Infection-resistant MRI-visible scaffolds for tissue engineering applications. Mahmoudi, M, Zhao, M, Matsuura, Y, Laurent, S, Yang, P., Bernstein, D, Ruiz-Lozano, P, & Serpooshan, V Bioimpacts, 6(2):111–115, 2016.
Infection-resistant MRI-visible scaffolds for tissue engineering applications. [link]Paper  doi  abstract   bibtex   
Tissue engineering utilizes porous scaffolds as template to guide the new tissue growth. Clinical application of scaffolding biomaterials is hindered by implant-associated infection and impaired in vivo visibility of construct in biomedical imaging modalities. We recently demonstrated the use of a bioengineered type I collagen patch to repair damaged myocardium. By incorporating superparamagnetic iron oxide nanoparticles into this patch, here, we developed an MRI-visible scaffold. Moreover, the embedded nanoparticles impeded the growth of Salmonella bacteria in the patch. Conferring anti-infection and MRI-visible activities to the engineered scaffolds can improve their clinical outcomes and reduce the morbidity/mortality of biomaterial-based regenerative therapies.
@article{mahmoudi_infection-resistant_2016,
	title = {Infection-resistant {MRI}-visible scaffolds for tissue engineering applications.},
	volume = {6},
	issn = {2228-5652},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/27525229},
	doi = {10.15171/bi.2016.16},
	abstract = {Tissue engineering utilizes porous scaffolds as template to guide the new tissue growth. Clinical application of scaffolding biomaterials is hindered by implant-associated infection and impaired in vivo visibility of construct in biomedical imaging modalities. We recently demonstrated the use of a bioengineered type I collagen patch to repair damaged myocardium. By incorporating superparamagnetic iron oxide nanoparticles into this patch, here, we developed an MRI-visible scaffold. Moreover, the embedded nanoparticles impeded the growth of Salmonella bacteria in the patch. Conferring anti-infection and MRI-visible activities to the engineered scaffolds can improve their clinical outcomes and reduce the morbidity/mortality of biomaterial-based regenerative therapies.},
	language = {eng},
	number = {2},
	journal = {Bioimpacts},
	author = {Mahmoudi, M and Zhao, M and Matsuura, Y and Laurent, S and Yang, PC and Bernstein, D and Ruiz-Lozano, P and Serpooshan, V},
	year = {2016},
	keywords = {nanoparticles},
	pages = {111--115}
}
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