Severe Acute Respiratory Syndrome (SARS). Marraro, G. A. Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy, 54(1):9–20, 2003. ![Severe Acute Respiratory Syndrome (SARS) [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper abstract bibtex An extremely severe and rapidly spreading pulmonary disease has made its appearance between the end of 2002 and the first half of 2003, involving mostly asiatic countries and particularly China, Hong Kong, Taiwan, Singapore and Canada. While in China the disease, due to a new corona-virus Sco-V, was initiated by primary infection, in the other countries it was due either to contagion or inadequate control of suspicious cases. The disease showed a a very severe course in adults, with a 5-10% mortality, while in children it was less frequent and severe. Health care personnel have been significantly exposed and infected, due to the ease of diffusion and lack of knowledge about individuals at risk. WHO efforts in the attempt to block as soon as possible the transmission of infection have succeeded in limiting diffusion and avoiding the risk of a pandemic. Exceptional and unprecedented has been the tight cooperation of researchers all over the world aiming at identifying the pathogenetic agent and describing its sequence and mutability, thus providing useful informations for prevention and treatment and opening the way to the preparation of a vaccine. To date, no specific and effective therapy is available, and no recommendation can be made as to how to approach each single patient. Different kinds of antibiotics have been used to counteract concomitant community-acquired infections or evident bacterial superinfections. Ribavirin and steroids have had only anecdotal reports. Respiratory intensive care by means of non invasive ventilation seemed to give better results. Those more severe cases that needed artificial ventilation had a greater mortality rate. Not knowing whether the disease is going to outbreak again in a next future and with what severity and diffusion capability, it is mandatory that preventive measures be taken in each and every hospital aginst all typical and atypical pulmonary infections, remembering always to keep a suspicious mind.
@article{marraro_severe_2003,
title = {Severe {Acute} {Respiratory} {Syndrome} ({SARS})},
volume = {54},
issn = {1124-8882},
url = {http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed8&NEWS=N&AN=37345583},
abstract = {An extremely severe and rapidly spreading pulmonary disease has made its appearance between the end of 2002 and the first half of 2003, involving mostly asiatic countries and particularly China, Hong Kong, Taiwan, Singapore and Canada. While in China the disease, due to a new corona-virus Sco-V, was initiated by primary infection, in the other countries it was due either to contagion or inadequate control of suspicious cases. The disease showed a a very severe course in adults, with a 5-10\% mortality, while in children it was less frequent and severe. Health care personnel have been significantly exposed and infected, due to the ease of diffusion and lack of knowledge about individuals at risk. WHO efforts in the attempt to block as soon as possible the transmission of infection have succeeded in limiting diffusion and avoiding the risk of a pandemic. Exceptional and unprecedented has been the tight cooperation of researchers all over the world aiming at identifying the pathogenetic agent and describing its sequence and mutability, thus providing useful informations for prevention and treatment and opening the way to the preparation of a vaccine. To date, no specific and effective therapy is available, and no recommendation can be made as to how to approach each single patient. Different kinds of antibiotics have been used to counteract concomitant community-acquired infections or evident bacterial superinfections. Ribavirin and steroids have had only anecdotal reports. Respiratory intensive care by means of non invasive ventilation seemed to give better results. Those more severe cases that needed artificial ventilation had a greater mortality rate. Not knowing whether the disease is going to outbreak again in a next future and with what severity and diffusion capability, it is mandatory that preventive measures be taken in each and every hospital aginst all typical and atypical pulmonary infections, remembering always to keep a suspicious mind.},
language = {Italian},
number = {1},
journal = {Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy},
author = {Marraro, G. A.},
year = {2003},
keywords = {*respiratory distress syndrome/ep [Epidemiology], *ribavirin, *severe acute respiratory syndrome/ep [Epidemiology], *steroid, Coronavirus, World Health Organization, clinical feature, disease course, disease transmission, health care personnel, human, infection control, intensive care, lung infection, primary infection, review, sequence analysis, superinfection},
pages = {9--20},
}
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Health care personnel have been significantly exposed and infected, due to the ease of diffusion and lack of knowledge about individuals at risk. WHO efforts in the attempt to block as soon as possible the transmission of infection have succeeded in limiting diffusion and avoiding the risk of a pandemic. Exceptional and unprecedented has been the tight cooperation of researchers all over the world aiming at identifying the pathogenetic agent and describing its sequence and mutability, thus providing useful informations for prevention and treatment and opening the way to the preparation of a vaccine. To date, no specific and effective therapy is available, and no recommendation can be made as to how to approach each single patient. Different kinds of antibiotics have been used to counteract concomitant community-acquired infections or evident bacterial superinfections. Ribavirin and steroids have had only anecdotal reports. Respiratory intensive care by means of non invasive ventilation seemed to give better results. Those more severe cases that needed artificial ventilation had a greater mortality rate. 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