_adjuvanted_2010","id":"madhun_adjuvanted_2010","bibbaseid":"madhun-akselsen-sjursen-pedersen-svindland-nostbakken-nilsen-mohn-etal-anadjuvantedpandemicinfluenzah1n1vaccineprovidesearlyandlongtermprotectioninhealthcareworkers-2010","role":"author","urls":{"Paper":"https://bibbase.org/zotero/://WOS:000287057300015"},"keyword":["Healthcare worker","Immunology","Pandemic influenza H1N1","Research & Experimental Medicine","Vaccine","a/duck/singapore/97 h5n3 vaccine","antibody","immunity","immunogenicity","mf59-adjuvanted influenza","safety","trial","viruses"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/vincentwntu","creationDate":"2020-01-26T03:06:33.923Z","downloads":0,"keywords":["healthcare worker","immunology","pandemic influenza h1n1","research & experimental medicine","vaccine","a/duck/singapore/97 h5n3 vaccine","antibody","immunity","immunogenicity","mf59-adjuvanted influenza","safety","trial","viruses"],"search_terms":["adjuvanted","pandemic","influenza","h1n1","vaccine","provides","early","long","term","protection","health","care","workers","madhun","akselsen","sjursen","pedersen","svindland","nostbakken","nilsen","mohn","jul-larsen","smith","major","wood","cox"],"title":"An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers","year":2010,"dataSources":["icTw8KRRMMANXJHRd"]}