Efficacy of Intravenous Lidocaine in Preventing Laryngospasm in Children Undergoing Tonsillectomy. Malik A., Butt T.A., Akhtar N., & Ashraf Z. 2016.
Efficacy of Intravenous Lidocaine in Preventing Laryngospasm in Children Undergoing Tonsillectomy [pdf]Paper  abstract   bibtex   
Background: Laryngospasm is a well-known problem typically occurring immediately following tracheal extubation. Lidocaine is known to inhibit airway reflexes. Pediatric laryngospasm is an anesthetic emergency. It is a relatively common phenomenon that occurs with varying frequency dependent on multiple factors. Treating laryngospasm by using lidocaine is controversial. Aim: To compare the efficacy of intravenous lidocaine with placebo for prevention of laryngospasm in children undergoing tonsillectomy. Methods: This was a randomized controlled trail conducted in the department of Anesthesia, Mayo Hospital Lahore. Total 150 patients were included in the study and randomly divided into 2 groups. Each group contained 75 patients each. In Group-P patients were given placebo and in Group-L patients were given IV Lidocaine. Informed consent was taken from parents of each patient in both treatment groups. Relevant information was recorded on a well-defined Performa. Data entry and analysis was done by using SPSS 11.5. Results: Average age of all 150 patients was 8.33+/-2.33 years. Average age of patients in Group-P and in Group-L was 8.09+/-2.37 and 8.56+/-2.32 years respectively. In placebo group laryngospasm was present in 20% and in Lidocaine group 8% of the patients had laryngospasm. Efficacy of Lidocaine in controlling laryngospasm was 92% where as efficacy of placebo group was 80%. Lidocaine shows greater efficacy for controlling laryngospasm. Conclusion: On the basis of obtained results it is concluded that Lidocaine effectively controls laryngospasm in children undergoing Tonsillectomy.
@misc{malik_a._efficacy_2016,
	title = {Efficacy of {Intravenous} {Lidocaine} in {Preventing} {Laryngospasm} in {Children} {Undergoing} {Tonsillectomy}},
	url = {http://pjmhsonline.com/2016/oct_dec/pdf/1182.pdf},
	abstract = {Background: Laryngospasm is a well-known problem typically occurring immediately following tracheal extubation. Lidocaine is known to inhibit airway reflexes. Pediatric laryngospasm is an anesthetic emergency. It is a relatively common phenomenon that occurs with varying frequency dependent on multiple factors. Treating laryngospasm by using lidocaine is controversial. Aim: To compare the efficacy of intravenous lidocaine with placebo for prevention of laryngospasm in children undergoing tonsillectomy. Methods: This was a randomized controlled trail conducted in the department of Anesthesia, Mayo Hospital Lahore. Total 150 patients were included in the study and randomly divided into 2 groups. Each group contained 75 patients each. In Group-P patients were given placebo and in Group-L patients were given IV Lidocaine. Informed consent was taken from parents of each patient in both treatment groups. Relevant information was recorded on a well-defined Performa. Data entry and analysis was done by using SPSS 11.5. Results: Average age of all 150 patients was 8.33+/-2.33 years. Average age of patients in Group-P and in Group-L was 8.09+/-2.37 and 8.56+/-2.32 years respectively. In placebo group laryngospasm was present in 20\% and in Lidocaine group 8\% of the patients had laryngospasm. Efficacy of Lidocaine in controlling laryngospasm was 92\% where as efficacy of placebo group was 80\%. Lidocaine shows greater efficacy for controlling laryngospasm. Conclusion: On the basis of obtained results it is concluded that Lidocaine effectively controls laryngospasm in children undergoing Tonsillectomy.},
	journal = {Pakistan Journal of Medical and Health Sciences},
	author = {{Malik A.} and {Butt T.A.} and {Akhtar N.} and {Ashraf Z.}},
	year = {2016},
	keywords = {*larynx spasm, *larynx spasm/dt [Drug Therapy], *larynx spasm/pc [Prevention], *larynx spasm/th [Therapy], *lidocaine, *lidocaine/cm [Drug Comparison], *lidocaine/dt [Drug Therapy], *lidocaine/iv [Intravenous Drug Administration], *placebo, *tonsillectomy, Anesthesia, Child, aged, article, comparative effectiveness, conservative treatment, controlled clinical trial, controlled study, data analysis software, disease severity, drug efficacy, drug therapy, female, hospital, human, informed consent, jaw thrust, larynx spasm/dt [Drug Therapy], major clinical study, male, outcome assessment, oxygenation, placebo, positive end expiratory pressure, prevention, randomized controlled trial, tonsillitis/su [Surgery], very elderly}
}
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