A saltationist theory of cancer evolution. Markowetz, F. Nat. Genet., 48(10):1102--1103, Nature Research, 28~September, 2016. doi abstract bibtex A new study based on single-nucleus sequencing reports that triple-negative breast cancers acquire copy number aberrations in short punctuated bursts in the earliest stages of tumor evolution, rather than continuously and gradually, challenging prevailing models of tumor evolution.
@ARTICLE{Markowetz2016-vp,
title = "A saltationist theory of cancer evolution",
author = "Markowetz, Florian",
abstract = "A new study based on single-nucleus sequencing reports that
triple-negative breast cancers acquire copy number aberrations
in short punctuated bursts in the earliest stages of tumor
evolution, rather than continuously and gradually, challenging
prevailing models of tumor evolution.",
journal = "Nat. Genet.",
publisher = "Nature Research",
volume = 48,
number = 10,
pages = "1102--1103",
month = "28~" # sep,
year = 2016,
keywords = "chromothripsis;evolution;perspectives;preface;darwinian;brca;pcne;Classics",
language = "en",
issn = "1061-4036, 1546-1718",
doi = "10.1038/ng.3687"
}
Downloads: 0
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