A semi-automatic technique to quantify complex tuberculous lung lesions on 18 F-fluorodeoxyglucose positron emission tomography/computerised tomography images. Malherbe, S. T, Dupont, P., Kant, I., Ahlers, P., Kriel, M., Loxton, A. G, Chen, R. Y, Via, L. E, Thienemann, F., Wilkinson, R. J, Barry, C. E, Griffith-Richards, S., Ellman, A., Ronacher, K., Winter, J., Walzl, G., & Warwick, J. M EJNMMI Research, 8:55, 2018. ![A semi-automatic technique to quantify complex tuberculous lung lesions on 18 F-fluorodeoxyglucose positron emission tomography/computerised tomography images [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Background: There is a growing interest in the use of 18 F-FDG PET-CT to monitor tuberculosis (TB) treatment response. However, TB causes complex and widespread pathology, which is challenging to segment and quantify in a reproducible manner. To address this, we developed a technique to standardise uptake (Z-score), segment and quantify tuberculous lung lesions on PET and CT concurrently, in order to track changes over time. We used open source tools and created a MATLAB script. The technique was optimised on a training set of five pulmonary tuberculosis (PTB) cases after standard TB therapy and 15 control patients with lesion-free lungs.
@article{Malherbe2018,
abstract = {Background: There is a growing interest in the use of 18 F-FDG PET-CT to monitor tuberculosis (TB) treatment response. However, TB causes complex and widespread pathology, which is challenging to segment and quantify in a reproducible manner. To address this, we developed a technique to standardise uptake (Z-score), segment and quantify tuberculous lung lesions on PET and CT concurrently, in order to track changes over time. We used open source tools and created a MATLAB script. The technique was optimised on a training set of five pulmonary tuberculosis (PTB) cases after standard TB therapy and 15 control patients with lesion-free lungs.},
author = {Malherbe, Stephanus T and Dupont, Patrick and Kant, Ilse and Ahlers, Petri and Kriel, Magdalena and Loxton, Andr{\'{e}} G and Chen, Ray Y and Via, Laura E and Thienemann, Friedrich and Wilkinson, Robert J and Barry, Clifton E and Griffith-Richards, Stephanie and Ellman, Annare and Ronacher, Katharina and Winter, Jill and Walzl, Gerhard and Warwick, James M},
doi = {10.1186/s13550-018-0411-7},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Malherbe et al. - 2018 - A semi-automatic technique to quantify complex tuberculous lung lesions on 18 F-fluorodeoxyglucose positron emi.pdf:pdf},
journal = {EJNMMI Research},
keywords = {OA,fund{\_}ack,original},
mendeley-tags = {OA,fund{\_}ack,original},
pages = {55},
pmid = {29943161},
title = {{A semi-automatic technique to quantify complex tuberculous lung lesions on 18 F-fluorodeoxyglucose positron emission tomography/computerised tomography images}},
url = {https://doi.org/10.1186/s13550-018-0411-7},
volume = {8},
year = {2018}
}
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