@article{Markovits1983,
	title = {Dynamic structure of {DNA} complexes. {Fluorometric} measurement of hydrogen-deuterium exchange kinetics of {DNA}-bound ethidium dimer and acridine-ethidium dimer},
	volume = {22},
	issn = {0006-2960},
	url = {http://pubs.acs.org/doi/abs/10.1021/bi00282a030},
	doi = {10.1021/bi00282a030},
	abstract = {The hydrogen-deuterium (H-D) exchange kinetics of free and DNA-bound ethidium dimer and acridine-ethidium heterodimer were measured by stopped flow using fluorescence detection. This technique allowed a very accurate measurement of the exchange process. The H-D exchange kinetics were measured in various environments. In some cases, it was observed that the H-D exchange was much faster than the dissociation rate of dimer-DNA complexes. This showed that the exchange was taking place directly from the bound state. Furthermore, the action of a catalyst (imidazolium ion) on the rate of H-D exchange showed that a dynamic structural fluctuation of the ligand in its DNA complex was a necessary step on the exchange process.},
	number = {13},
	journal = {Biochemistry},
	author = {Markovits, J. and Ramstein, J. and Roques, B. P. and Pecq, J. B. Le},
	month = jun,
	year = {1983},
	pmid = {6882747},
	note = {tex.ids= markovitsDynamicStructureDNA1983},
	pages = {3231--3237},
}

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